Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Reza Ghassemifar"'
Publikováno v:
Leukemia Research. 51:56-61
B-cell chronic lymphocytic leukaemia (CLL) is characterized by an accumulation of CD5-positive monoclonal B-cells due in large part to a failure of apoptosis. The ability to study CLL B-cells in vitro has always been a challenge and hampered by the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160d5be5ede2e40b2d2a68b6bb252ae8
https://doi.org/10.1016/j.leukres.2016.10.011
https://doi.org/10.1016/j.leukres.2016.10.011
Publikováno v:
Biochemical Genetics. 54:714-721
Beta (β)-thalassaemic erythroblasts grown in vitro have reduced nuclear factor kappa B (NF-κB) pathway gene expression. By inhibiting this pathway in erythroblasts from normal individuals, important downstream genes affected by this inhibition can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921a6380067cd27634624f6db57dc6e0
https://doi.org/10.1007/s10528-016-9750-0
https://doi.org/10.1007/s10528-016-9750-0
Publikováno v:
British Journal of Haematology. 175:539-542
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2792a84d77adcc877a148b8101737554
https://doi.org/10.1111/bjh.13875
https://doi.org/10.1111/bjh.13875
Publikováno v:
Hemoglobin. 39:88-94
In recent years, the identification of α-thalassemias caused by nondeletional mutations has increased significantly due to the advancement of sensitive molecular genetics tools. We report clinical and experimental data for a novel frameshift mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb37208c300951acb5940ecc661327ce
https://doi.org/10.3109/03630269.2015.1016958
https://doi.org/10.3109/03630269.2015.1016958
Publikováno v:
Hemoglobin
Hemoglobin, Informa Healthcare, 2013, 38 (1), pp.13-18. ⟨10.3109/03630269.2013.858639⟩
Hemoglobin, Informa Healthcare, 2013, 38 (1), pp.13-18. ⟨10.3109/03630269.2013.858639⟩
In this study, we describe the clinical features and provide experimental analyses of a novel point mutation affecting the penultimate nucleotide of the first exon of the HBA2 (HBA2: c.94AG) gene identified in a 26-year-old female who also carries a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701920c4ef94ed0978717939bdbde20f
https://doi.org/10.3109/03630269.2013.858639
https://doi.org/10.3109/03630269.2013.858639
Autor:
Gavin Cull, Luke Forster, David Joske, Tony Calogero, Brad Augustson, Reza Ghassemifar, Jill Finlayson
Publikováno v:
Pathology. 44:632-637
Summary Aim To examine the relative gene expression levels of the anti-apoptotic Bcl-2α and β isoforms and the pro-apoptotic Baxα and β isoforms in patients with chronic lymphocytic leukaemia (CLL) and healthy controls (HC). Methods Peripheral bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495bbb68561163980ae81243d6fd0309
https://doi.org/10.1097/pat.0b013e32835a0142
https://doi.org/10.1097/pat.0b013e32835a0142
Autor:
Reza Ghassemifar, Paula Holmes, Laura Greenwood, Christopher Newbound, Nicole Pell, Dianne Grey, Jill Finlayson, John Beilby, Michelle Jennens
Publikováno v:
Hemoglobin. 36:511-515
We describe two frameshift mutations associated with an α-thalassemia (α-thal) phenotype, identified in three unrelated individuals investigated for persistent microcytosis. The first mutation, HBA2:c.131delT, is located in codon 43, and the second
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764fef6fdb19c9c8900e0643cfa866b2
https://doi.org/10.3109/03630269.2012.717053
https://doi.org/10.3109/03630269.2012.717053
Autor:
Russell L. McInnes, Marcus D. Atlas, Reza Ghassemifar, Peter L. Santa Maria, Sharon L. Redmond
Publikováno v:
The Laryngoscope. 121:2199-2213
Objectives/hypothesis The aim of this study is to elucidate transcriptional changes that occur in response to tympanic membrane (TM) perforation in rats and to infer key genes and molecular events in the healing process. Study design A prospective co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1442090c159be29f2b57131468ab9bd3
https://doi.org/10.1002/lary.22150
https://doi.org/10.1002/lary.22150
Autor:
Laura Greenwood, Claire Macaulay, Paula Holmes, Reza Ghassemifar, Jill Finlayson, Christopher Newbound, Michelle Jennens, Dianne Grey, John Beilby, Nicole Pell
Publikováno v:
Hemoglobin. 35:142-146
We describe a novel frameshift mutation associated with an α-thalassemia (α-thal) phenotype in a patient of Sudanese origin investigated for persistent microcytosis. In addition to the α(3.7) deletion, a novel mutation on the α2 gene was detected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ec8c602ca08f949552090f803e3027
https://doi.org/10.3109/03630269.2011.557462
https://doi.org/10.3109/03630269.2011.557462
Publikováno v:
Journal of Molecular Histology. 42:47-58
The aim of this study was to provide a transcriptome profile of Keratinocyte Growth Factor (KGF)-1, Fibroblast Growth Factor (FGF) 2 and FGF10 (KGF2) in the healing rat tympanic membrane (TM) over 7 days and an immunohistochemical account over 14 day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d199d6287868b8e4991a8bd4fca41f7
https://doi.org/10.1007/s10735-010-9306-2
https://doi.org/10.1007/s10735-010-9306-2