Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Reza Afarin"'
Autor:
Reza Afarin, Negar Dinarvand, Hossein Azizi Dariuni, Ghazal Orak, Bahar Jaberian Asl, Reza Azizi, Azam Khedri
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 8, Pp 1015-1022 (2024)
Objective(s): Non-alcoholic fatty liver disease (NAFLD) is a chronic steatohepatitis disorder. If left untreated, it can progress to hepatocellular carcinoma. Several studies have shown that saroglitazar, a PPARα/γ dual agonist, and curcumin (the p
Externí odkaz:
https://doaj.org/article/55c5666d5f174315a54889ca5cc6a2ce
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 9, Pp 1096-1104 (2024)
Objective(s): Liver diseases, including non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), pose significant global public health challenges. This study investigates the therapeutic effects of quercetin (QC), Capparis
Externí odkaz:
https://doaj.org/article/f338c6c7807b4d61abeb5b72432b4763
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31925- (2024)
Background: Breast cancer is a major global cancer, for which radiation and chemotherapy are the main treatments. Natural remedies are being studied to reduce the side effects. Etoposide (ETO), a chemo-drug, and quercetin (QC), a phytochemical, are c
Externí odkaz:
https://doaj.org/article/54f58afb791e4f709bfcd957dd1cb37f
Autor:
Reza Afarin, Negar Dinarvand, Bahar Jaberian Asl, Ghazal Orak, Elham Shakerian, Fatemeh Bineshfar, Akram Ahangarpour
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 2, Pp 241-246 (2024)
Objective(s): Non-alcoholic fatty liver disease (NAFLD) is the most common liver-related metabolic disorder in the world, with a global prevalence of 25%. Compounds with anti-inflammatory, lipid-lowering, and insulin-sensitizing properties can be use
Externí odkaz:
https://doaj.org/article/b59eaca85475477a8a3e1c4d34d668b6
Autor:
Mojtaba Rashidi, Emad Matour, Sajad Monjezi, Shahla Asadi Zadeh, Elham Shakerian, Sahar Sabahy, Reza Afarin
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 26, Iss 6, Pp 695-700 (2023)
Objective(s): Free cholesterol in the diet can cause liver fibrosis by accumulating in Hepatic stellate cells (HSCs). The rate of mortality of this disease is high worldwide and there is no definite remedy for it, but might be treated by anti-fibroti
Externí odkaz:
https://doaj.org/article/7fdcf14dab5342ebadf527f13049ea99
Autor:
Reza Afarin, Tahereh Behdarvand, Elham Shakerian, Samaneh Salehipour Bavarsad, Mojtaba Rashidi
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 25, Iss 12, Pp 1498-1503 (2022)
Objective(s): Activated cells which are called star-shaped cells, are some of the key factors in the development of liver fibrosis. Activation of NADPH oxidase (NOX) is associated with increased HSCs activity and progression of hepatic fibrosis. In t
Externí odkaz:
https://doaj.org/article/14c05429e6c94d09b13ca543322d7836
Autor:
Mojtaba Rashidi, Reza Afarin, Elham Shakerian, Shahla Asadizadeh, Samaneh Salehipour Bavarsad
Publikováno v:
مجله دانشکده پزشکی اصفهان, Vol 40, Iss 664, Pp 172-178 (2022)
Background: Liver fibrosis is a chronic disease caused by viral infections (such as hepatitis B and C viruses), alcohol abuse, and metabolic and genetic disorders that leads to excessive accumulation of extracellular matrix proteins, including collag
Externí odkaz:
https://doaj.org/article/11859fbd15dd41548b7c81dadf576fc9
Autor:
Rasoul Akbari, Tahereh Behdarvand, Reza Afarin, Hamid Yaghooti, Mohammad Taha Jalali, Narges Mohammadtaghvaei
Publikováno v:
BMC Pharmacology and Toxicology, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Background Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) have become significant global health concerns. In the present study, we aimed to investigate the effects of saroglitazar, a dual PPARα/γ agonist
Externí odkaz:
https://doaj.org/article/d4b2747331e24eab9f7d285709294f24
Autor:
Fereshteh Aslani, Reza Afarin, Nafiseh Dehghani Madiseh, Hasti Beheshti Nasab, Sajad Monjezi, Somayeh Igder, Mojtaba Rashidi
Publikováno v:
Hepatitis Monthly. 23
Background: Hepatocellular carcinoma (HCC) is the most common type of liver cancer worldwide. The current remedies for cancer, including chemotherapy and radiation therapy, might damage patients’ organs, sometimes causing death. Etoposide (ETO), as
Publikováno v:
Molecular Biology Reports. 49:2839-2845
Hepatic fibrosis is one of the main reasons for mortality in the world. Hepatic stellate cells (HSCs) activate during chronic liver injury, express more Transforming growth factor beta (TGF-β), Collagen1α (COLA1) and actin-alpha smooth muscle (αSM