Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Reza, Saberianfar"'
Autor:
Evan Sawula, Shane Miersch, Eric D. Jong, Chengjin Li, Fang-Yu Chou, Jean Kit Tang, Reza Saberianfar, Jeffrey Harding, Sachdev S. Sidhu, Andras Nagy
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Immunologically impaired individuals respond poorly to vaccines, highlighting the need for additional strategies to protect these vulnerable populations from COVID-19. While monoclonal antibodies (mAbs) have emerged as promising t
Externí odkaz:
https://doaj.org/article/e59caee950d2466e9ef888001b73da51
Autor:
Kushal Suryamohan, Devan Diwanji, Eric W. Stawiski, Ravi Gupta, Shane Miersch, Jiang Liu, Chao Chen, Ying-Ping Jiang, Frederic A. Fellouse, J. Fah Sathirapongsasuti, Patrick K. Albers, Tanneeru Deepak, Reza Saberianfar, Aakrosh Ratan, Gavin Washburn, Monika Mis, Devi Santhosh, Sneha Somasekar, G. H. Hiranjith, Derek Vargas, Sangeetha Mohan, Sameer Phalke, Boney Kuriakose, Aju Antony, Mart Ustav Jr, Stephan C. Schuster, Sachdev Sidhu, Jagath R. Junutula, Natalia Jura, Somasekar Seshagiri
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Suryamohan, Diwanji, Stawiski et al. identify natural ACE2 variants that are predicted to alter virus–host interactions. They find that soluble ACE2 K26R and T92I variants are more effective in blocking the entry of SARS-CoV-2 S-protein pseudotyped
Externí odkaz:
https://doaj.org/article/32225ac91a454b1683c6a373e209aa04
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
We previously isolated a single domain antibody (VHH) that binds Enterohemorrhagic Escherichia coli (EHEC) with the end-goal being the enteromucosal passive immunization of cattle herds. To improve the yield of a chimeric fusion of the VHH with an Ig
Externí odkaz:
https://doaj.org/article/537493922172428db6e123128a972950
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Enterohemorrhagic Escherichia coli (EHEC) has consistently been one of the foremost foodborne pathogen threats worldwide based on the past 30 years of surveillance. EHEC primarily colonizes the bovine gastrointestinal (GI) tract from which it can be
Externí odkaz:
https://doaj.org/article/596bc997754a430ab48a900c2f6e852e
Autor:
Jonathan M. Labriola, Shane Miersch, Gang Chen, Chao Chen, Alevtina Pavlenco, Reza Saberianfar, Francesca Caccuri, Alberto Zani, Nitin Sharma, Annie Feng, Daisy W. Leung, Arnaldo Caruso, Giuseppe Novelli, Gaya K. Amarasinghe, Sachdev S. Sidhu
The spread of COVID-19 has been exacerbated by the emergence of variants of concern (VoC). Many VoC contain mutations in the spike protein (S-protein) and are implicated in infection and response to therapeutics. Bivalent neutralizing antibodies (nAb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dff5fe691f156f2f73a8065601ecdb6
http://hdl.handle.net/11379/562608
http://hdl.handle.net/11379/562608
Autor:
Nitin Sharma, Chao Chen, Alberto Zani, Arnaldo Caruso, Shane Miersch, Gaya K. Amarasinghe, Sachdev S. Sidhu, Francesca Caccuri, Reza Saberianfar, Giuseppe Novelli
Neutralizing antibodies (nAbs) that target the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein (S-protein) are promising therapeutics for COVID-19. However, natural bivalent nAbs suffer from limited potency and are vulnerable to SARS-Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446acbc62505e11d64edb5ec03a2da5c
https://doi.org/10.1101/2021.11.02.466984
https://doi.org/10.1101/2021.11.02.466984
Autor:
Sameer Phalke, Patrick K. Albers, Sangeetha Mohan, Aju Antony, Chao Chen, Aakrosh Ratan, Jiang Liu, Kushal Suryamohan, Natalia Jura, Sachdev S. Sidhu, G. H. Hiranjith, Ravi Gupta, J. Fah Sathirapongsasuti, Reza Saberianfar, Devan Diwanji, Somasekar Seshagiri, Shane Miersch, Frederic A. Fellouse, Sneha Somasekar, Devi Santhosh, Mart Ustav, Boney Kuriakose, Derek Vargas, Stephan C. Schuster, Tanneeru Deepak, Jagath Reddy Junutula, Gavin Washburn, Eric Stawiski, Monika Mis, Ying-Ping Jiang
Publikováno v:
Communications biology, vol 4, iss 1
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
COVID-19 is a respiratory illness caused by a novel coronavirus called SARS-CoV-2. The viral spike (S) protein engages the human angiotensin-converting enzyme 2 (ACE2) receptor to invade host cells with ~10–15-fold higher affinity compared to SARS-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::072138f1476c794422e51b207dc8ef9a
https://escholarship.org/uc/item/36g6j945
https://escholarship.org/uc/item/36g6j945
Autor:
Stefan Rentas, Reza Saberianfar, Charnpal Grewal, Rachelle Kanippayoor, Mithilesh Mishra, Dannel McCollum, Jim Karagiannis
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31224 (2012)
In response to perturbation of the cell division machinery fission yeast cells activate regulatory networks that ensure the faithful completion of cytokinesis. For instance, when cells are treated with drugs that impede constriction of the actomyosin
Externí odkaz:
https://doaj.org/article/4e39b9fa4f034d7b849158370829a0d7
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24694 (2011)
In Schizosaccharomyces pombe the nuclear-localized Lsk1p-Lsc1p cyclin dependent kinase complex promotes Ser-2 phosphorylation of the heptad repeats found within the RNA pol II carboxy terminal domain (CTD). Here, we first provide evidence supporting
Externí odkaz:
https://doaj.org/article/00105c2b64134b34a09dba533033046b
Autor:
Rima Menassa, Reza Saberianfar
Publikováno v:
Plant Biotechnology Journal
Protein bodies (PBs) are highly specialized protein storage organelles in cereal seeds. PB formation in seeds initiates in the endoplasmic reticulum (ER), and depending on the plant species, PBs remain in the ER or find their way out of the ER, bypas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f18623c2f63fc5445c95ba20350105
https://doi.org/10.1111/pbi.12730
https://doi.org/10.1111/pbi.12730