Zobrazeno 1 - 10
of 330
pro vyhledávání: '"Reynolds, N.J."'
Autor:
Jans, R., Mottram, L., Johnson, D.L., Brown, A.M., Sikkink, Stephen, Ross, K., Reynolds, N.J.
Lysophosphatidic acid (LPA) enhances cell migration and promotes wound healing in vivo, but the intracellular signaling pathways regulating these processes remain incompletely understood. Here we investigated the involvement of agonist-induced Ca2+ e
Externí odkaz:
http://hdl.handle.net/10454/7256
Autor:
Dambha-Miller, Hajira, Farmer, Andrew, Nirantharakumar, K., Jackson, T., Yau, C., Walker, L., Buchan, I., Finer, S., Barnes, M.R., Reynolds, N.J., Jun, GT, Gangadharan, S, Fraser, Simon, Guthrie, Bruce
Recent advances in causal machine learning and wider artificial intelligence (AI) methods could provide new insights into the natural histories and potential prevention of clusters of multiple long-term conditions or multimorbidity (MLTC-M). When com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______348::7fb7ee9a124bbc231ed95f84426641fa
https://eprints.soton.ac.uk/477692/
https://eprints.soton.ac.uk/477692/
Akademický článek
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Autor:
Cro, S., Cornelius, V.R., Pink, A.E., Wilson, R., Pushpa‐Rajah, A., Patel, P., Abdul‐Wahab, A., August, S., Azad, J., Becher, G., Chapman, A., Dunnil, G., Ferguson, A.D., Fogo, A., Ghaffar, S.A., Ingram, J.R., Kavakleiva, S., Ladoyanni, E., Leman, J.A., Macbeth, A.E., Makrygeoegou, A., Parslew, R., Ryan, A.J., Sharma, A., Shipman, A.R., Sinclair, C., Wachsmuth, R., Woolf, R.T., Wright, A., McAteer, H., Barker, J.N.W.N., Burden, A.D., Griffiths, C.E.M., Reynolds, N.J., Warren, R.B., Lachmann, H.J., Capon, F., Smith, C.H., APRICOT Study Group
Background:\ud Palmoplantar pustulosis (PPP) is a rare, debilitating, chronic inflammatory skin disease that affects the hands and feet. Clinical, immunological and genetic findings suggest a pathogenic role for interleukin (IL)-1.\ud \ud Objectives:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::d5e5c0cbe1ee379a68c282e9c437d5f3
https://eprints.gla.ac.uk/250468/1/250468.pdf
https://eprints.gla.ac.uk/250468/1/250468.pdf
Akademický článek
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Autor:
Mahil, S.K., Wilson, N., Dand, N., Reynolds, N.J., Griffiths, C.E.M., Emsley, R., Marsden, A., Evans, I., Warren, R.B., Stocken, D., Barker, J.N., Burden, A.D., Smith, C.H.
Background\ud The ‘treat to target’ paradigm improves outcomes and reduces costs in chronic disease management but is not yet established in psoriasis.\ud \ud Objectives\ud To identify treatment targets in psoriasis using two common measures of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::dd2f34b61ad6a393f820e7a7760fc917
https://eprints.gla.ac.uk/190495/1/190495.pdf
https://eprints.gla.ac.uk/190495/1/190495.pdf
Autor:
Pan, S., Tsakok, T., Dand, N., Lonsdale, D.O., Loeff, F.C., Bloem, K., de Vries, A., Baudry, D., Duckworth, M., Mahil, S., Pushpa-Rajah, A., Russell, A., Alsharqi, A., Becher, G., Murphy, R., Wahie, S., Wright, A., Griffiths, C.E.M., Reynolds, N.J., Barker, J., Warren, R.B., David Burden, A., Rispens, T., Standing, J.F., Smith, C.H., Benham, M., Evans, I., Hussain, S., Kirby, B., Lawson, L., Mason, K., McElhone, K., Ormerod, A., Owen, C., Barnes, M.R., Di Meglio, P., Emsley, R., Evans, A., Payne, K.
Publikováno v:
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 13(2), 400-409. Wiley-Blackwell
Clinical and Translational Science, Vol 13, Iss 2, Pp 400-409 (2020)
Clinical and Translational Science
Pan, S, Tsakok, T, Dand, N, Lonsdale, D O, Loeff, F C, Bloem, K, de Vries, A, Baudry, D, Duckworth, M, Mahil, S, Pushpa-Rajah, A, Russell, A, Alsharqi, A, Becher, G, Murphy, R, Wahie, S, Wright, A, Griffiths, C E M, Reynolds, N J, Barker, J, Warren, R B, David Burden, A, Rispens, T & Standing, J F & Smith, C H 2020, ' Using Real-World Data to Guide Ustekinumab Dosing Strategies for Psoriasis : A Prospective Pharmacokinetic-Pharmacodynamic Study ', Clinical and Translational Science, vol. 13, no. 2, pp. 400-409 . https://doi.org/10.1111/cts.12725, https://doi.org/10.1111/cts.12725
Pan, S, Tsakok, T, Dand, N, Lonsdale, D O, Loeff, F C, Bloem, K, de Vries, A, Baudry, D, Duckworth, M, Mahil, S, Pushpa-Rajah, A, Russell, A, Alsharqi, A, Becher, G, Murphy, R, Wahie, S, Wright, A, Griffiths, C E M, Reynolds, N J, Barker, J, Warren, R B, David Burden, A, Rispens, T, Standing, J F, Smith, C H, Benham, M, Evans, I, Hussain, S, Kirby, B, Lawson, L, Mason, K, McElhone, K, Ormerod, A, Owen, C, Barnes, M R, Di Meglio, P, Emsley, R, Evans, A & Payne, K 2020, ' Using Real-World Data to Guide Ustekinumab Dosing Strategies for Psoriasis: A Prospective Pharmacokinetic-Pharmacodynamic Study ', Clinical and Translational Science, vol. 13, no. 2, pp. 400-409 . https://doi.org/10.1111/cts.12725
Clinical and Translational Science, Vol 13, Iss 2, Pp 400-409 (2020)
Clinical and Translational Science
Pan, S, Tsakok, T, Dand, N, Lonsdale, D O, Loeff, F C, Bloem, K, de Vries, A, Baudry, D, Duckworth, M, Mahil, S, Pushpa-Rajah, A, Russell, A, Alsharqi, A, Becher, G, Murphy, R, Wahie, S, Wright, A, Griffiths, C E M, Reynolds, N J, Barker, J, Warren, R B, David Burden, A, Rispens, T & Standing, J F & Smith, C H 2020, ' Using Real-World Data to Guide Ustekinumab Dosing Strategies for Psoriasis : A Prospective Pharmacokinetic-Pharmacodynamic Study ', Clinical and Translational Science, vol. 13, no. 2, pp. 400-409 . https://doi.org/10.1111/cts.12725, https://doi.org/10.1111/cts.12725
Pan, S, Tsakok, T, Dand, N, Lonsdale, D O, Loeff, F C, Bloem, K, de Vries, A, Baudry, D, Duckworth, M, Mahil, S, Pushpa-Rajah, A, Russell, A, Alsharqi, A, Becher, G, Murphy, R, Wahie, S, Wright, A, Griffiths, C E M, Reynolds, N J, Barker, J, Warren, R B, David Burden, A, Rispens, T, Standing, J F, Smith, C H, Benham, M, Evans, I, Hussain, S, Kirby, B, Lawson, L, Mason, K, McElhone, K, Ormerod, A, Owen, C, Barnes, M R, Di Meglio, P, Emsley, R, Evans, A & Payne, K 2020, ' Using Real-World Data to Guide Ustekinumab Dosing Strategies for Psoriasis: A Prospective Pharmacokinetic-Pharmacodynamic Study ', Clinical and Translational Science, vol. 13, no. 2, pp. 400-409 . https://doi.org/10.1111/cts.12725
Variation in response to biologic therapy for inflammatory diseases, such as psoriasis, is partly driven by variation in drug exposure. Real-world psoriasis data were used to develop a pharmacokinetic/pharmacodynamic (PK/PD) model for the first-line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcea23ca63518fef3372a4c62f0df85
https://pure.amc.nl/en/publications/using-realworld-data-to-guide-ustekinumab-dosing-strategies-for-psoriasis(356fdda6-87b8-4fbc-8cc1-218c18c81fd8).html
https://pure.amc.nl/en/publications/using-realworld-data-to-guide-ustekinumab-dosing-strategies-for-psoriasis(356fdda6-87b8-4fbc-8cc1-218c18c81fd8).html