Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Reynolds, Cody"'
Autor:
Pham, Thuong Le Hoai, Saurav, Jillur Rahman, Omere, Aisosa A., Heyl, Calvin J., Nasr, Mohammad Sadegh, Reynolds, Cody Tyler, Veerla, Jai Prakash Yadav, Shang, Helen H, Jaworski, Justyn, Ravenscraft, Alison, Buonomo, Joseph Anthony, Luber, Jacob M.
We introduce a protein language model for determining the complete sequence of a peptide based on measurement of a limited set of amino acids. To date, protein sequencing relies on mass spectrometry, with some novel edman degregation based platforms
Externí odkaz:
http://arxiv.org/abs/2408.00892
Autor:
Veerla, Jai Prakash, Guttikonda, Partha Sai, Hajighasemi, Amir, Saurav, Jillur Rahman, Darji, Aarti, Reynolds, Cody T., Mohamed, Mohamed, Nasr, Mohammad S., Shang, Helen H., Luber, Jacob M.
In contemporary pathology, multiplexed immunofluorescence (mIF) and multiplex immunohistochemistry (mIHC) present both significant opportunities and challenges. These methodologies shed light on intricate tumor microenvironment interactions, emphasiz
Externí odkaz:
http://arxiv.org/abs/2401.02882
Autor:
Aziz, Abdul, Pham, Nhat, Vora, Neel, Reynolds, Cody, Lehnen, Jaime, Venkatesh, Pooja, Yao, Zhuoran, Harvey, Jay, Vu, Tam, Ding, Kan, Nguyen, Phuc
Epilepsy is one of the most common neurological diseases globally (around 50 million people worldwide). Fortunately, up to 70% of people with epilepsy could live seizure-free if properly diagnosed and treated, and a reliable technique to monitor the
Externí odkaz:
http://arxiv.org/abs/2401.05425
Autor:
Vora, Neel R, Hajighasemi, Amir, Reynolds, Cody T., Radmehr, Amirmohammad, Mohamed, Mohamed, Saurav, Jillur Rahman, Aziz, Abdul, Veerla, Jai Prakash, Nasr, Mohammad S, Lotspeich, Hayden, Guttikonda, Partha Sai, Pham, Thuong, Darji, Aarti, Malidarreh, Parisa Boodaghi, Shang, Helen H, Harvey, Jay, Ding, Kan, Nguyen, Phuc, Luber, Jacob M
Head-based signals such as EEG, EMG, EOG, and ECG collected by wearable systems will play a pivotal role in clinical diagnosis, monitoring, and treatment of important brain disorder diseases. However, the real-time transmission of the significant cor
Externí odkaz:
http://arxiv.org/abs/2312.12587
Autor:
Donna Reynolds Cody, Zhou Hairong, Gordon W. Rewcastle, and Alan J. Kraker, H. D. Hollis Showalter, Amy McMichael, William A. Denny, Alexander James Bridges, David W. Fry
Publikováno v:
Journal of Medicinal Chemistry. 39:267-276
4-(3-Bromoanilino)-6,7-dimethoxyquinazoline (32, PD 153035) is a very potent inhibitor (IC50 0.025 nM) of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR), binding competitively at the ATP site. Structure-activity relations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809e33c3ab5369c307d3a8956f5474bd
https://doi.org/10.1021/jm9503613
https://doi.org/10.1021/jm9503613
Autor:
Alexander James Bridges, Zhou Hairong, David W. Fry, Andrew M. Thompson, Donna Reynolds Cody, Gordon W. Rewcastle, Brian D. Palmer, and Amy McMichael, William A. Denny
Publikováno v:
Journal of Medicinal Chemistry. 39:1823-1835
Following the discovery of the very high inhibitory ability of the 4-[(3-bromophenyl)amino]-quinazolines against the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) (e.g., 3, IC50 0.029 nM), four series of related pyrido[d]pyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ad0686b4a7da819ce3eeecf459ae34
https://doi.org/10.1021/jm9508651
https://doi.org/10.1021/jm9508651
Autor:
Donna Reynolds Cody, Mel C. Schroeder, Sheila Dewitt, Charles J. Stankovic, John S. Kiely, Michael R. Pavia
Publikováno v:
Proceedings of the National Academy of Sciences. 90:6909-6913
Solid-phase chemistry, organic synthesis, and an apparatus for multiple, simultaneous synthesis have been combined to generate libraries of organic compounds ("diversomers"). Arrays of compounds were synthesized over two to three steps incorporating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d395984d0dc012de6a87ebb7ee05895
https://doi.org/10.1073/pnas.90.15.6909
https://doi.org/10.1073/pnas.90.15.6909
Autor:
David W. Fry, Alexander James Bridges, William A. Denny, Gordon W. Rewcastle, Zhou Hairong, Amy McMichael, Donna Reynolds Cody
Publikováno v:
Journal of medicinal chemistry. 38(18)
A series of 4-substituted quinazolines and related compounds have been prepared and evaluated for their ability to inhibit the tyrosine kinase activity of the epidermal growth factor receptor on a phospholipase C-gamma 1-derived substrate. The result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12cf8c44095d022a3d09b893716bfc43
https://pubmed.ncbi.nlm.nih.gov/7658435
https://pubmed.ncbi.nlm.nih.gov/7658435
Publikováno v:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference [Annu Int Conf IEEE Eng Med Biol Soc] 2016 Aug; Vol. 2016, pp. 1991-1994.