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Epigenetic reprogramming of the male genome during gametogenesis and in the zygote

Autor: Rousseaux, S, Reynoird, N, Escoffier, E, Thevenon, J, Caron, C, Khochbin, S

Publikováno v: In Reproductive BioMedicine Online 2008 16(4):492-503

Nut Directs p300-Dependent, Genome-Wide H4 Hyperacetylation in Male Germ Cells

Autor: Shiota, H, Barral, S, Buchou, T, Tan, M, Couté, Y, Charbonnier, G, Reynoird, N, Boussouar, F, Gérard, M, Zhu, M, Bargier, L, Puthier, D, Chuffart, F, Bourova-Flin, E, Picaud, S, Filippakopoulos, P, Goudarzi, A, Ibrahim, Z, Panne, D, Rousseaux, S, Zhao, Y, Khochbin, S

Publikováno v: Cell Reports
Cell Reports, 2018, 24 (13), pp.3477-3487.e6. ⟨10.1016/j.celrep.2018.08.069⟩
Cell Reports, Elsevier Inc, 2018, 24 (13), pp.3477-3487.e6. ⟨10.1016/j.celrep.2018.08.069⟩
Cell Reports, Vol 24, Iss 13, Pp 3477-3487.e6 (2018)

International audience; Graphical Abstract Highlights d Nut is a post-meiotically expressed gene that is critical for male fertility d Nut recruits p300 and/or CBP to enhance histone H4K5 and H4K8 acetylation d Nut-mediated histone hyperacetylation i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5f196b55dad1702a08dbe9da688fa773
https://amu.hal.science/hal-01887337

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SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer

Autor: Butte, Atul, Mazur, PK, Reynoird, N, Khatri, P, Jansen, PWTC, Wilkinson, AW, Liu, S, Barbash, O, Van, GS, Huddleston, M, Dhanak, D

Publikováno v: Butte, Atul; Mazur, PK; Reynoird, N; Khatri, P; Jansen, PWTC; Wilkinson, AW; et al.(2014). SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2h57s8n8

Deregulation of lysine methylation signalling has emerged as a common aetiological factor in cancer pathogenesis, with inhibitors of several histone lysine methyltransferases (KMTs) being developed as chemotherapeutics. The largely cytoplasmic KMT SM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::5dc01a6aac34bc1cbeda010e5492e228
http://www.escholarship.org/uc/item/2h57s8n8