Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Reyno Delrosario"'
Autor:
Wei-Ching Chen, Minh D. To, Peter M. K. Westcott, Reyno Delrosario, Il-Jin Kim, Mark Philips, Quan Tran, Saumya R. Bollam, Hani Goodarzi, Nora Bayani, Olga Mirzoeva, Allan Balmain
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Kras is frequently mutated in lung cancer and two isoforms are generated via alternative splicing. Here, the authors show that the two isoforms have divergent roles in cancer stem cells and the main tumour cell population, which are regulated by hypo
Externí odkaz:
https://doaj.org/article/a22b5d5de40945018011a5128be0357a
Autor:
David A. Quigley, Eve Kandyba, Phillips Huang, Kyle D. Halliwill, Jonas Sjölund, Facundo Pelorosso, Christine E. Wong, Gillian L. Hirst, Di Wu, Reyno Delrosario, Atul Kumar, Allan Balmain
Publikováno v:
Cell Reports, Vol 16, Iss 4, Pp 1153-1165 (2016)
Inherited germline polymorphisms can cause gene expression levels in normal tissues to differ substantially between individuals. We present an analysis of the genetic architecture of normal adult skin from 470 genetically unique mice, demonstrating t
Externí odkaz:
https://doaj.org/article/4e4c950e68df4c5ebfbf014d72bdb593
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31301 (2012)
Genome-wide association studies (GWAS) have been successful in finding associations between specific genetic variants and cancer susceptibility in human populations. These studies have identified a range of highly statistically significant associatio
Externí odkaz:
https://doaj.org/article/b78b1717d9b844168cbe62d0cb3dc140
Autor:
Mark A. Taylor, Eve Kandyba, Kyle Halliwill, Reyno Delrosario, Matvei Koroshkin, Hani Goodarzi, David Quigley, Yun Rose Li, Di Wu, Saumya Bollam, Olga Mirzoeva, Rosemary J. Akhurst, Allan Balmain
Adult mammalian stem cells play critical roles in normal tissue homeostasis, as well as in tumor development, by contributing to cell heterogeneity, plasticity, and development of drug resistance. The relationship between different types of normal an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce948eb8a49d3314c422f3a2d5bd0da6
https://doi.org/10.1101/2023.05.08.539863
https://doi.org/10.1101/2023.05.08.539863
Autor:
Jian-Hua Mao, Allan Balmain, Guangwei Wei, Jesus Perez-Losada, Kuang-Yu Jen, Reyno DelRosario, Hio Chung Kang, Yurong Huang, Yueyong Liu, William A. Stock, Jing Lu, Di Wu, Il-Jin Kim, Yong-Won Kwon
PDF file - 222K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409d249f5270f369a43e725ff50207e6
https://doi.org/10.1158/1541-7786.22516908.v1
https://doi.org/10.1158/1541-7786.22516908.v1
Autor:
Jian-Hua Mao, Allan Balmain, Guangwei Wei, Jesus Perez-Losada, Kuang-Yu Jen, Reyno DelRosario, Hio Chung Kang, Yurong Huang, Yueyong Liu, William A. Stock, Jing Lu, Di Wu, Il-Jin Kim, Yong-Won Kwon
The Aurora-A kinase gene is frequently amplified and/or overexpressed in a variety of human cancers, leading to major efforts to develop therapeutic agents targeting this pathway. Here, we show that Aurora-A is targeted for ubiquitination and subsequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4683175472a6d135526e2086cb935038
https://doi.org/10.1158/1541-7786.c.6541539
https://doi.org/10.1158/1541-7786.c.6541539
Autor:
Mark R. Philips, Il-Jin Kim, Reyno Delrosario, Saumya R. Bollam, Peter M. K. Westcott, Hani Goodarzi, Olga K. Mirzoeva, Minh D. To, Wei-Ching Chen, Allan Balmain, Nora Bayani, Quan Tran
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature communications, vol 12, iss 1
The commonly mutated human KRAS oncogene encodes two distinct KRAS4A and KRAS4B proteins generated by differential splicing. We demonstrate here that coordinated regulation of both isoforms through control of splicing is essential for development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427008964cbd7475c096e5e574e7f68f
http://europepmc.org/articles/PMC8277813
http://europepmc.org/articles/PMC8277813
Autor:
Yun Rose Li, Kyle Halliwill, Eve Kandyba, Reyno Delrosario, Quan Tran, Nora Bayani, Di Wu, Olga Mirzoeva, Melissa McCreery Reeves, Mishu Islam, Laura Riva, Eric Bergstrom, John Digiovanni, Ludmil Alexandrov, Allan Balmain
Publikováno v:
Cancer Research. 82:2198-2198
An estimated 40% of all human cancers are suspected to be a result of modifiable risk factors such as obesity, high fat diet and chronic inflammation. Whole genome sequencing (WGS) of thousands of human tumors have revealed “mutational signatures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::584faafbd2fc50e90ba4922571dcf0c5
https://doi.org/10.1158/1538-7445.am2022-2198
https://doi.org/10.1158/1538-7445.am2022-2198
Autor:
Melissa Q. McCreery, Reyno Delrosario, Vincent Beuger, Christine E. Wong, Allan Balmain, Jonas Sjölund, Hio Chung Kang, Jost Seibler, Kyle D. Halliwill, Arnaud Jabouille, Atul Kumar, Phillips Y. Huang, Dennis J. Eastburn, Adam Sciambi, Eve Kandyba, Maurizio Pellegrino
Publikováno v:
Nature genetics
The G-protein-coupled receptors LGR4, LGR5 and LGR6 are Wnt signaling mediators, but their functions in squamous cell carcinoma (SCC) are unclear. Using lineage tracing in Lgr5-EGFP-CreERT2/Rosa26-Tomato and Lgr6-EGFP-CreERT2/Rosa26-Tomato reporter m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ff5047531efba3c1be8665ac8c5fb6
http://europepmc.org/articles/PMC5662105
http://europepmc.org/articles/PMC5662105
Autor:
Eve Kandyba, David A. Quigley, Jonas Sjölund, Reyno Delrosario, Di Wu, Phillips Y. Huang, Gillian L. Hirst, Kyle D. Halliwill, Atul Kumar, Christine E. Wong, Facundo G. Pelorosso, Allan Balmain
Publikováno v:
Cell reports, vol 16, iss 4
Cell Reports, Vol 16, Iss 4, Pp 1153-1165 (2016)
Cell Reports, Vol 16, Iss 4, Pp 1153-1165 (2016)
SummaryInherited germline polymorphisms can cause gene expression levels in normal tissues to differ substantially between individuals. We present an analysis of the genetic architecture of normal adult skin from 470 genetically unique mice, demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4976453a484fce1b9290af92b7d919f
https://doi.org/10.1016/j.celrep.2016.06.061
https://doi.org/10.1016/j.celrep.2016.06.061