Rat embryonic hippocampus and induced pluripotent stem cell derived cultured neurons recover from laser-induced subaxotomy

Autor: Selfridge, Aaron, Hyun, Nicholas, Chiang, Chai-Chun, Reyna, Sol M, Weissmiller, April M, Shi, Linda Z, Preece, Daryl, Mobley, William C, Berns, Michael W

Publikováno v: Neurophotonics, vol 2, iss 1

Axonal injury and stress have long been thought to play a pathogenic role in a variety of neurodegenerative diseases. However, a model for studying single-cell axonal injury in mammalian cells and the processes of repair has not been established. The

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https://escholarship.org/uc/item/25h141d7

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A γ-Secretase Inhibitor, but Not a γ-Secretase Modulator, Induced Defects in BDNF Axonal Trafficking and Signaling: Evidence for a Role for APP.

Autor: Weissmiller, April M., Natera-Naranjo, Orlangie, Reyna, Sol M., Pearn, Matthew L., Zhao, Xiaobei, Nguyen, Phuong, Cheng, Soan, Goldstein, Lawrence S. B., Tanzi, Rudolph E., Wagner, Steven L., Mobley, William C., Wu, Chengbiao

Publikováno v: PLoS ONE; Feb2015, Vol. 10 Issue 2, p1-24, 24p

Rat embryonic hippocampus and induced pluripotent stem cell derived cultured neurons recover from laser-induced subaxotomy.

Autor: Selfridge A; University of California , San Diego, Department of Bioengineering, 9500 Gilman Drive, La Jolla, California 92093, United States., Hyun N; University of California , San Diego, Department of Bioengineering, 9500 Gilman Drive, La Jolla, California 92093, United States., Chiang CC; University of California , San Diego, Department of Neurosciences, 9500 Gilman Drive, La Jolla, California 92093, United States., Reyna SM; University of California , San Diego, Department of Biomedical Sciences, 9500 Gilman Drive, La Jolla, California 92093, United States., Weissmiller AM; University of California , San Diego, Department of Neurosciences, 9500 Gilman Drive, La Jolla, California 92093, United States., Shi LZ; University of California , San Diego, Institute of Engineering in Medicine, 9500 Gilman Drive, La Jolla, California 92093, United States., Preece D; University of California , San Diego, Department of NanoEngineering, 9500 Gilman Drive La Jolla, California 92093, United States., Mobley WC; University of California , San Diego, Department of Neurosciences, 9500 Gilman Drive, La Jolla, California 92093, United States., Berns MW; University of California , San Diego, Department of Bioengineering, 9500 Gilman Drive, La Jolla, California 92093, United States ; University of California , San Diego, Institute of Engineering in Medicine, 9500 Gilman Drive, La Jolla, California 92093, United States ; University of California , Irvine, Beckman Laser Institute, 1002 Health Sciences Road, Irvine, California 92612, United States.

Publikováno v: Neurophotonics [Neurophotonics] 2015 Jan; Vol. 2 (1), pp. 015006. Date of Electronic Publication: 2015 Feb 13.