Determinants of SARS-CoV-2 receptor gene expression in upper and lower airways

Autor: Aliee, H, Massip, F, Qi, C, De Biase, MS, Van Nijnatten, J, Kersten, ETG, Kermani, NZ, Khuder, B, Vonk, JM, Vermeulen, RCH, U-BIOPRED study group, Cambridge Lung Cancer Early Detection Programme, INER-Ciencias Mexican Lung Program, NHLBI LungMAP Consortium, Neighbors, M, Tew, GW, Grimbaldeston, M, Ten Hacken, NHT, Hu, S, Guo, Y, Zhang, X, Sun, K, Hiemstra, PS, Ponder, BA, Mäkelä, MJ, Malmström, K, Rintoul, RC, Reyfman, PA, Theis, FJ, Brandsma, CA, Adcock, IM, Timens, W, Xu, CJ, Van den Berge, M, Schwarz, RF, Koppelman, GH, Nawijn, MC, Faiz, A

The recent outbreak of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), has led to a worldwide pandemic. One week after initial symptoms develop, a subset of patients progresses to se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::31fd356406714cc16e528a90640f00af
http://hdl.handle.net/10044/1/100864

Mitochondrial integrated stress response controls lung epithelial cell fate.

Autor: Han S; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA. shan@northwestern.edu., Lee M; Department of Life Science, Dongguk University-Seoul, Goyang-si, Republic of Korea., Shin Y; Department of Life Science, Dongguk University-Seoul, Goyang-si, Republic of Korea., Giovanni R; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA., Chakrabarty RP; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA., Herrerias MM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA., Dada LA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA., Flozak AS; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA., Reyfman PA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA., Khuder B; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA., Reczek CR; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA., Gao L; Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, Seville, Spain., Lopéz-Barneo J; Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, Seville, Spain., Gottardi CJ; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA., Budinger GRS; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA., Chandel NS; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA. nav@northwestern.edu.; Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA. nav@northwestern.edu.

Publikováno v: Nature [Nature] 2023 Aug; Vol. 620 (7975), pp. 890-897. Date of Electronic Publication: 2023 Aug 09.

A Novel MIP-1-Expressing Macrophage Subtype in BAL Fluid from Healthy Volunteers.

Autor: Reyfman PA; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Malsin ES; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Khuder B; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Joshi N; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Gadhvi G; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Flozak AS; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Carns MA; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Aren K; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Goldberg IA; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Kim S; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Alexander M; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Sporn PHS; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Misharin AV; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Budinger GRS; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Lam AP; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Hinchcliff M; Department of Internal Medicine, Section of Rheumatology, Allergy, and Immunology, Yale School of Medicine, New Haven, Connecticut., Gottardi CJ; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and., Winter DR; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois and.

Publikováno v: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2023 Feb; Vol. 68 (2), pp. 176-185.

Author Correction: Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice.

Autor: McElroy GS; Department of Medicine Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Chakrabarty RP; Department of Medicine Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., D'Alessandro KB; Department of Medicine Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Hu YS; Department of Medicine Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Vasan K; Department of Medicine Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Tan J; Department of Medicine Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Stoolman JS; Department of Medicine Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Weinberg SE; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Steinert EM; Department of Medicine Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Reyfman PA; Department of Medicine Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Singer BD; Department of Medicine Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Ladiges WC; Department of Comparative Medicine, University of Washington School of Medicine, Seattle, WA, USA., Gao L; Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, Seville, Spain.; Departamento de Fisiología Médica Y Biofísica, Facultad de Medicina, Universidad de Sevilla, Seville, Spain.; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain., Lopéz-Barneo J; Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, Seville, Spain.; Departamento de Fisiología Médica Y Biofísica, Facultad de Medicina, Universidad de Sevilla, Seville, Spain.; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain., Ridge K; Department of Medicine Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Budinger GRS; Department of Medicine Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Chandel NS; Department of Medicine Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. nav@northwestern.edu.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA. nav@northwestern.edu.

Publikováno v: Scientific reports [Sci Rep] 2022 May 17; Vol. 12 (1), pp. 8191. Date of Electronic Publication: 2022 May 17.

Determinants of expression of SARS-CoV-2 entry-related genes in upper and lower airways.

Autor: Aliee H; Institute of Computational Biology, Helmholtz Centre, Munich, Germany., Massip F; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany., Qi C; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.; Department of Pediatric Pulmonology and Pediatric Allergy, University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Groningen, the Netherlands., Stella de Biase M; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany., van Nijnatten J; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.; Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Respiratory Bioinformatics and Molecular Biology (RBMB), School of Life Sciences, University of Technology Sydney, Sydney, New South Wales, Australia., Kersten ETG; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.; Department of Pediatric Pulmonology and Pediatric Allergy, University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Groningen, the Netherlands., Kermani NZ; Department of computing, Data Science Institute, Imperial College London, London, UK., Khuder B; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Vonk JM; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Vermeulen RCH; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Division of Environmental Epidemiology (EEPI), Institute for Risk Assessment Science (IRAS), Utrecht University, Utrecht, The Netherlands., Neighbors M; OMNI Biomarker Development, Genentech Inc., South San Francisco, California, USA., Tew GW; Product Development Immunology, Infectious Disease & Opthalmology, Genentech Inc., South San Francisco, California, USA., Grimbaldeston MA; OMNI Biomarker Development, Genentech Inc., South San Francisco, California, USA., Ten Hacken NHT; Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Hu S; Department of statistics, University of Oxford, Oxford, UK., Guo Y; Department of computing, Data Science Institute, Imperial College London, London, UK., Zhang X; Department of computing, Data Science Institute, Imperial College London, London, UK., Sun K; Department of computing, Data Science Institute, Imperial College London, London, UK., Hiemstra PS; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., Ponder BA; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, UK., Mäkelä MJ; Department of Allergy, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Malmström K; Department of Allergy, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Rintoul RC; Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, UK.; Royal Papworth Hospital, Cambridge, UK., Reyfman PA; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Theis FJ; Institute of Computational Biology, Helmholtz Centre, Munich, Germany.; Department of Mathematics, Technical University of Munich, Munich, Germany., Brandsma CA; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Adcock IM; National Heart and Lung Institute, London, UK., Timens W; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Xu CJ; Research group Bioinformatics and Computational Genomics, Centre for Individualised Infection Medicine, CiiM, Hannover Medical School, Helmholtz Centre for Infection Research, Hannover, Germany.; Department of Gastroenterology, Hepatology and Endocrinology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover Medical School, Helmholtz Centre for Infection Research, Hannover, Germany.; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands., van den Berge M; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.; Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Schwarz RF; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany., Koppelman GH; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.; Department of Pediatric Pulmonology and Pediatric Allergy, University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Groningen, the Netherlands., Nawijn MC; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Faiz A; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.; Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Respiratory Bioinformatics and Molecular Biology (RBMB), School of Life Sciences, University of Technology Sydney, Sydney, New South Wales, Australia.

Publikováno v: Allergy [Allergy] 2022 Feb; Vol. 77 (2), pp. 690-694. Date of Electronic Publication: 2021 Nov 03.