Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Reyes Gonzalez Exposito"'
Autor:
David K. Lau, Caroline Fong, Faten Arouri, Lillian Cortez, Hannah Katifi, Reyes Gonzalez-Exposito, Muhammad Bilal Razzaq, Su Li, Aislinn Macklin-Doherty, Monica Arenas Hernandez, Michael Hubank, Charlotte Fribbens, David Watkins, Sheela Rao, Ian Chau, David Cunningham, Naureen Starling
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Dihydropyrimidine dehydrogenase (DPD) is a key enzyme in the metabolism of fluoropyrimidines. Variations in the encoding DPYD gene are associated with severe fluoropyrimidine toxicity and up-front dose reductions are recommended.
Externí odkaz:
https://doaj.org/article/8c4c528d564e402aa51ff80d19849ea5
Autor:
Reyes Gonzalez-Exposito, Maria Semiannikova, Beatrice Griffiths, Khurum Khan, Louise J. Barber, Andrew Woolston, Georgia Spain, Katharina von Loga, Ben Challoner, Radhika Patel, Michael Ranes, Amanda Swain, Janet Thomas, Annette Bryant, Claire Saffery, Nicos Fotiadis, Sebastian Guettler, David Mansfield, Alan Melcher, Thomas Powles, Sheela Rao, David Watkins, Ian Chau, Nik Matthews, Fredrik Wallberg, Naureen Starling, David Cunningham, Marco Gerlinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background The T cell bispecific antibody cibisatamab (CEA-TCB) binds Carcino-Embryonic Antigen (CEA) on cancer cells and CD3 on T cells, which triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cel
Externí odkaz:
https://doaj.org/article/ed3d536126fe414a9681258db65b3503
Autor:
Khurum Khan, Reyes Gonzalez-Exposito, David Cunningham, Dow-Mu Koh, Andrew Woolston, Louise Barber, Beatrice Griffiths, Kyriakos Kouvelakis, Vanessa Calamai, Monia Bali, Nasir Khan, Annette Bryant, Claire Saffery, Charles Dearman, Ruwaida Begum, Sheela Rao, Naureen Starling, David Watkins, Ian Chau, Chiara Braconi, Nicola Valeri, Marco Gerlinger, Nicos Fotiadis
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
BackgroundImage-guided tissue biopsies are critically important in the diagnosis and management of cancer patients. High-yield samples are also vital for biomarker and resistance mechanism discovery through molecular/genomic analyses.Patients and Met
Externí odkaz:
https://doaj.org/article/8e8b30f146d24efdaf18a98b32ab9eed
Autor:
Sabeeh‑ur‑Rehman Butt, Muhammad S Khan, Carmen Murias, Maria Reyes Gonzalez-Exposito, Hendrik-Tobias Arkenau, Anna Patrikidou
Publikováno v:
Annals of Urologic Oncology (2019)
As research focus in oncology has recently shifted to immunomodulation, the era of introduction of immunotherapeutic agents in the management of prostate cancer has just begun. With the success of checkpoint blockade drugs in certain advanced tumours
Externí odkaz:
https://doaj.org/article/e7565f81b586410fb1aa79859f130df3
Autor:
Hendrik-Tobias Arkenau, Sabeeh Butt, Maria Reyes Gonzalez-Exposito, Muhammad S Khan, Anna Patrikidou, C. Murias
Publikováno v:
Annals of Urologic Oncology (2019)
As research focus in oncology has recently shifted to immunomodulation, the era of introduction of immunotherapeutic agents in the management of prostate cancer has just begun. With the success of checkpoint blockade drugs in certain advanced tumours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f04961c6a5eeb91e3080728190d030
https://doi.org/10.32948/auo.2019.09.04
https://doi.org/10.32948/auo.2019.09.04
Autor:
Kyriakos Kouvelakis, Khurum Khan, Charles Dearman, Ian Chau, Annette Bryant, Sheela Rao, Louise J. Barber, Nicos Fotiadis, C. Saffery, Monia Bali, Reyes Gonzalez-Exposito, Naureen Starling, Dow-Mu Koh, Marco Gerlinger, Beatrice Griffiths, V. Calamai, Ruwaida Begum, David Watkins, David Cunningham, Nasir Khan, Chiara Braconi, Andrew Woolston, Nicola Valeri
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background Image-guided tissue biopsies are critically important in the diagnosis and management of cancer patients. High-yield samples are also vital for biomarker and resistance mechanism discovery through molecular/genomic analyses. Patients and M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f7214a366a5f59849508ffbf9e3e76
https://doi.org/10.3389/fonc.2020.01634
https://doi.org/10.3389/fonc.2020.01634
Autor:
Nasir Khan, Charles Dearman, C. Saffery, Beatrice Griffiths, Marco Gerlinger, Ian Chau, Andrew Woolston, David Cunningham, David Watkins, Reyes Gonzalez-Exposito, Naureen Starling, Nicos Fotiadis, V. Calamai, Chiara Braconi, Annette Bryant, Nicola Valeri, D-M. Koh, Monia Bali, Kyriakos Kouvelakis, Sheela Rao, Khurum Khan, Ruwaida Begum, Louise J. Barber
BackgroundImage guided tissue biopsies are critically important in diagnosis and management of cancer patients. High yield samples are also vital for biomarker and resistance mechanism discovery through molecular/genomic analyses.Patients and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5e8448df37a6ead2083f8208bb9679
https://doi.org/10.1101/2020.04.17.20065458
https://doi.org/10.1101/2020.04.17.20065458
Autor:
C. Fong, D.K.W. Lau, M.B. Razzaq, H. Katifi, F. Arouri, David Cunningham, Charlotte Fribbens, Ian Chau, Naureen Starling, Sheela Rao, A. Macklin-Doherty, L. Cortez, D. Watkins, Reyes Gonzalez-Exposito, S. Li
Publikováno v:
Annals of Oncology. 32:S559
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e53025fa60f0363c4013d2e912f56e73
https://doi.org/10.1016/j.annonc.2021.08.974
https://doi.org/10.1016/j.annonc.2021.08.974
Publikováno v:
Targeted Oncology. 11:479-487
Ramucirumab (IMC-1121B, LY3009806) is a fully human G1 monoclonal antibody that specifically targets vascular endotelial growth factor receptor 2 (VEGFR-2) with a substantially greater binding affinity than that of its natural ligands. Early clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14d4684bc429320df4b0d16598fc2a1
https://doi.org/10.1007/s11523-016-0419-8
https://doi.org/10.1007/s11523-016-0419-8
Autor:
Marco Gerlinger, Andrew Wotherspoon, Georgia Spain, Romana Ranftl, Nasir Khan, Isma Rana, Ian Chau, Andrew Furness, David Cunningham, Yatish Patil, Matthew N. Davies, Katharina von Loga, Thomas Powles, Louise J. Barber, Francesco Sclafani, Naureen Starling, Anguraj Sadanandam, N. Fotiadis, Kyriakos Kouvelakis, Clare Peckitt, David Watkins, Ruwaida Begum, Janet Thomas, Khurum Khan, Andrew Woolston, Sebastian Guettler, Annette Bryant, Sergio A. Quezada, Teresa Marafioti, Sonia Mansukhani, Beatrice Griffiths, Reyes Gonzalez Exposito, Fernando Calvo, Sheela Rao
Anti-epidermal growth factor receptor (EGFR) antibodies (anti-EGFR-Ab) are effective in a subgroup of patients with metastatic colorectal cancer (CRC). We applied genomic and transcriptomic analyses to biopsies from 35 RAS wild-type CRCs treated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce37b389c6148fb052e08b06147c138f
https://doi.org/10.1101/448076
https://doi.org/10.1101/448076