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pro vyhledávání: '"Rey A. Panettieri"'
Autor:
Rey A. Panettieri, Mukesh K. Jain, Xiaozhu Huang, Kiriko Masuno, Saptarsi M. Haldar, Darwin Jeyaraj, Anthony N. Gerber, Christina M. Mailloux
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 45:642-649
Glucocorticoids (GCs), which activate GC receptor (GR) signaling and thus modulate gene expression, are widely used to treat asthma. GCs exert their therapeutic effects in part through modulating airway smooth muscle (ASM) structure and function. How
Publikováno v:
Journal of Biological Chemistry. 282:15366-15375
Interleukin-6 (IL-6) is a proinflammatory cytokine up-regulated by rhinovirus infection during acute exacerbations of asthma and chronic obstructive pulmonary disease. The role of IL-6 during exacerbations is unclear; however, it is believed IL-6 cou