Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rey A. L. Sia"'
Autor:
Kathryn Wershing, Deanna R Pedeville, Elaine A. Sia, Christina Seger, Christopher T Prevost, Rey A. L. Sia, Nicole Peris
Publikováno v:
Current Genetics. 64:199-214
Mitochondria are dynamic organelles that fuse and divide. These changes alter the number and distribution of mitochondrial structures throughout the cell in response to developmental and metabolic cues. We have demonstrated that mitochondrial fission
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c6b884f310dd40248dad6497a9ec84
https://doi.org/10.1007/s00294-017-0717-4
https://doi.org/10.1007/s00294-017-0717-4
Autor:
Daniel F Quintana, Lidza Kalifa, Garry L Coles, Laura K Schiraldi, Rey A. L. Sia, Naina Phadnis, Elaine A. Sia
Publikováno v:
Genetics. 190:951-964
Mitochondrial DNA (mtDNA) deletions are associated with sporadic and inherited diseases and age-associated neurodegenerative disorders. Approximately 85% of mtDNA deletions identified in humans are flanked by short directly repeated sequences; howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d97cfe295486fc4d126ed92c272534
https://doi.org/10.1534/genetics.111.138214
https://doi.org/10.1534/genetics.111.138214
Autor:
Joseph Heitman, M. Cristina Cruz, Hengming Ke, Maria E. Cardenas, Deborah S. Fox, Rey A. L. Sia, Gary M. Cox
Publikováno v:
Molecular Microbiology. 39:835-849
Calcineurin is a Ca2+–calmodulin-regulated protein phosphatase that is the target of the immunosuppressive drugs cyclosporin A and FK506. Calcineurin is a heterodimer composed of a catalytic A and a regulatory B subunit. In previous studies, the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe2091b766408ebeab6fb26c56f7e3e0
https://doi.org/10.1046/j.1365-2958.2001.02295.x
https://doi.org/10.1046/j.1365-2958.2001.02295.x
Publikováno v:
Fungal Genetics and Biology. 29:153-163
Cryptococcus neoformans is an opportunistic human pathogenic fungus with a defined sexual cycle. Clinical and environmental isolates of C. neoformans are haploid, and the diploid stage of the lifecycle is thought to be transient and unstable. In cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826a212492bd554e26710a360d5f5057
https://doi.org/10.1006/fgbi.2000.1192
https://doi.org/10.1006/fgbi.2000.1192
Publikováno v:
Infection and Immunity. 68:982-985
The calcineurin gene was cloned and disrupted in serotype D strains of Cryptococcus neoformans . Serotype A and serotype D calcineurin mutants were inviable at 37°C and avirulent in mice, whereas only serotype A mutants were cation stress sensitive.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3ad3f18ac81e177c526b81263e19cb
https://doi.org/10.1128/iai.68.2.982-985.2000
https://doi.org/10.1128/iai.68.2.982-985.2000
Publikováno v:
Molecular and Cellular Biology. 19:5981-5990
The morphogenesis checkpoint in budding yeast delays cell cycle progression in G(2) when the actin cytoskeleton is perturbed, providing time for cells to complete bud formation prior to mitosis. Checkpoint-induced G(2) arrest involves the inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6691dbf5ebe781a86235efe755624cfa
https://doi.org/10.1128/mcb.19.9.5981
https://doi.org/10.1128/mcb.19.9.5981
Publikováno v:
The EMBO Journal. 17:6678-6688
In the budding yeast Saccharomyces cerevisiae, a cell cycle checkpoint coordinates mitosis with bud formation. Perturbations that transiently depolarize the actin cytoskeleton cause delays in bud formation, and a 'morphogenesis checkpoint' detects th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8ed1130382bba733ffb491bc4834a5
https://doi.org/10.1093/emboj/17.22.6678
https://doi.org/10.1093/emboj/17.22.6678
Publikováno v:
The Journal of Cell Biology
A morphogenesis checkpoint in budding yeast delays cell cycle progression in response to perturbations of cell polarity that prevent bud formation (Lew, D.J., and S.I. Reed. 1995. J. Cell Biol. 129:739– 749). The cell cycle delay depends upon the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0136710cb9a78b1211443ba51c9241fd
https://doi.org/10.1083/jcb.142.6.1487
https://doi.org/10.1083/jcb.142.6.1487
Publikováno v:
Genes & Development. 12:2587-2597
Ubiquitin-mediated proteolysis controls the abundance of many cell cycle regulatory proteins. Recent work in Saccharomyces cerevisiae suggests that a complex consisting of Cdc53, Skp1, and a third component known as an F-box protein (termed SCF) in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cdcc7768657a806ebc3f4d8c7657c72
https://doi.org/10.1101/gad.12.16.2587
https://doi.org/10.1101/gad.12.16.2587
Autor:
Aaron P. Mitchell, Rey A. L. Sia
Publikováno v:
Molecular and Cellular Biology. 15:5279-5287
Ime2p is a protein kinase that is expressed only during meiosis in Saccharomyces cerevisiae. Ime2p stimulates early, middle, and late meiotic gene expression and down-regulates expression of IME1, which specifies an activator of early meiotic genes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d4f5d6694f66b0ee5dc53022f92594
https://doi.org/10.1128/mcb.15.10.5279
https://doi.org/10.1128/mcb.15.10.5279