A randomized, controlled trial of remacemide for motor fluctuations in Parkinson's disease

Autor: Lawrence Elmer, McGuire D, Janis M. Miyasaki, Pierre N. Tariot, Cynthia L. Comella, Rajesh Pahwa, S. Schuman, Margaret C. Lannon, James W. Tetrud, Wiener W, Christopher Cox, Oksana Suchowersky, Wratni E, Lucia M. Blasucci, Chase T, Greenamyre Jt, Karen Hodgeman, Deleo A, Michael P. McDermott, Carrion A, Panniset M, Paula D. Ryan, Robert A. Hauser, Johnston L, Bateman-Rodriguez D, Amy Colcher, Baker D, Mistura K, Andrew Siderowf, W.R. Wayne Martin, Peggy Gray, Constance Orme, Jeffrey Friedlander, Charles H. Adler, Dilllon S, Stanley Fahn, Eric Siemers, David Grimes, Lauren Seeberger, M. Brewer, Colleen Dingmann, Frey J, Holdich T, Cooper J, Mark Stacy, Stewart A. Factor, Daniel Tarsy, Kennedy L, McCree L, Mary Lloyd, J. B. Penney, Lisa Gauger, Pantella C, Arthur Watts, Kenneth Marek, John P. Hammerstad, Matthews M, Kimberly Janko, Diane Brown, Denni Day, McDermott J, Sulimowicz K, Ruzicka D, Marsha Tennis, Bardram K, Joann Belden, Madaline B. Harrison, Blair Ford, Davies R, Mark F. Lew, Alderfer, Jennifer Mazurkiewicz, Elise Kayson, Broshjeit S, Rexo L, Andrew Feigin, Craun Am, Cha Jh, C. Stone, Stephanie Newman, Nirupama Laroia, Jean Hall, Ira Shoulson, Peter A LeWitt, Read B, Robert L. Rodnitzky, Danna Jennings, Judith Dobson, Lang A, Florack M, Nobel R, Steven R. Schwid, Leventhal C, A. L. Lafontaine, Nancy Pearson, Lawrence N. Shulman, Rothenburgh K, Rost E, Locke B, Cindy Casaceli

Publikováno v: Neurology. 56:455-462

Background Preclinical studies suggest that glutamate antagonists help ameliorate motor fluctuations in patients with PD treated with levodopa. Methods In a multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-ranging study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d568a8ad50ad99173f553a65cfb0dde5
https://doi.org/10.1212/wnl.56.4.455