Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rex E. Martin"'
Autor:
Samuel Kelly, Thomas W. Gardner, Rex E Martin, Xianlin Han, Alfred H. Merrill, Mark Kester, Todd E. Fox, Robert E. Anderson
Publikováno v:
Diabetes. 55:3573-3580
Dysregulated sphingolipid metabolism causes neuronal cell death and is associated with insulin resistance and diseases. Thus, we hypothesized that diabetes-induced changes in retinal sphingolipid metabolism may contribute to neuronal pathologies in d
Autor:
William Meyer, Robert C. Gaston, Bernard F Fuemmeler, Rex E Martin, Stacy L. Anderson, T. David Elkin, Frank A. Holloway, Michael O Wollan
Publikováno v:
Neuropsychiatric Disease and Treatment
Specific memory deficits, reduced intellectual processing speed, and a variety of social and behavioral problems have been implicated as long-term effects of cranial radiation therapy (CRT). These deficits are thought to be related to changes in brai
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 67:105-111
Docosahexaenoic acid (22:6n-3) is highly enriched in the retina. To determine if retinal cells take up and metabolize fatty acids in a specific manner, retinas from Rana pipiens were incubated for 3 h with an equimolar mixture of tritiated 22:6n-3, a
Autor:
Rex E Martin
Publikováno v:
Journal of Neuroscience Research. 54:805-813
Docosahexaenoic acid (DHA) accumulates in nerve growth cones (NGC) during perinatal development and it is neuroprotective in ischemia. Because the phospholipases A2 (PLA2) are present in NGC and these enzymes function in both ischemia and long-term p
Publikováno v:
Journal of Neurovirology. 2:127-135
This research examines changes that occur in neurons during corneal herpes simplex virus (HSV-1) infection and focuses on the nerve growth associated protein GAP-43. Cornea and trigeminal ganglion (TG) of New Zealand white rabbits were examined after
Publikováno v:
The Journal of Nutritional Biochemistry. 5:151-160
Docasahexaenoic acid is an essential fatty acid enriched in lipids of photoreceptor, synaptic, and nerve growth cone membranes. [ 3 H]docosahexaenoic acid was intraperitoneally injected in 5-day-old and 14-day-old mouse pups, and the labeling time co
Autor:
Nicolas G. Bazan, Rex E. Martin
Publikováno v:
Experimental Eye Research. 55:307-314
We used dual-wavelength fluorescence microscopy and monoclonal antibodies to growth-associated protein (GAP-43) and nerve cell adhesion molecule (N-CAM) to identify these proteins in nerve fibers of normal rat and rabbit corneas. Overlapping immunore
Autor:
Rex E, Martin, Steven J, Fliesler, Richard S, Brush, Michael J, Richards, Stephen A, Hopkins, Robert E, Anderson
Publikováno v:
Molecular vision. 11
Retinal degenerations and diets low in n-3 fatty acids are associated with decreased docosahexaenoic acid (22:6n-3) in retina and plasma and with sterol abnormalities in retina and sperm. Using wild type (WT) and transgenic rats with P23H and S334ter
Publikováno v:
Investigative ophthalmologyvisual science. 46(4)
PURPOSE. In recent years, detergent-resistant membranes (DRMs) have been isolated in in vitro models of lipid rafts, from photoreceptor outer segments (ROS), and the localization of a specific complement of photoreceptor proteins has been demonstrate
Autor:
Rex E, Martin, Isabelle, Ranchon-Cole, Richard S, Brush, Clint R, Williamson, Steven A, Hopkins, Feng, Li, Robert E, Anderson
Publikováno v:
Molecular vision. 10
The n-3 polyunsaturated fatty acids (PUFA) facilitate retinal development and function. Rats carrying transgenes with P23H and S334ter rhodopsin mutations lose their photoreceptors and have lower levels of 22:6n-3 in rod photoreceptor outer segments