Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Rex B Mowat"'
Autor:
Brendan J Guercio, Sui Zhang, Donna Niedzwiecki, Yanping Li, Ana Babic, Vicente Morales-Oyarvide, Leonard B Saltz, Robert J Mayer, Rex B Mowat, Renaud Whittom, Alexander Hantel, Al Benson, Daniel Atienza, Michael Messino, Hedy Kindler, Alan Venook, Shuji Ogino, Emilie S Zoltick, Meir Stampfer, Kimmie Ng, Kana Wu, Walter C Willett, Edward L Giovannucci, Jeffrey A Meyerhardt, Charles S Fuchs
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0199244 (2018)
PurposeObservational studies have demonstrated increased colon cancer recurrence and mortality in states of excess energy balance, as denoted by factors including sedentary lifestyle, diabetes, increased dietary glycemic load, and increased intake of
Externí odkaz:
https://doaj.org/article/fb2d317d032846f1bcddf84f96858c83
Autor:
Michael A Fuchs, Kaori Sato, Donna Niedzwiecki, Xing Ye, Leonard B Saltz, Robert J Mayer, Rex B Mowat, Renaud Whittom, Alexander Hantel, Al Benson, Daniel Atienza, Michael Messino, Hedy Kindler, Alan Venook, Shuji Ogino, Kana Wu, Walter C Willett, Edward L Giovannucci, Jeffrey A Meyerhardt
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99816 (2014)
BACKGROUND:In colon cancer patients, obesity, sedentary lifestyle, and high dietary glycemic load have been associated with increased risk of cancer recurrence. High sugar-sweetened beverage intake has been associated with obesity, diabetes, and card
Externí odkaz:
https://doaj.org/article/1c91194260644e9281cd6649cc96e240
Autor:
Guila Delouya, Marvin Feldman, Jennifer Moughan, Rex B. Mowat, Yuhchyau Chen, Rakesh Gaur, Samir Narayan, John P. Hayes, William F. Regine, Joshua E. Meyer, John P. Hoffman, David L. Sherr, Edgar Ben-Josef, Thomas A. DiPetrillo, Howard Safran, Christopher H. Crane, Richard A. Peterson, Marsha Reyngold, Kathryn Winter, John H. Suh, Michael G. Haddock, Kathleen J. Yost, Ross A. Abrams, Ivan L. Kessel
Publikováno v:
The Oncologist. 25:e477-e483
Background Several registry-based analyses suggested a survival advantage for married versus single patients with pancreatic cancer. The mechanisms underlying the association of marital status and survival are likely multiple and complex and, therefo
Autor:
Kostandinos Sideras, David W Hillman, Karthik Giridhar, Brenda F Ginos, Richard C Tenglin, Heshan Liu, Beiyun Chen, Winston Tan, Gerald G Gross, Rex B Mowat, Amylou C Dueck, Edith A Perez, Alvaro Moreno-Aspitia
Publikováno v:
The oncologist.
Background Anthracycline use in metastatic breast cancer (MBC) is hindered by cumulative exposure limits and risk of cardiotoxicity. Pixantrone, a novel aza-anthracenedione with structural similarities to mitoxantrone and anthracyclines, is theorized
Autor:
R. Robb, Thomas A. DiPetrillo, Edgar Ben-Josef, William F. Regine, David A. Bush, Terence M. Williams, Cynthia Timmers, Han Jo Kim, N.C. Leasure, Rex B. Mowat, Jennifer Moughan, M. Fromm, Samir Narayan, Chandan Guha, J.M. Koenig
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 111:S145-S146
PURPOSE/OBJECTIVE(S) SMAD4 (DPC4) is a transcription factor that mediates TGF-beta signal transduction and is mutationally in-activated in about one-third of pancreatic cancer (PC). Studies have suggested that SMAD4 loss is associated with a higher r
Autor:
R. Robb, Edgar Ben-Josef, J.M. Koenig, William F. Regine, N.C. Leasure, Samir Narayan, T.A. DiPetrillo, M. Fromm, Chandan Guha, Cynthia Timmers, David A. Bush, Kathryn Winter, Terence M. Williams, Han Jo Kim, Rex B. Mowat
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 111:S146-S147
Purpose/objective(s) Laboratory experiments show that activation of β-catenin signaling promotes pancreatic cancer (PC) growth, but studies addressing its prognostic value in patients (pts) are scarce and with conflicting results. This question has
Autor:
Robert J. Mayer, Donna Niedzwiecki, Sui Zhang, Alexander Hantel, Eric G. Wolfe, Shuji Ogino, Al B. Benson, Leonard B. Saltz, Daniel Atienza, Chao Ma, Michael J. Messino, Alan P. Venook, Rex B. Mowat, Hedy L. Kindler, Seohyuk Lee, Charles S. Fuchs, Cary P. Gross, Fang-Shu Ou, Melinda L. Irwin, Jeffrey A. Meyerhardt, Renaud Whittom
Publikováno v:
JNCI Cancer Spectrum
Background Disparities in colon cancer outcomes have been reported across race and socioeconomic status, which may reflect, in part, access to care. We sought to assess the influences of race and median household income (MHI) on outcomes among colon
Autor:
Renaud Whittom, Al B. Benson, Robert J. Mayer, Edward Giovannucci, Michael J. Messino, Brian C. Mullen, Donna Niedzwiecki, Charles S. Fuchs, Daniel Atienza, Fang-Shu Ou, Alexander Hantel, Leonard B. Saltz, Sui Zhang, En Cheng, Erin L. Van Blarigan, Hedy L. Kindler, Jeffrey A. Meyerhardt, Rex B. Mowat, Kimmie Ng
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Background: Hyperinsulinemia is considered to be important in the development of colon cancer, but few studies have investigated the associations of hyperinsulinemia with colon cancer survival via dietary scores. Methods: Empirical dietary index for
Autor:
Edward Giovannucci, Renaud Whittom, Kimmie Ng, Alan P. Venook, Rex B. Mowat, Al B. Benson, Daniel Atienza, Walter C. Willett, Leonard B. Saltz, Alexander Hantel, Michael J. Messino, Hedy L. Kindler, Robert J. Mayer, Sui Zhang, Ying Bao, Xing Ye, Shuji Ogino, Kana Wu, Charles S. Fuchs, Jeffrey A. Meyerhardt, Donna Niedzwiecki, Temidayo Fadelu
Publikováno v:
Journal of Clinical Oncology
PurposeObservational studies have reported increased colon cancer recurrence and mortality in patients with states of hyperinsulinemia, including type 2 diabetes, obesity, sedentary lifestyle, and high glycemic load diet. Nut intake has been associat
Autor:
Yaacov Richard Lawrence, Anthony M. Magliocco, Talia Golan, Adam P. Dicker, Thomas A. DiPetrillo, Chandan Guha, William F. Regine, Jeffry P. Simko, Alexander C. Klimowicz, Christopher H. Crane, Jennifer Moughan, Kathryn Winter, William Small, Rex B. Mowat
Publikováno v:
Cancer. 124:491-498
BACKGROUND The majority of patients with pancreatic cancer who undergo curative resection experience rapid disease recurrence. In previous small studies, high expression of the mismatch-repair protein mutL protein homolog 1 (MLH1) in pancreatic cance