Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rex A, Kerr"'
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Organisms undergo a variety of characteristic changes as they age, suggesting a substantial commonality in the mechanistic basis of aging. Experiments in model organisms have revealed a variety of cellular systems that impact lifespan, but technical
Externí odkaz:
https://doaj.org/article/3d576617ebdd4db1899e581561ab443e
Publikováno v:
Cell Reports, Vol 19, Iss 3, Pp 441-450 (2017)
Summary: The goal of aging research is to extend healthy, active life. For decades, C. elegans daf-2 insulin/insulin-like growth factor 1 (IGF-1) receptor mutants have served as a model for extended lifespan and youthfulness. However, a recent report
Externí odkaz:
https://doaj.org/article/b0c62b04c91a4944a95b80687bb12c5f
Publikováno v:
Frontiers in aging. 3
Organisms undergo a variety of characteristic changes as they age, suggesting a substantial commonality in the mechanistic basis of aging. Experiments in model organisms have revealed a variety of cellular systems that impact lifespan, but technical
Autor:
Tomoko Ohyama, Tihana Jovanic, Gennady Denisov, Tam C Dang, Dominik Hoffmann, Rex A Kerr, Marta Zlatic
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71706 (2013)
All organisms react to noxious and mechanical stimuli but we still lack a complete understanding of cellular and molecular mechanisms by which somatosensory information is transformed into appropriate motor outputs. The small number of neurons and ex
Externí odkaz:
https://doaj.org/article/bae9944bfa224897b10c0ef39f483e01
Autor:
Trevor J Wardill, Tsai-Wen Chen, Eric R Schreiter, Jeremy P Hasseman, Getahun Tsegaye, Benjamin F Fosque, Reza Behnam, Brenda C Shields, Melissa Ramirez, Bruce E Kimmel, Rex A Kerr, Vivek Jayaraman, Loren L Looger, Karel Svoboda, Douglas S Kim
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77728 (2013)
Fluorescent protein-based sensors for detecting neuronal activity have been developed largely based on non-neuronal screening systems. However, the dynamics of neuronal state variables (e.g., voltage, calcium, etc.) are typically very rapid compared
Externí odkaz:
https://doaj.org/article/260c05b0e92b4cd0a03c4417df7ccb10
Autor:
Raja C. Hayek, Rex C. Kerr, Syrus C. Nemat-Nasser, Brian Sagi, Robert Hecht-Nielsen, Christopher C. Downing
Publikováno v:
Neural Computation. 13:1575-1602
We present a new approach to the cocktail party problem that uses a cortronic artificial neural network architecture (Hecht-Nielsen, 1998) as the front end of a speech processing system. Our approach is novel in three important respects. First, our m
Autor:
Rex A, Kerr, William R, Schafer
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 351
Optical methods provide a noninvasive way to monitor calcium transients in Caenorhabditis elegans. Imaging techniques are particularly appealing in C. elegans because worms are optically transparent and can be imaged while fully intact. Furthermore,