Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Review|Basic"'
Publikováno v:
European Journal of Immunology
T cells are central players of the adaptive immune system by protecting us from recurring infections and by killing malignant cells. Protective T cell responses rely on the concerted production of effector molecules such as cytolytic mediators, granz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54026917243596a7ddebfebe6a6bc3ce
http://www.scopus.com/inward/record.url?scp=85109986741&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85109986741&partnerID=8YFLogxK
Autor:
Timur Tuganbaev, Kenya Honda
Publikováno v:
European Journal of Immunology
Fundamental asymmetries between the host and its microbiome in enzymatic activities and nutrient storage capabilities have promoted mutualistic adaptations on both sides. As a result, the enteric immune system has evolved so as not to cause a zero‐
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f6aa06a7bb783b50b727945b4283864
https://doi.org/10.1002/eji.202049065
https://doi.org/10.1002/eji.202049065
Publikováno v:
European Journal of Immunology
The functional avidity (FA) of cytotoxic CD8 T cells impacts strongly on their functional capabilities and correlates with protection from infection and cancer. FA depends on TCR affinity, downstream signaling strength, and TCR affinity‐independent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e78c5e0b495d663444b6e600c32ef26
https://doi.org/10.1002/eji.202049016
https://doi.org/10.1002/eji.202049016
Publikováno v:
European Journal of Immunology
Coronaviruses (CoVs) represent enveloped, ss RNA viruses with the ability to infect a range of vertebrates causing mainly lung, CNS, enteric, and hepatic disease. While the infection with human CoV is commonly associated with mild respiratory symptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd342842f4d983e8e2cbf8a03979681
https://doi.org/10.1002/eji.202048984
https://doi.org/10.1002/eji.202048984
Publikováno v:
European Journal of Immunology
The development of the human immune system during embryonic and fetal life has historically been difficult to research due to limited access to human tissue. Experimental animal models have been widely used to study development but cellular and molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::277c2fbcddacf9c76db67c13e1368f92
https://doi.org/10.1002/eji.202048769
https://doi.org/10.1002/eji.202048769
Autor:
Noëlla Lopes, Bruno Silva-Santos
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
European Journal of Immunology
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
European Journal of Immunology
© 2020 The Authors. European Journal of Immunology published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution License.
γδ T cells can display a plethora of immune functions, but recent stud
γδ T cells can display a plethora of immune functions, but recent stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc3e6ab08641a25b0034c3bf09767fe
https://doi.org/10.1002/eji.201948402
https://doi.org/10.1002/eji.201948402
Publikováno v:
European Journal of Immunology
The nuclear receptor Nur77 is expressed in a multitude of tissues, regulating cell differentiation and homeostasis. Dysregulation of Nur77 signaling is associated with cancer, cardiovascular disease, and disorders of the CNS. The role of Nur77 in T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c8d86bce0313fa63bd627ebdf40280
https://doi.org/10.1002/eji.202048869
https://doi.org/10.1002/eji.202048869
Publikováno v:
European Journal of Immunology
C‐type lectin receptors (CLRs) are essential for multicellular existence, having diverse functions ranging from embryonic development to immune function. One subgroup of CLRs is the Dectin‐1 cluster, comprising of seven receptors including MICL,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c7c7b3c223847289adb92d511812a1
http://europepmc.org/articles/PMC6916577
http://europepmc.org/articles/PMC6916577
Publikováno v:
European Journal of Immunology, 51(8), 1911-1920. WILEY
European Journal of Immunology
European Journal of Immunology
Immunotherapy targeting the Programmed Death (PD‐1) receptor/ligand (L) “checkpoint” rapidly gains ground in the treatment of many cancer types. To increase treatment scope and efficacy, predictive biomarkers and rational selection of co‐trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48544875d05fc3bf2ae73ae7aa441957
http://hdl.handle.net/1887/3197171
http://hdl.handle.net/1887/3197171
Autor:
Luís Almeida, Bart Everts
Publikováno v:
European Journal of Immunology
European Journal of Immunology, 51(7), 1628-1640. WILEY
European Journal of Immunology, 51(7), 1628-1640. WILEY
In recent years there have been major advances in our understanding of the role of free fatty acids (FAs) and their metabolism in shaping the functional properties of macrophages and DCs. This review presents the most recent insights into how cell in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c261b7cb73dee3b60a3fa62a080a6b
https://hdl.handle.net/1887/3214691
https://hdl.handle.net/1887/3214691