Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Revathi, Balasubramanian"'
Autor:
Revathi Balasubramanian, Krishnakumar Kizhatil, Taibo Li, Nicholas Tolman, Aakriti Bhandari, Graham Clark, Violet Bupp-Chickering, Ruth A Kelly, Sally Zhou, John Peregrin, Marina Simón, Christa Montgomery, W Daniel Stamer, Jiang Qian, Simon WM John
Publikováno v:
eLife, Vol 13 (2024)
Schlemm’s canal (SC) is central in intraocular pressure regulation but requires much characterization. It has distinct inner and outer walls, each composed of Schlemm’s canal endothelial cells (SECs) with different morphologies and functions. Rec
Externí odkaz:
https://doaj.org/article/51d832f1ed604c4ab2be5f5c1d392221
Autor:
Nicholas G. Tolman, Revathi Balasubramanian, Danilo G. Macalinao, Alison L. Kearney, Katharine H. MacNicoll, Christa L. Montgomery, Wilhelmine N. de Vries, Ian J. Jackson, Sally H. Cross, Krishnakumar Kizhatil, K. Saidas Nair, Simon W. M. John
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 2 (2021)
Variants in the LIM homeobox transcription factor 1-beta (LMX1B) gene predispose individuals to elevated intraocular pressure (IOP), a key risk factor for glaucoma. However, the effect of LMX1B mutations varies widely between individuals. To better u
Externí odkaz:
https://doaj.org/article/c6b3c570e59e4dcfbb215df5e8ffb694
Autor:
Glyn Chidlow, Simon W. M. John, Jeffrey M. Harder, Evangelia Daskalaki, Peter A. Williams, Nicole E. Foxworth, Craig E. Wheelock, Tionna B Ouellette, Robert J Casson, Chelsea Guymer, John P. M. Wood, Chi Zhang, Brynn H Cardozo, Christa Montgomery, Kelly E Deering, Revathi Balasubramanian
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Age-related bioenergetic insufficiency increases the vulnerability of retinal ganglion cells to intraocular pressure during glaucoma pathogenesis. This paper addresses these relationships and provides a deeper understanding of this commo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f090f275df2db2821fdf8d2ab659d2f
http://europepmc.org/articles/PMC7776900
http://europepmc.org/articles/PMC7776900
Autor:
Nefeli Slavi, Revathi Balasubramanian, Melissa Ann Lee, Michael Liapin, Rachel Oaks-Leaf, John Peregrin, Anna Potenski, Carol Marie Troy, Margaret Elizabeth Ross, Eloisa Herrera, Stylianos Kosmidis, Simon William Maxwell John, Carol Ann Mason
Publikováno v:
Neuron.
In albinism, aberrations in the ipsi-/contralateral retinal ganglion cell (RGC) ratio compromise the functional integrity of the binocular circuit. Here, we focus on the mouse ciliary margin zone (CMZ), a neurogenic niche at the embryonic peripheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575b03183ee56ecbb154eb5f804cd9ed
https://pubmed.ncbi.nlm.nih.gov/36351424
https://pubmed.ncbi.nlm.nih.gov/36351424
Autor:
Diego F. Buenaventura, Bruna Lopes da Costa, Xuanyu Min, Xin Zhang, Neoklis Makrides, Fen Wang, Quentin Lo Giudice, Revathi Balasubramanian, Michael Bouaziz, Yingyu Mao, Chenqi Tao, Peter M Quinn, Pierre J. Fabre, Liang Ma, Stephen H. Tsang, Qian Wang, Karina Polanco, John Peregrin
Publikováno v:
Science Advances
Description
FGF and Wnt signaling controls the phase transition of the ocular fate.
The developing vertebrate eye cup is partitioned into the neural retina (NR), the retinal pigmented epithelium (RPE), and the ciliary margin (CM). By single
FGF and Wnt signaling controls the phase transition of the ocular fate.
The developing vertebrate eye cup is partitioned into the neural retina (NR), the retinal pigmented epithelium (RPE), and the ciliary margin (CM). By single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b8984f2e83db8e29be607c89c8dca6
https://doi.org/10.1126/sciadv.abj9846
https://doi.org/10.1126/sciadv.abj9846
Autor:
Bruna Lopes da Costa, Qian Wang, Fen Wang, Xuanyu Min, Neoklis Makrides, Diego F. Buenaventura, Revathi Balasubramanian, Pierre J. Fabre, Liang Ma, Peter M Quinn, Chenqi Tao, Yingyu Mao, Michael Bouaziz, Stephen H. Tsang, Karina Polanco, John Peregrin, Quentin Lo Giudice, Xin Zhang
The developing vertebrate eye cup is partitioned into the neural retina (NR), the retinal pigmented epithelium (RPE) and the ciliary margin (CM). By single cell analysis, we showed that a gradient of FGF signaling regulates demarcation and subdivisio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10890cb137a1c46984d96134f8cc20db
https://doi.org/10.1101/2021.08.12.455556
https://doi.org/10.1101/2021.08.12.455556
Autor:
Krishnakumar Kizhatil, Danilo G. Macalinao, Sally H. Cross, Wilhelmine N. de Vries, Ian J. Jackson, K. Saidas Nair, Nicholas G. Tolman, Alison L. Kearney, Christa L. Montgomery, Katharine H. MacNicoll, Revathi Balasubramanian, Simon W. M. John
Publikováno v:
Tolman, NG, Balasubramanian, R, Macalinao, D G, Kearney, A L, MacNicoll, KH, Montgomery, C L, de Vries, WN, Jackson, I J, Cross, S, Kizhatil, K, Nair, KS & John, SWM 2021, ' Genetic background modifies vulnerability to glaucoma related phenotypes in Lmx1b mutant mice ', Disease Models and Mechanisms . https://doi.org/10.1242/dmm.046953
Disease Models & Mechanisms, Vol 14, Iss 2 (2021)
Disease Models & Mechanisms, Vol 14, Iss 2 (2021)
Variants in the LIM homeobox transcription factor 1-beta (LMX1B) gene predispose individuals to elevated intraocular pressure (IOP), a key risk factor for glaucoma. However, the effect of LMX1B mutations varies widely between individuals. To better u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e75d0cad79578c4d4f4a32c26eefdf6
https://doi.org/10.1242/dmm.046953
https://doi.org/10.1242/dmm.046953
Autor:
Nicholas G, Tolman, Revathi, Balasubramanian, Danilo G, Macalinao, Alison L, Kearney, Katharine H, MacNicoll, Christa L, Montgomery, Wilhelmine N, de Vries, Ian J, Jackson, Sally H, Cross, Krishnakumar, Kizhatil, K Saidas, Nair, Simon W M, John
Publikováno v:
Disease Models & Mechanisms
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Variants in the LIM homeobox transcription factor 1-beta (LMX1B) gene predispose individuals to elevated intraocular pressure (IOP), a key risk factor for glaucoma. However, the effect of LMX1B mutations varies widely between individuals. To better u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c342cda45eb1b5f9f6dc046d7c6df31d
https://pubmed.ncbi.nlm.nih.gov/33462143
https://pubmed.ncbi.nlm.nih.gov/33462143
Autor:
Revathi Balasubramanian, Xin Zhang
Publikováno v:
Seminars in Cell & Developmental Biology. 53:94-100
Fibroblast growth factors (FGFs) have long been attributed to influence morphogenesis in embryonic development. Signaling by FGF morphogen encodes positional identity of tissues by creating a concentration gradient over the developing embryo. Various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aad09d9b64b3b644f3ba65ceb141033
https://doi.org/10.1016/j.semcdb.2015.10.004
https://doi.org/10.1016/j.semcdb.2015.10.004
Autor:
Karina Polanco, Revathi Balasubramanian, Xin Zhang, Jian Zhong, Chenqi Tao, Fen Wang, Liang Ma
The mammalian ciliary margin is a part of the developing peripheral neural retina that differentiates into the ciliary body and the iris. Canonical WNT signaling plays a critical role in the specification of the ciliary margin at the peripheral retin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d662a2bfddf4cbe48e2d2b6e88da8ca
https://doi.org/10.1101/443416
https://doi.org/10.1101/443416