Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Revandkar A"'
TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state
Autor:
Matsuda, Satoru, Revandkar, Ajinkya, Dubash, Taronish D., Ravi, Arvind, Wittner, Ben S., Lin, Maoxuan, Morris, Robert, Burr, Risa, Guo, Hongshan, Seeger, Karsen, Szabolcs, Annamaria, Che, Dante, Nieman, Linda, Getz, Gad A., Ting, David T., Lawrence, Michael S., Gainor, Justin, Haber, Daniel A., Maheswaran, Shyamala
Publikováno v:
In Cell Reports 28 March 2023 42(3)
TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state
Autor:
Satoru Matsuda, Ajinkya Revandkar, Taronish D. Dubash, Arvind Ravi, Ben S. Wittner, Maoxuan Lin, Robert Morris, Risa Burr, Hongshan Guo, Karsen Seeger, Annamaria Szabolcs, Dante Che, Linda Nieman, Gad A. Getz, David T. Ting, Michael S. Lawrence, Justin Gainor, Daniel A. Haber, Shyamala Maheswaran
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112129- (2023)
Summary: TGF-β induces senescence in embryonic tissues. Whether TGF-β in the hypoxic tumor microenvironment (TME) induces senescence in cancer and how the ensuing senescence-associated secretory phenotype (SASP) remodels the cellular TME to influen
Externí odkaz:
https://doaj.org/article/d7cf1d03230041eaa0fc9ddd6ef3a6cf
Autor:
Martina Troiani, Manuel Colucci, Mariantonietta D’Ambrosio, Ilaria Guccini, Emiliano Pasquini, Angelica Varesi, Aurora Valdata, Simone Mosole, Ajinkya Revandkar, Giuseppe Attanasio, Andrea Rinaldi, Anna Rinaldi, Marco Bolis, Pietro Cippà, Andrea Alimonti
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Abstract Cells subjected to treatment with anti-cancer therapies can evade apoptosis through cellular senescence. Persistent senescent tumor cells remain metabolically active, possess a secretory phenotype, and can promote tumor proliferation and met
Externí odkaz:
https://doaj.org/article/c5129a2c73bf496996067c83544c9029
Autor:
Martina Troiani, Manuel Colucci, Mariantonietta D’Ambrosio, Ilaria Guccini, Emiliano Pasquini, Angelica Varesi, Aurora Valdata, Simone Mosole, Ajinkya Revandkar, Giuseppe Attanasio, Andrea Rinaldi, Anna Rinaldi, Marco Bolis, Pietro Cippà, Andrea Alimonti
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/f6425f31869a4c14b0bd184a4c42baaf
Akademický článek
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Autor:
Ashish Birla, Vaibhav Revandkar, Shivendra Singh, Arvind Conjeevaram, M A Abraham, Siddharth Mavani
Publikováno v:
Journal of Drug Delivery and Therapeutics. 12:181-191
Nifedipine is a classical dihydropyridine calcium channel blocker (CCB) indicated for the management of hypertension, vasospastic angina and chronic stable angina. Prestigious regulatory bodies like USFDA, EMA, CDSCO and TGA have approved long-acting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7933ae01a144627528e20d9449cde83d
https://doi.org/10.22270/jddt.v12i4-s.5483
https://doi.org/10.22270/jddt.v12i4-s.5483
Autor:
Ajinkya Revandkar, Maria Luna Perciato, Alberto Toso, Abdullah Alajati, Jingjing Chen, Hermeto Gerber, Mitko Dimitrov, Andrea Rinaldi, Nicolas Delaleu, Emiliano Pasquini, Rocco D’Antuono, Sandra Pinton, Marco Losa, Letizia Gnetti, Alberto Arribas, Patrick Fraering, Francesco Bertoni, Alain Nepveu, Andrea Alimonti
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Notch signalling is involved in prostate cancer progression and therapeutic resistance. Here, the authors show that loss of PTEN in prostate cancer models results in increased Notch1 cleavage and activation through CUX1-mediated transactivation of AD
Externí odkaz:
https://doaj.org/article/ea3cbc2df78f4176a7c391021d800478
Autor:
Diletta Di Mitri, Michela Mirenda, Jelena Vasilevska, Arianna Calcinotto, Nicolas Delaleu, Ajinkya Revandkar, Veronica Gil, Gunther Boysen, Marco Losa, Simone Mosole, Emiliano Pasquini, Rocco D’Antuono, Michela Masetti, Elena Zagato, Giovanna Chiorino, Paola Ostano, Andrea Rinaldi, Letizia Gnetti, Mariona Graupera, Ana Raquel Martins Figueiredo Fonseca, Ricardo Pereira Mestre, David Waugh, Simon Barry, Johann De Bono, Andrea Alimonti
Publikováno v:
Cell Reports, Vol 28, Iss 8, Pp 2156-2168.e5 (2019)
Summary: Tumor-associated macrophages (TAMs) represent a major component of the tumor microenvironment supporting tumorigenesis. TAMs re-education has been proposed as a strategy to promote tumor inhibition. However, whether this approach may work in
Externí odkaz:
https://doaj.org/article/bd61da240095429da7e0533bf6e52fb0
Autor:
Alberto Toso, Ajinkya Revandkar, Diletta Di Mitri, Ilaria Guccini, Michele Proietti, Manuela Sarti, Sandra Pinton, Jiangwen Zhang, Madhuri Kalathur, Gianluca Civenni, David Jarrossay, Erica Montani, Camilla Marini, Ramon Garcia-Escudero, Eugenio Scanziani, Fabio Grassi, Pier Paolo Pandolfi, Carlo V. Catapano, Andrea Alimonti
Publikováno v:
Cell Reports, Vol 9, Iss 1, Pp 75-89 (2014)
Summary: Prosenescence therapy has recently emerged as a novel therapeutic approach for treating cancer. However, this concept is challenged by conflicting evidence showing that the senescence-associated secretory phenotype (SASP) of senescent tumor
Externí odkaz:
https://doaj.org/article/c94fd7136b0645978c258289d1966502
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.