Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Reuven, Reich"'
Autor:
Sheethal Thomas Mannully, Rawan Mahajna, Huda Nazzal, Salam Maree, Hongchao Zheng, Daniel H. Appella, Reuven Reich, Eylon Yavin
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 609 (2024)
Ovarian cancer (OC) is one of the most lethal gynecologic cancers that is typically diagnosed at the very late stage of disease progression. Thus, there is an unmet need to develop diagnostic probes for early detection of OC. One approach may rely on
Externí odkaz:
https://doaj.org/article/b3b133fc6e13443a9a6fda6c8197c099
Publikováno v:
Journal of Biological Engineering, Vol 14, Iss 1, Pp 1-12 (2020)
Abstract Background Implantation failure remains an unsolved obstacle in reproductive medicine. Previous studies have indicated that estrogen responsiveness, specifically by estrogen receptor alpha (ERα), is crucial for proper implantation. There is
Externí odkaz:
https://doaj.org/article/1c050d19dd7a48d687ead5986a89d8d8
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13286 (2022)
Phospholipase D (PLD) isoenzymes participate in a variety of cellular functions that are mostly attributed to phosphatidic acid (PA) synthesis. Dysregulation of PLD regulates tumor progression and metastasis, yet little is known about the underlying
Externí odkaz:
https://doaj.org/article/f0a2da6782504f21bad8f5c86973752f
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12647 (2021)
The aim of this study was to analyze the biological role of different transforming growth factor-β (TGFβ) receptor splice variants in ovarian carcinoma (OC). Specific receptor variant knockouts (KO) were prepared using the CRISPR/Cas9 genome editin
Externí odkaz:
https://doaj.org/article/5194528a9c1f45b397c48710f820741f
Supplementary Figure 1 from Small Interfering RNA Molecules Targeting Endothelin-Converting Enzyme-1 Inhibit Endothelin-1 Synthesis and the Invasive Phenotype of Ovarian Carcinoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6b401445e8243b1d9c94b52296739a
https://doi.org/10.1158/0008-5472.22375727.v1
https://doi.org/10.1158/0008-5472.22375727.v1
Supplementary Figure Legend from Small Interfering RNA Molecules Targeting Endothelin-Converting Enzyme-1 Inhibit Endothelin-1 Synthesis and the Invasive Phenotype of Ovarian Carcinoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043e693fa7013c6e1e6bc70dba8d1b35
https://doi.org/10.1158/0008-5472.22375724
https://doi.org/10.1158/0008-5472.22375724
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5237 (2020)
The objective of the present study was to analyze the biological and clinical role of the long non-coding RNA LOC642852 in ovarian carcinoma (OC). LOC642852 expression was analyzed in seven OC cell lines (OVCAR-3, OVCAR-8, OVCA 433, OVCA 429, OC 238,
Externí odkaz:
https://doaj.org/article/3eb72774bba140fc8527ddca7f5b6627
Autor:
Avraham Maimon, Maxim Mogilevsky, Asaf Shilo, Regina Golan-Gerstl, Akram Obiedat, Vered Ben-Hur, Ilana Lebenthal-Loinger, Ilan Stein, Reuven Reich, Jonah Beenstock, Eldar Zehorai, Claus L. Andersen, Kasper Thorsen, Torben F. Ørntoft, Roger J. Davis, Ben Davidson, David Mu, Rotem Karni
Publikováno v:
Cell Reports, Vol 7, Iss 2, Pp 501-513 (2014)
Summary: The kinase Mnk2 is a substrate of the MAPK pathway and phosphorylates the translation initiation factor eIF4E. In humans, MKNK2, the gene encoding for Mnk2, is alternatively spliced yielding two splicing isoforms with differing last exons: M
Externí odkaz:
https://doaj.org/article/bf0775f207b84a6085b0d57af787b01d
Publikováno v:
Anticancer Research. 40:6677-6684
Aim To analyze the biological role of the long non-coding RNA LINK-A. Materials and methods An 850-bp segment from the second exon of LINK-A was removed using the CRISPR/Cas9 system in OVCA433 ovarian serous carcinoma cells. Spheroid formation, migra
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162502 (2016)
OBJECTIVE:Ezrin and p130Cas are structural proteins with an important role in signaling pathways and have been shown to promote cancer dissemination. We previously reported on overexpression of both ezrin and p130Cas in breast carcinoma effusions com
Externí odkaz:
https://doaj.org/article/c3c3117aa7fe4eacb0067d86365db2ee