Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Reut Shema"'
Autor:
Yinqing Li, Zhanyan Fu, Holger Lerche, Stephen Sanders, Andreas Brunklaus, Xian Adiconis, Joshua Z. Levin, Dennis Lal, Steven A. McCarroll, Miriam H. Meisler, Boaz Barak, Cynthia C. Hession, Reut Shema, Rikke S. Møller, Sean Simmons, Guoping Feng, Juanjiangmeng Du, Arthur J. Campbell
Publikováno v:
Du, J, Simmons, S, Brunklaus, A, Adiconis, X, Hession, C C, Fu, Z, Li, Y, Shema, R, Møller, R S, Barak, B, Feng, G, Meisler, M, Sanders, S, Lerche, H, Campbell, A J, McCarroll, S, Levin, J Z & Lal, D 2020, ' Differential excitatory vs inhibitory SCN expression at single cell level regulates brain sodium channel function in neurodevelopmental disorders ', European Journal of Paediatric Neurology, vol. 24, pp. 129-133 . https://doi.org/10.1016/j.ejpn.2019.12.019
The four voltage-gated sodium channels SCN1/2/3/8A have been associated with heterogeneous types of developmental disorders, each presenting with disease specific temporal and cell type specific gene expression. Using single-cell RNA sequencing trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1ce5f7bf63dbbf3614811396306c09
https://doi.org/10.1016/j.ejpn.2019.12.019
https://doi.org/10.1016/j.ejpn.2019.12.019
Publikováno v:
Proceedings of the National Academy of Sciences. 112:268-272
Huntington's disease, the most common inherited neurodegenerative disease, is characterized by a dramatic loss of deep-layer cortical and striatal neurons, as well as morbidity in midlife. Human genetic studies led to the identification of the causat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b57d7957d0d6f914fd7b163a4fc1c23
https://doi.org/10.1073/pnas.1417231112
https://doi.org/10.1073/pnas.1417231112
Enhancement of Consolidated Long-Term Memory by Overexpression of Protein Kinase Mζ in the Neocortex
Autor:
Shoshi Hazvi, Sharon Haramati, Reut Shema, Yadin Dudai, Shiri Ron, Todd Charlton Sacktor, Alon Chen
Publikováno v:
Science. 331:1207-1210
Memories are more easily disrupted than improved. Many agents can impair memories during encoding and consolidation. In contrast, the armamentarium of potential memory enhancers is so far rather modest. Moreover, the effect of the latter appears to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6554078bd7ad4f6eac4d1c7a18628cf
https://doi.org/10.1126/science.1200215
https://doi.org/10.1126/science.1200215
Publikováno v:
Science. 317:951-953
Little is known about the neuronal mechanisms that subserve long-term memory persistence in the brain. The components of the remodeled synaptic machinery, and how they sustain the new synaptic or cellwide configuration over time, are yet to be elucid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03c47539e6202368ecc61b316c1cdac
https://doi.org/10.1126/science.1144334
https://doi.org/10.1126/science.1144334
We report here that ZIP, a selective inhibitor of the atypical protein kinase C isoform PKMζ, abolishes very long-term conditioned taste aversion (CTA) associations in the insular cortex of the behaving rat, at least 3 mo after encoding. The effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08fc0cb52da6e32126621191eef15b39
https://europepmc.org/articles/PMC2661244/
https://europepmc.org/articles/PMC2661244/
Autor:
Graham D. Pavitt, Scott L. Diamond, Reut Shema, Danielle Burgess, Nuzhat Motlekar, Andrew D. Napper, Rogerio Alves de Almeida
Publikováno v:
Yeast (Chichester, England). 25(1)
Reporter-gene assays that employ the Escherichia coli lacZ gene are ubiquitously employed in biological research. However, we were not able to readily identify a quantitative method that worked reliably with yeast (Saccharomyces cerevisiae) cells and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b410f6510cf27c1d66f6e3f263fd47d7
https://pubmed.ncbi.nlm.nih.gov/17957822
https://pubmed.ncbi.nlm.nih.gov/17957822
Autor:
Monika S. Kowalczyk, Michael M. Halassa, Mario A. Arias-Garcia, Eunjin Hwang, Alexandra Krol, João Peça, Reut Shema, Soon-Wook Choi, X. M. Sun, Sean Simmons, Joshua Z. Levin, Ralf D. Wimmer, Diya Malhotra, Taibo Li, Dasheng Bi, Kirsten Levandowski, Marcos António Gomes, Yinqing Li, Annie Y. Yao, Cynthia C. Hession, Tomomi Aida, Baolin Guo, Timothy R. Blosser, Zhanyan Fu, Alexander Atamian, Gang Pan, Guoping Feng, Tina Naik, Violeta G. Lopez-Huerta, Xian Adiconis
Publikováno v:
Nature
The thalamic reticular nucleus (TRN), the major source of thalamic inhibition, regulates thalamocortical interactions that are critical for sensory processing, attention and cognition1–5. TRN dysfunction has been linked to sensory abnormality, atte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5d61822d4dcb88c9030a7fa8d40728