Longitudinal Evaluation of Individuals With Severe Alpha-1 Antitrypsin Deficiency (Pi∗ZZ Genotype).

Autor: Fromme M; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Payancé A; AP-HP, Service d'hépatologie, Hôpital Beaujon, AP-HP, Clichy, France, DMU Digest, Centre de référence des Maladies Vasculaires du foie, FILFOIE, Clichy, France, Université Paris Cité, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Paris, France., Mandorfer M; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Vienna, Austria., Thorhauge KH; Department of Gastroenterology and Hepatology, Odense University Hospital, Odense C, Denmark; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense C, Denmark., Pons M; Liver Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institute of Research (VHIR), Vall d'Hebron Barcelona Hospital Campus, Universitat Autonoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain., Miravitlles M; Pneumology Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, CIBER de Enfermedades Respiratorias (CIBERES), Health Care Provider of the European Reference Network on Rare Respiratory Diseases (ERN LUNG), Barcelona, Spain., Stolk J; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., van Hoek B; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands., Stirnimann G; University Clinic for Visceral Surgery and Medicine, University Hospital Inselspital and University of Bern, Bern, Switzerland., Frankova S; Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Prague, Czech Republic., Sperl J; Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Prague, Czech Republic., Kremer AE; Department of Gastroenterology and Hepatology, University Hospital Zürich, University of Zürich, Zürich, Switzerland., Burbaum B; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Schrader C; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Kadioglu A; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Walkenhaus M; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Schneider CV; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Klebingat F; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Balcar L; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Vienna, Austria., Kappe NN; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands., Schaefer B; Department of Internal Medicine I, Medical University Innsbruck, Innsbruck, Austria., Chorostowska-Wynimko J; Department of Genetics and Clinical Immunology, National Institute of Tuberculosis and Lung Diseases, Warsaw, Poland., Aigner E; First Department of Medicine, Paracelsus Medical University Salzburg, Salzburg, Austria., Gensluckner S; First Department of Medicine, Paracelsus Medical University Salzburg, Salzburg, Austria., Striedl P; First Department of Medicine, Paracelsus Medical University Salzburg, Salzburg, Austria., Roger P; AP-HP, service d'hépatologie, Hôpital Beaujon, AP-HP, Clichy, France, DMU Digest, Clichy, France., Ryan J; Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland., Roche S; Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland., Vögelin M; Department of Gastroenterology and Hepatology, University Hospital Zürich, University of Zürich, Zürich, Switzerland., Ala A; Institute of Liver Studies, King's College Hospital NHS Foundation Trust, London, United Kingdom., Bantel H; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany., Verbeek J; Department of Gastroenterology & Hepatology, KU Leuven University Hospitals, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Leuven, Belgium., Mariño Z; Liver Unit, Hospital Clínic Barcelona, Instituto de Investigaciones Biomédicas August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), University of Barcelona, Barcelona, Spain., Praktiknjo M; Department of Medicine B, Gastroenterology, Hepatology, Endocrinology, Infectious Diseases, Universitätsklinikum Muenster, Muenster, Germany., Gevers TJG; Department of Gastroenterology and Hepatology, Maastricht University Medical Centre, Maastricht, The Netherlands., Reuken PA; Department of Internal Medicine IV, Jena University Hospital, Friedrich Schiller University, Jena, Germany., Berg T; Division of Hepatology, Department of Medicine, Leipzig University Medical Center, Leipzig, Germany., George J; Storr Liver Centre, The Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Sydney, New South Wales, Australia., Demir M; Department of Hepatology and Gastroenterology, Campus Virchow-Klinikum and Campus Charité Mitte, Charité Universitätsmedizin Berlin, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Berlin, Germany., Bruns T; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Trautwein C; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany; Department of Toxicology, Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany., Zoller H; Department of Internal Medicine I, Medical University Innsbruck, Innsbruck, Austria., Trauner M; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Vienna, Austria., Genesca J; Liver Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institute of Research (VHIR), Vall d'Hebron Barcelona Hospital Campus, Universitat Autonoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain., Griffiths WJ; Department of Hepatology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom., Clark V; Division of Gastroenterology, Hepatology, and Nutrition, University of Florida, Gainesville, Florida., Krag A; Department of Gastroenterology and Hepatology, Odense University Hospital, Odense C, Denmark; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense C, Denmark., Turner AM; Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom., McElvaney NG; Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland., Strnad P; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany. Electronic address: pstrnad@ukaachen.de.

Publikováno v: Gastroenterology [Gastroenterology] 2025 Feb; Vol. 168 (2), pp. 367-381. Date of Electronic Publication: 2024 Oct 15.

Type-I interferon shapes peritoneal immunity in cirrhosis and drives caspase-5-mediated progranulin release upon infection.

Autor: Rooney M; Department of Internal Medicine IV, Jena University Hospital, Friedrich Schiller University, Jena, Germany; Integrated Research and Treatment Center, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany., Duduskar SN; Integrated Research and Treatment Center, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany., Ghait M; Integrated Research and Treatment Center, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany., Reißing J; Department of Internal Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Stengel S; Department of Internal Medicine IV, Jena University Hospital, Friedrich Schiller University, Jena, Germany; Department of Neuropediatrics, Jena University Hospital, 07747 Jena, Germany., Reuken PA; Department of Internal Medicine IV, Jena University Hospital, Friedrich Schiller University, Jena, Germany., Quickert S; Department of Internal Medicine IV, Jena University Hospital, Friedrich Schiller University, Jena, Germany., Zipprich A; Department of Internal Medicine IV, Jena University Hospital, Friedrich Schiller University, Jena, Germany., Bauer M; Integrated Research and Treatment Center, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich Schiller University, Jena, Germany., Russo AJ; Department of Immunology, University of Connecticut Health School of Medicine, 263 Farmington Avenue, Farmington, CT 06030, USA., Rathinam VA; Department of Immunology, University of Connecticut Health School of Medicine, 263 Farmington Avenue, Farmington, CT 06030, USA., Stallmach A; Department of Internal Medicine IV, Jena University Hospital, Friedrich Schiller University, Jena, Germany., Rubio I; Integrated Research and Treatment Center, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich Schiller University, Jena, Germany., Bruns T; Department of Internal Medicine III, University Hospital RWTH Aachen, Aachen, Germany. Electronic address: tbruns@ukaachen.de.

Publikováno v: Journal of hepatology [J Hepatol] 2024 Dec; Vol. 81 (6), pp. 971-982. Date of Electronic Publication: 2024 Jun 25.

Comparative effectiveness of vancomycin and metronidazole on event-free survival after initial infection in patients with Clostridioides difficile-a German multicentre cohort study.

Autor: Conrad J; Institute of Medical Biometry, Epidemiology and Informatics, University Medicine of the Johannes Gutenberg University of Mainz, Mainz, Germany., Giesbrecht K; Department of Internal Medicine, Infectious Diseases, Goethe University Frankfurt, University Hospital Frankfurt, Frankfurt/Main, Germany., Aguilar RC; Department I of Internal Medicine, Division of Infectious Diseases, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany., Gräfe SK; Department I of Internal Medicine, Faculty of Medicine, ECMM Excellence Centre for Medical Mycology, University Hospital of Cologne, Cologne, Germany., Ullah A; Department I of Internal Medicine, Division of Infectious Diseases, Medical Faculty and University Hospital Cologne, Cologne, Germany; Department I of Internal Medicine, Division of Kardiology und Internistic Intensive Care, Klinikum Leverkusen, Leverkusen, Germany., Hunfeld KP; Institute for Laboratory Medicine, Microbiology and Infection Control, Northwest Medical Centre, Frankfurt/Main, Germany., Lübbert C; Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, University of Leipzig Medical Centre, Leipzig, Germany., Pützfeld S; Division of Gastroenterology and Internal Medicine, Hospital Porz am Rhein, Cologne, Germany., Reuken PA; Department of Internal Medicine IV, Jena University Hospital, Jena, Germany., Schmitz-Rode M; Department of Geriatrics, Evangelisches Krankenhaus Kalk, Cologne, Germany., Schalk E; Department of Hematology, Oncology and Cell Therapy, Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany., Schmidt-Wilcke T; Centre of Neurology, District Hospital Mainkofen, Deggendorf, Germany; St Mauritius Therapieklinik, Meerbusch, Germany., Schmiedel S; I. Department of Internal Medicine, Section Infectious Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Solbach P; Department of Medicine I, University Hospital Schleswig-Holstein, Lübeck, Germany., Vehreschild MJGT; Department of Internal Medicine, Infectious Diseases, Goethe University Frankfurt, University Hospital Frankfurt, Frankfurt/Main, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt am Main, Germany. Electronic address: vehreschild@med.uni-frankfurt.de.

Publikováno v: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2024 Nov; Vol. 30 (11), pp. 1433-1438. Date of Electronic Publication: 2024 Aug 08.

Web-based telemedicine approach for treatment of post-COVID-19 in Thuringia (WATCH).

Autor: Reuken PA; Department for Internal Medicine IV (Gastroenterology, Hepatology and Infectious Diseases), Jena University Hospital, Jena, Germany.; Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany., Besteher B; Department of Psychiatry, Jena University Hospital, Jena, Germany., Bleidorn J; Institute of General Practice, University Hospital Jena, Jena, Germany., Brockmann D; Center Synergy of Systems (SynoSys), Faculty of Biology, Technical University of Dresden, Dresden, Germany., Finke K; Department of Neurology, Jena University Hospital, Jena, Germany., Freytag A; Institute of General Practice, University Hospital Jena, Jena, Germany., Lehmann-Pohl K; Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany., Lemhöfer C; Institute of Physical and Rehabilitation Medicine, Jena University Hospital, Jena, Germany., Mikolajczyk R; Institute for Medical Epidemiology, Biometrics, and Informatics, Medical Faculty of the Martin Luther University Halle-Wittenberg, Halle (Saale), Deutschland., Puta C; Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany.; Department of Sports Medicine and Health Promotion, Friedrich-Schiller-University Jena, Jena, Germany., Scherag A; Institute of Medical Statistics, Computer and Data Sciences, Jena University Hospital, Jena, Germany., Wiedermann M; Computational Epidemiology Group, Robert Koch Institute, Berlin, Germany., Zippel-Schultz B; German Foundation for the Chronically Ill, Berlin, Germany., Stallmach A; Department for Internal Medicine IV (Gastroenterology, Hepatology and Infectious Diseases), Jena University Hospital, Jena, Germany.; Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany.

Publikováno v: Digital health [Digit Health] 2024 Oct 14; Vol. 10, pp. 20552076241291748. Date of Electronic Publication: 2024 Oct 14 (Print Publication: 2024).

Autor: Posovszky C; Gastroenterologie und Ernährung, Universitäts-Kinderspital Zürich, Zurich, Switzerland.; Klinik für Kinder- und Jugendmedizin, University Ulm Medical Centre, Ulm, Germany., Buderus S; GFO Kliniken Bonn Betriebsstätte St Marien, Bonn, Germany., Huebner J; Dr. von Haunersches Kinderspital, Abteilung Pädiatrische Infektiologie, Klinikum der Ludwig-Maximilians-Universität München, Munchen, Germany., Adam R; Ped. Gastroenterology, Universitätsklinikum Mannheim Klinik für Kinder- und Jugendmedizin, Mannheim, Germany., Papan C; Institut für Hygiene und Public Health, Universitätsklinikum Bonn, Germany., Gruber B; Marienhospital Osnabrück, Niels-Stensen-Kliniken GmbH, Georgsmarienhutte, Germany., Schmid F; Kindergastroenterologie, Katholisches Kinderkrankenhaus Wilhelmstift gGmbH, Hamburg, Germany., Krohn K; Integriertes Sozialpädiatrisches Zentrum im Dr. von Haunerschen Kinderspital, Ludwig-Maximilians-Universität München, Munchen, Germany., Wintermeyer P; School of Medicine and Health, Departement of Clinical Medicine, Technische Universität München, Munchen, Germany., Schwenke R; Akademische Lehr- und Forschungspraxis der Universität Heidelberg, Gemeinschaftspraxis für Allgemein- und Familienmedizin, Walzbachtal, Germany., Laffolie J; Paediatrics, Justus Liebig Universitat Giessen Fachbereich Medizin, Giessen, Germany., Both U; Dr. von Haunersches Kinderspital, Abteilung Pädiatrische Infektiologie, Ludwig-Maximilians-Universität München, Munchen, Germany., Epple HJ; Gastroenterology, Charité-Campus Benjamin Franklin, Berlin, Germany., Reuken PA; Klinik für Innere Medizin IV, Universitatsklinikum Jena, Germany., Kipfmüller F; Neonatologie & Pädiatrische Intensivmedizin, Universitätsklinikum Bonn, Germany., Schneider AM; Universitätsklinik für Kinder- und Jugendheilkunde der PMU, Pädiatrische Gastroenterologie, Hepatologie und Ernährung, Uniklinikum Salzburg, Germany., Fruth A; Fachgebiet 11 'Bakterielle darmpathogene Erreger und Legionellen', NRZ Salmonellen und andere bakterielle Enteritiserreger, Robert Koch-Institut, Berlin, Germany., Simon S; Fachgebiet 11 'Bakterielle darmpathogene Erreger und Legionellen', Robert Koch-Institut, Berlin, Germany., Schmitt A; University of Applied Sciences, Fachbereich Gesundheit und Pflege, Ernst-Abbe-Hochschule Jena, Germany., Hauer AC; Univ.-Klinik für Kinder- und Jugendheilkunde, Medizinische Universität Graz, Austria.

Publikováno v: Zeitschrift fur Gastroenterologie [Z Gastroenterol] 2024 Sep; Vol. 62 (9), pp. 1574-1643. Date of Electronic Publication: 2024 Sep 09.