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Potency by design: Novel insights in transfection and purification for manufacturing of rAAV gene therapy vectors.

Autor: Maccani A; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria., Pachlinger R; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria., Eisenhut P; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria., Unterthurner S; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria., Heider S; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria., Repik C; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria., Reuberger S; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria., Andorfer P; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria., Lengler J; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria., Kinastberger B; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria., Seczer D; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria., Gruber P; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria., Apschner A; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria. Electronic address: alexander.apschner@takeda.com., Micutkova L; Gene Therapy Process Development, Baxalta Innovations GmbH, part of Takeda companies, Orth an der Donau, 2304 Orth an der Donau, Austria. Electronic address: lucia.micutkova@yahoo.com.

Publikováno v: Journal of biotechnology [J Biotechnol] 2024 Dec 17; Vol. 398, pp. 127-132. Date of Electronic Publication: 2024 Dec 17.