Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Reuben Shaw"'
Autor:
Annie Lee, Chandana Kondapalli, Daniel M. Virga, Tommy L. Lewis, So Yeon Koo, Archana Ashok, Georges Mairet-Coello, Sebastien Herzig, Marc Foretz, Benoit Viollet, Reuben Shaw, Andrew Sproul, Franck Polleux
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Loss of excitatory synapses occur prior to the formation of amyloid plaques in Alzheimer’s disease. Here the authors show in an animal model that the loss of synapses induced by amyloid-beta oligomers requires over-activation of a stress-response p
Externí odkaz:
https://doaj.org/article/e4cca8864343441c862cd2169b11e9ee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
It is unclear how and why axonal mitochondria are kept so small in axons. Authors show here that MFF-mediated fission is required for determining the size of mitochondria both entering and along the axon, and this is critical for mitochondrial calciu
Externí odkaz:
https://doaj.org/article/6011499af941422d9a5a9a83b3117271
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31900 (2012)
Tuberous sclerosis complex (TSC) is a human genetic disorder in which loss of either TSC1 or TSC2 leads to development of hamartoma lesions, which can progress and be life-threatening or fatal. The TSC1/TSC2 protein complex regulates the state of act
Externí odkaz:
https://doaj.org/article/72671e4b03ab4e57a629607d5c8c08e6
Autor:
Caryn Lerman, Chanita Hughes-Halbert, Mary Falcone, David M Gosky, Roy A Jensen, Kelvin P Lee, Edith Mitchell, Kunle Odunsi, Jennifer W Pegher, Elisa Rodriguez, Yolanda Sanchez, Reuben Shaw, George Weiner, Cheryl L Willman
Publikováno v:
JNCI: Journal of the National Cancer Institute. 114:1214-1221
The capacity and diversity of the oncology leadership workforce has not kept pace with the emerging needs of our increasingly complex cancer centers and the spectrum of challenges our institutions face in reducing the cancer burden in diverse catchme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb240a798e5205b4cf6a2ea196b811b9
https://doi.org/10.1093/jnci/djac121
https://doi.org/10.1093/jnci/djac121
Autor:
Alexandra Kuhlmann-Hogan, Thekla Cordes, Ziyan Xu, Kacie A. Traina, Camila Robles-Oteíza, Deborah Ayeni, Elizabeth M. Kwong, Stellar R. Levy, Mathew Nobari, George Z. Cheng, Reuben Shaw, Sandra L. Leibel, Christian M. Metallo, Katerina Politi, Susan M. Kaech
Publikováno v:
bioRxiv
The limited efficacy of currently approved immunotherapies in EGFR-mutant lung adenocarcinoma (LUAD) underscores the need to better understand mechanisms governing local immunosuppression. Elevated surfactant and GM-CSF secretion from the transformed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06821c4e35a9bc53d4335381263abcc3
https://doi.org/10.1101/2023.04.15.536974
https://doi.org/10.1101/2023.04.15.536974
Autor:
Annie Lee, Chandana Kondapalli, Daniel M. Virga, Tommy L. Lewis, So Yeon Koo, Archana Ashok, Georges Mairet-Coello, Sebastien Herzig, Marc Foretz, Benoit Viollet, Reuben Shaw, Andrew Sproul, Franck Polleux
Publikováno v:
Nature Communications
Nature Communications, 2022, 13 (1), pp.4444. ⟨10.1038/s41467-022-32130-5⟩
Nature Communications, 2022, 13 (1), pp.4444. ⟨10.1038/s41467-022-32130-5⟩
During the early stages of Alzheimer’s disease (AD) in both mouse models and human patients, soluble forms of Amyloid-β 1–42 oligomers (Aβ42o) trigger loss of excitatory synapses (synaptotoxicity) in cortical and hippocampal pyramidal neurons (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460af2ea012485e058110bf60eec2fce
https://pubmed.ncbi.nlm.nih.gov/35915085
https://pubmed.ncbi.nlm.nih.gov/35915085
Autor:
Reuben Shaw
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47acc11e589f83275fb9694d7d90ea68
https://doi.org/10.1096/fasebj.26.1_supplement.231.3
https://doi.org/10.1096/fasebj.26.1_supplement.231.3
Autor:
Reuben, Shaw
Publikováno v:
Nature. 462(7275)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::347cf5dd76e6926464d636b5de8fc918
https://pubmed.ncbi.nlm.nih.gov/20016556
https://pubmed.ncbi.nlm.nih.gov/20016556