Multidimensional reduction of multicentric cohort heterogeneity: An alternative method to increase statistical power and robustness

Autor: Le Gall, Caroline, Laurent, Julie, Vince, Nicolas, Lizee, Antoine, Agrawal, Alisha, Walencik, Alexandre, Rettman, Pauline, Gagne, Katia, Retiere, Christelle, Hollenbach, Jill, Cesbron, Anne, Limou, Sophie, Gourraud, Pierre-Antoine

Publikováno v: In Human Immunology November 2016 77(11):1024-1029

A novel antibody combination to identify KIR2DS2^high natural killer cells in KIR2DL3/L2/S2 heterozygous donors.

Autor: Blunt, Matthew D.¹, Rettman, Pauline¹, Bastidas‐Legarda, Leidy Y.¹, Fulton, Rebecca¹, Capizzuto, Valentina¹, Naiyer, Mohammed M.¹, Khakoo, Salim I.¹, Traherne, James A.²

Publikováno v: HLA: Immune Response Genetics. Jan2019, Vol. 93 Issue 1, p32-35. 4p. 2 Graphs.

A DNA vaccine strategy to activate natural killer cells for therapeutic targeting of XPO1-positive tumors

Autor: Rettman, Pauline, Blunt, Matthew D., Mbiribindi, Berenice, Fulton, Rebecca, Schittenhelm, Ralf B., Pulido, Andres Vallejo, Bastidas-Legarda, Leidy, Polak, Marta E., Ayala, Rochelle, Purcell, Anthony W., Al-Shamkhani, Aymen, Retiere, Christelle, Khakoo, Salim I.

Natural killer (NK) cells are increasingly being recognized as agents for cancer immunotherapy. KIR2DS2 is an activating killer-cell immunoglobulin-like receptor (KIR) expressed by NK cells, which has been associated with protective responses to canc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=sharebioRxiv::d1a76e6d1a06f51170719961fbb93f93

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KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C

Autor: Naiyer, Mohammed M., Cassidy, Sorcha A., Magri, Andrea, Cowton, Vanessa, Chen, Kevin, Mansour, Salah, Kranidioti, Hariklia, Mbirbindi, Berenice, Rettman, Pauline, Harris, Scott, Fanning, Liam J., Mulder, Arend, Claas, Franz H.J., Davidson, Andrew D., Patel, Arvind H., Purbhoo, Marco A., Khakoo, Salim I.

Publikováno v: Naiyer, M M, Cassidy, S A, Magri, A, Cowton, V, Chen, K, Mansour, S, Kranidioti, H, Mbirbindi, B, Rettman, P, Harris, S, Fanning, L J, Mulder, A, Claas, F H J, Davidson, A D, Patel, A H, Purbhoo, M A & Khakoo, S I 2017, ' KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C ', Science Immunology, vol. 2, no. 15, eaal5296 . https://doi.org/10.1126/sciimmunol.aal5296

Killer cell immunoglobulin-like receptors (KIRs) are rapidly evolving species-specific natural killer (NK) cell receptors associated with protection against multiple different human viral infections. We report that the activating receptor KIR2DS2 dir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0ea325e3136b29582e863ead5a43d058
https://eprints.soton.ac.uk/414342/