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Publikováno v:
Ibrain, Vol 7, Iss 4, Pp 318-324 (2021)
Abstract Parkinson's disease (PD) is a neurodegenerative disease that is common in middle‐aged and elderly people, and its onset is related to multiple factors, such as heredity, environment, and age. The vesicle protein sorting 35 (VPS35) gene was
Externí odkaz:
https://doaj.org/article/80ac89df0d7f4d2a83398c5ff301927d
Publikováno v:
Journal of Inflammation Research, Vol Volume 14, Pp 7455-7465 (2021)
Alessia Filippone, Tiffany Smith, Domenico Pratico Alzheimer’s Center at Temple, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USACorrespondence: Domenico PraticoAlzheimer’s Center at Temple, Lewis Katz School of Medi
Externí odkaz:
https://doaj.org/article/cc208e23a23d4e52b6a1bff4a5b2ea2a
Publikováno v:
Neurobiology of Disease, Vol 170, Iss , Pp 105768- (2022)
Perturbations of the endolysosomal pathway have been suggested to play an important role in the pathogenesis of several neurodegenerative diseases, including Parkinson's disease (PD) and Alzheimer's disease (AD). Specifically, VPS35 and the retromer
Externí odkaz:
https://doaj.org/article/7d94be93fe884227afd454d03fd354b7
Publikováno v:
Genes and Diseases, Vol 8, Iss 2, Pp 232-240 (2021)
Vesicle Protein Sorting 35 (VPS35) is a novel oncogene that promotes tumor growth through the PI3K/AKT signaling in hepatocellular carcinoma (HCC). However, the role of VPS35 in HCC metastasis and the underlying mechanisms remain largely unclear. In
Externí odkaz:
https://doaj.org/article/b4809dca3f8247d1984d72def20894f7
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-11 (2020)
Abstract Background The vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex system, an ubiquitous multiprotein assembly responsible for sorting and trafficking protein cargos out of the endosomes. VPS35 can regulate APP m
Externí odkaz:
https://doaj.org/article/3bd2ff0d998342d19730ea8e87c87f91
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Aberrations in membrane trafficking pathways have profound effects in cellular dynamics of cellular sorting processes and can drive severe physiological outcomes. Sorting nexin 27 (SNX27) is a metazoan-specific sorting nexin protein from the PX-FERM
Externí odkaz:
https://doaj.org/article/e865b781013641a38967ee4d4c59eb5b
Autor:
Simona Eleuteri, Alberto Albanese
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Several symptomatic treatments for Parkinson's disease (PD) are currently available. Still, the challenge today is to find a therapy that might reduce degeneration and slow down disease progression. The identification of pathogenic mutations in famil
Externí odkaz:
https://doaj.org/article/24eb6419fb3746e9b68187bd2555022f
Autor:
Xuejiao Jin, Huihui Zhao, Min Zhou, Jie Zhang, Tingting An, Wenhao Fu, Danqi Li, Xiuling Cao, Beidong Liu
Publikováno v:
Cells, Vol 10, Iss 12, p 3512 (2021)
Sodium metabisulfite (Na2S2O5) is widely used as a preservative in the food and wine industry. However, it causes varying degrees of cellular damage to organisms. In order to improve our knowledge regarding its cyto-toxicity, a genome-wide screen usi
Externí odkaz:
https://doaj.org/article/13da9e26ef5547adb9e0ab60e63d7592
Publikováno v:
Journal of Inflammation Research, Vol Volume 14, Pp 7455-7465 (2021)
Journal of Inflammation Research
Journal of Inflammation Research
Alessia Filippone, Tiffany Smith, Domenico Pratico Alzheimerâs Center at Temple, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USACorrespondence: Domenico PraticoAlzheimerâs Center at Temple, Lewis Katz School o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6818ebed785b8cd04d78c44cb93b6a41
https://doi.org/10.2147/jir.s342096
https://doi.org/10.2147/jir.s342096