Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Retro-Aldolases"'
Autor:
Hunt, Serena
The creation of artificial enzymes to catalyze desired reactions is a major goal of computational protein design. However, de novo enzymes display low catalytic efficiencies, requiring the introduction of activity-enhancing active site and distal mut
Externí odkaz:
http://hdl.handle.net/10393/45754
Autor:
De Raffele, Daria
Publikováno v:
TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
Fundación Tecnalia Research & Innovation
TDR. Tesis Doctorales en Red
Fundación Tecnalia Research & Innovation
Compendi d'articles, Doctorat internacional The main objective of this dissertation was to investigate the structure-function relationship in different designed Retro-Aldolases, to understand not only their catalytic efficiency but to provide informa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7a28ad4710dd4dc6e85aeb7bf9b45e38
Akademický článek
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Publikováno v:
ACS Catalysis
Enzymes exist as ensembles of conformations that are important for function. Tuning these populations of conformational states through mutation enables evolution toward additional activities. Here we computationally evaluate the population shifts ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5074b938e764ed629e7e39bb41ff7161
