Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Reto M. Witzig"'
Autor:
Daniel Moser, Alessandro Castrogiovanni, Dominik Lotter, Reto M. Witzig, Vincent C. Fäseke, Felix C. Raps, Christof Sparr
Publikováno v:
CHIMIA, Vol 74, Iss 9, Pp 699-703 (2020)
Aldol reactions belong to the most important methods for carbon–carbon bond formation and are also involved in one of the most astonishing biosynthetic processes: the biosynthesis of polyketides governed by an extraordinarily sophisticated enzymati
Externí odkaz:
https://doaj.org/article/88f8f1d28f8f498a939675190ff03f3a
Publikováno v:
CHIMIA, Vol 71, Iss 9 (2017)
By taking inspiration from the fascinating biosynthetic machinery that creates aromatic polyketides, our group investigates analogous reactions catalyzed by small molecules. We are particularly captivated by the prospects of intramolecular aldol cond
Externí odkaz:
https://doaj.org/article/b064aabe52114a04b86cf6788fc61689
Autor:
Christof Sparr, Daniel Häussinger, Christian Fischer, Rodolphe Beaud, Reto M. Witzig, Xingxing Wu
Governing higher-order stereogenicity is a long-standing goal in stereoselective catalysis, because it allows to achieve selectivity for more than a twofold number of stereoisomers per stereogenic unit. Current methods warrant control over the power
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63df52f72371483b8fa1c7df59b25358
https://doi.org/10.26434/chemrxiv.12213362.v1
https://doi.org/10.26434/chemrxiv.12213362.v1
Autor:
Reto M. Witzig, Christof Sparr
The arene-forming aldol condensation is a fundamental reaction in the biosynthesis of aromatic polyketides. Precisely controlled by the polyketide synthases, the highly reactive poly-β-carbonyl substrates are diverged into numerous aromatic natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ced43cf59418469e93d89615a2562e
https://edoc.unibas.ch/74209/
https://edoc.unibas.ch/74209/
Autor:
Christof Sparr, Reto M. Witzig, Daniel Häussinger, Rodolphe Beaud, Christian Fischer, Xingxing Wu
Publikováno v:
Nature Catalysis. 4:534-534
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bf498e0d02c3f253ca4e236f393307a
https://doi.org/10.1038/s41929-021-00645-7
https://doi.org/10.1038/s41929-021-00645-7
The cyclization of poly-β-carbonyl-substrates controlled by polyketide synthases intricately governs the biosynthesis of a wide range of aromatic polyketides. Analogous small-molecule-catalysed processes would conceivably induce selective cyclizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8c9d6b29ae341160ecb19192894d36
https://edoc.unibas.ch/74207/
https://edoc.unibas.ch/74207/
Publikováno v:
Chemistry - A European Journal. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2e45cd35291883f5ae010dd9c25dba3
https://doi.org/10.1002/chem.201785361
https://doi.org/10.1002/chem.201785361
The fundamental role that aldol chemistry adopts in various disciplines, such as stereoselective catalysis or the biosynthesis of aromatic polyketides, illustrates its exceptional versatility. On the one hand, numerous aldol addition reactions reliab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68ad4ae9417ab8e1b81dc4fc4fff0f2
https://edoc.unibas.ch/58699/
https://edoc.unibas.ch/58699/