Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Reto Gassmann"'
Autor:
Francisco Gonçalves-Santos, Ana R.G. De-Castro, Diogo R.M. Rodrigues, Maria J.G. De-Castro, Reto Gassmann, Carla M.C. Abreu, Tiago J. Dantas
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113337- (2023)
Summary: Intraflagellar transport (IFT) trains, built around IFT-A and IFT-B complexes, are carried by opposing motors to import and export ciliary cargo. While transported by kinesin-2 on anterograde IFT trains, the dynein-2 motor adopts an autoinhi
Externí odkaz:
https://doaj.org/article/0a4133805d994faea4b16bdd3f7000a1
Autor:
Joana Leite, Fung-Yi Chan, Daniel S. Osório, Joana Saramago, Ana F. Sobral, Ana M. Silva, Reto Gassmann, Ana X. Carvalho
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Cytokinesis is the last step of cell division that physically partitions the mother cell into two daughter cells. Cytokinesis requires the assembly and constriction of a contractile ring, a circumferential array of filamentous actin (F-actin), non-mu
Externí odkaz:
https://doaj.org/article/5042469f2d964ef8bcb9a5e26d1852fc
Autor:
Ricardo Celestino, Morkos A Henen, José B Gama, Cátia Carvalho, Maxwell McCabe, Daniel J Barbosa, Alexandra Born, Parker J Nichols, Ana X Carvalho, Reto Gassmann, Beat Vögeli
Publikováno v:
PLoS Biology, Vol 17, Iss 1, p e3000100 (2019)
All animal cells use the motor cytoplasmic dynein 1 (dynein) to transport diverse cargo toward microtubule minus ends and to organize and position microtubule arrays such as the mitotic spindle. Cargo-specific adaptors engage with dynein to recruit a
Externí odkaz:
https://doaj.org/article/1692fc10ac154afba4ba231eaae5b7bb
Autor:
Daniel J Barbosa, Joana Duro, Bram Prevo, Dhanya K Cheerambathur, Ana X Carvalho, Reto Gassmann
Publikováno v:
PLoS Genetics, Vol 13, Iss 7, p e1006941 (2017)
The microtubule-based motor dynein generates pulling forces for centrosome centration and mitotic spindle positioning in animal cells. How the essential dynein activator dynactin regulates these functions of the motor is incompletely understood. Here
Externí odkaz:
https://doaj.org/article/b6cfd4153cae4f1ab432df581cdad9a9
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22969 (2011)
Chromosome segregation requires coordinated separation of sister chromatids following biorientation of all chromosomes on the mitotic spindle. Chromatid separation at the metaphase-to-anaphase transition is accomplished by cleavage of the cohesin com
Externí odkaz:
https://doaj.org/article/65c384a3147a4ccb9578befe8aa6b64c
Autor:
Francisco Gonçalves-Santos, Ana R. G. De-Castro, Diogo R. M. Rodrigues, Maria J. G. De-Castro, Reto Gassmann, Carla M. C. Abreu, Tiago J. Dantas
SUMMARYIntraflagellar transport (IFT) trains, built around IFT-A and IFT-B complexes, are carried by opposing motors to import and export ciliary cargo. While transported by kinesin-2 on anterograde IFT trains, the dynein-2 motor adopts an autoinhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6673b11bcc056f6712aafd8273f9e92b
https://doi.org/10.1101/2023.05.10.539247
https://doi.org/10.1101/2023.05.10.539247
Autor:
Reto Gassmann
Publikováno v:
Journal of Cell Science. 136
The microtubule minus-end-directed motility of cytoplasmic dynein 1 (dynein), arguably the most complex and versatile cytoskeletal motor, is harnessed for diverse functions, such as long-range organelle transport in neuronal axons and spindle assembl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b58fc56333119578bd47107708d799b
https://doi.org/10.1242/jcs.220269
https://doi.org/10.1242/jcs.220269
Autor:
Helder Rocha, Patrícia A. Simões, Jacqueline Budrewicz, Pablo Lara-Gonzalez, Ana Xavier Carvalho, Julien Dumont, Arshad Desai, Reto Gassmann
Publikováno v:
Journal of Cell Biology. 222
A landmark event in the transition from interphase to mitosis in metazoans is nuclear envelope breakdown (NEBD). Many events important for mitosis occur prior to NEBD, including condensation of replicated chromosomes and assembly of kinetochores to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a56de3597c7b9fee68e2bb1017d7e87
https://doi.org/10.1083/jcb.202208154
https://doi.org/10.1083/jcb.202208154
Transport of organelles is critical for maintaining healthy neurons. A key adaptor for moving lysosomes in axons is JIP3, which binds both kinesin and dynein motors. Unlike many known dynein adaptors JIP3 contains only a short coiled coil, raising th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a496d0c0c455f8bba9d195f81acd3754
https://doi.org/10.1101/2022.08.17.504273
https://doi.org/10.1101/2022.08.17.504273
Autor:
Diogo R. M. Rodrigues, Ana Carvalho, Neide Vieira, Tiago J. Dantas, Cármen Vieira, Reto Gassmann, Maria J. G. De-Castro, Carla M. Abreu, Ana R. G. De-Castro
Publikováno v:
Journal of Cell Biology. 221
The dynein-2 motor complex drives retrograde intraflagellar transport (IFT), playing a pivotal role in the assembly and functions of cilia. However, the mechanisms that regulate dynein-2 motility remain poorly understood. Here, we identify the Caenor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561ec697d63dff781dde7f46e65bdfc1
https://doi.org/10.1083/jcb.202010178
https://doi.org/10.1083/jcb.202010178