Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Reto Bader"'
Using Structural Information of Peptides, Derived from NMR Spectroscopy, in Pharmaceutical Chemistry
Publikováno v:
CHIMIA, Vol 54, Iss 11 (2000)
The significance of information gained from the solution structure of peptides for pharmaceutical research is demonstrated with two examples: the neuropeptide Y (NPY) hormone system and a undecapeptide designed for use as a chemical sensor. In the ca
Externí odkaz:
https://doaj.org/article/6993ddb4bb544274bdac90fc0f11378f
Autor:
Helen Hoffmeister, Frank Schumann, Ralph Witzgall, M Schmidt, Reto Bader, Hans Robert Kalbitzer
Publikováno v:
Journal of Biological Chemistry. 284:24372-24383
The PKD1 and PKD2 genes are the genes that are mutated in patients suffering from autosomal dominant polycystic kidney disease. The human PKD2 gene codes for a 968-amino acid long membrane protein called polycystin-2 that represents a cation channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db6e0d1ba398827ceaad9992eadb41a
https://doi.org/10.1074/jbc.m109.025635
https://doi.org/10.1074/jbc.m109.025635
Autor:
Reto Bader
Publikováno v:
The Journal of Physical Chemistry B. 113:347-358
Of all the nuclei in proteins, the nuclear magnetic resonance (NMR) chemical shifts of nitrogen are the theoretically least well understood. In this study, quantum chemical methods are used in combination with polarizable-continuum models in order to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae617a83eff0e37b93abde98232dc1e
https://doi.org/10.1021/jp807362v
https://doi.org/10.1021/jp807362v
Publikováno v:
Journal of the American Chemical Society. 129:8811-8817
The minimal model system to study the basic principles of protein folding is the hairpin. The formation of beta-hairpins, which are the basic components of antiparallel beta-sheets, has been studied extensively in the past decade, but much less is kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c42a69f82c1507395ba0be922d89e09
https://doi.org/10.1021/ja0716960
https://doi.org/10.1021/ja0716960
Publikováno v:
Journal of Molecular Biology. 356:189-208
Aggregation of the SH3 domain of the PI3 kinase, both as a single domain and as a tandem repeat in which the C terminus of one domain is linked to the N terminus of another by a flexible linker of ten glycine/serine residues, has been studied under a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8140126be1d48abc873c5c886d9e0cc0
https://doi.org/10.1016/j.jmb.2005.11.034
https://doi.org/10.1016/j.jmb.2005.11.034
Autor:
Reto Bader, Oliver Zerbe
Publikováno v:
ChemBioChem. 6:1520-1534
Hormones and many other neurotransmitters, growth factors, odorant molecules, and light all present stimuli for a class of membrane-anchored receptors called G protein-coupled receptors (GPCRs). The GPCRs are the largest family of cell-surface recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205e333ac459d7065d8a155e0e100be7
https://doi.org/10.1002/cbic.200400439
https://doi.org/10.1002/cbic.200400439
Publikováno v:
BioNMR in Drug Research. :95-120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f38efca66ab288cbaf19d8eaa1110d41
https://doi.org/10.1002/3527600663.ch5
https://doi.org/10.1002/3527600663.ch5
Publikováno v:
Journal of Molecular Biology. 322:1117-1133
The pancreatic polypeptide (PP), a 36-residue, C-terminally amidated polypeptide hormone is a member of the neuropeptide Y (NPY) family. Here, we have studied the structure and dynamics of bovine pancreatic polypeptide (bPP) when bound to DPC-micelle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29cc76023b9d760c48f575c54151366
https://doi.org/10.1016/s0022-2836(02)00889-6
https://doi.org/10.1016/s0022-2836(02)00889-6
Publikováno v:
Biochemistry. 41:8031-8042
The structure of [Ala(31), Pro(32)]-NPY, a neuropeptide Y mutant with selectivity for the NPY Y(5)-receptor (Cabrele, C., Wieland, H. A., Stidsen, C., Beck-Sickinger, A. G., (2002) Biochemistry XX, XXXX-XXXX (companion paper)), has been characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd1800091a398b78e4c445f7ce99fab
https://doi.org/10.1021/bi0201419
https://doi.org/10.1021/bi0201419
Autor:
Stephen Cauffman, Kevin Felch, M. Blank, Richard J. Temkin, Melanie Rosay, Philipp Borchard, Shane Pawsey, Reto Bader, Leo Tometich, Robert G. Griffin, Robert Schauwecker, Werner E. Maas, Ralph T. Weber
Publikováno v:
Prof. Griffin via Erja Kajosalo
Dynamic Nuclear Polarization (DNP) experiments transfer polarization from electron spins to nuclear spins with microwave irradiation of the electron spins for enhanced sensitivity in nuclear magnetic resonance (NMR) spectroscopy. Design and testing o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffc7a7e570fa57fc97fd24c1adf6eb0
https://pubmed.ncbi.nlm.nih.gov/20449524
https://pubmed.ncbi.nlm.nih.gov/20449524