Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Reto A Schuepbach"'
Autor:
Idoia Busnadiego, Irene A Abela, Pascal M Frey, Daniel A Hofmaenner, Thomas C Scheier, Reto A Schuepbach, Philipp K Buehler, Silvio D Brugger, Benjamin G Hale
Publikováno v:
PLoS Biology, Vol 20, Iss 7, p e3001709 (2022)
Autoantibodies neutralizing the antiviral action of type I interferons (IFNs) have been associated with predisposition to severe Coronavirus Disease 2019 (COVID-19). Here, we screened for such autoantibodies in 103 critically ill COVID-19 patients in
Externí odkaz:
https://doaj.org/article/b3408de1604843568c24aa541f6d426c
Autor:
Nina Maria Burkhard‐Koren, Martina Haberecker, Umberto Maccio, Frank Ruschitzka, Reto A Schuepbach, Annelies S Zinkernagel, Thomas Hardmeier, Zsuzsanna Varga, Holger Moch
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 2, Pp 135-143 (2021)
Abstract Similar to the influenza A pandemic in 1918/1919, the new Coronavirus disease 2019 (COVID‐19) has spread globally. The causes of death in COVID‐19 are frequently compared to a seasonal influenza outbreak. Complete COVID‐19 autopsy stud
Externí odkaz:
https://doaj.org/article/0d0b644479234f828f39f1e8c13c921b
Autor:
Srikanth Mairpady Shambat, Alejandro Gómez-Mejia, Tiziano A Schweizer, Markus Huemer, Chun-Chi Chang, Claudio Acevedo, Judith Bergada-Pijuan, Clément Vulin, Daniel A Hofmaenner, Thomas C Scheier, Sanne Hertegonne, Elena Parietti, Nataliya Miroshnikova, Pedro D Wendel Garcia, Matthias P Hilty, Philipp Karl Buehler, Reto A Schuepbach, Silvio D Brugger, Annelies S Zinkernagel
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010176 (2022)
COVID-19 displays diverse disease severities and symptoms including acute systemic inflammation and hypercytokinemia, with subsequent dysregulation of immune cells. Bacterial superinfections in COVID-19 can further complicate the disease course and a
Externí odkaz:
https://doaj.org/article/04b8749e56df4756990b9960b23bec34
Autor:
Tiziano A Schweizer, Srikanth Mairpady Shambat, Clement Vulin, Sylvia Hoeller, Claudio Acevedo, Markus Huemer, Alejandro Gomez‐Mejia, Chun‐Chi Chang, Jeruscha Baum, Sanne Hertegonne, Eva Hitz, Thomas C Scheier, Daniel A Hofmaenner, Philipp K Buehler, Holger Moch, Reto A Schuepbach, Silvio D Brugger, Annelies S Zinkernagel
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 12, Pp n/a-n/a (2021)
Abstract Objectives Critically ill coronavirus disease 2019 (COVID‐19) patients are characterised by a severely dysregulated cytokine profile and elevated neutrophil counts, impacting disease severity. However, it remains unclear how neutrophils co
Externí odkaz:
https://doaj.org/article/7fd263ea29c7436da33567c8fe95612a
Autor:
Anne-Aylin Sigg, Vanja Zivkovic, Jan Bartussek, Reto A. Schuepbach, Can Ince, Matthias P. Hilty
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-15 (2024)
Abstract Background Circulatory shock, defined as decreased tissue perfusion, leading to inadequate oxygen delivery to meet cellular metabolic demands, remains a common condition with high morbidity and mortality. Rapid restitution and restoration of
Externí odkaz:
https://doaj.org/article/d8db9022d86a4d479741b5ff1941b3ea
Autor:
Nadia Keller, Mathilde Boumasmoud, Federica Andreoni, Andrea Tarnutzer, Manuela von Matt, Thomas C. Scheier, Jana Epprecht, David Weller, Alejandro Gómez-Mejia, Markus Huemer, Donata von Reibnitz, Duveken B. Y. Fontein, Ewerton Marques-Maggio, Reto A. Schuepbach, Srikanth Mairpady-Shambat, Silvio D. Brugger, Annelies S. Zinkernagel
Publikováno v:
mSphere, Vol 9, Iss 9 (2024)
ABSTRACT Group A Streptococcus (GAS) necrotizing fasciitis (NF) is a difficult-to-treat bacterial infection associated with high morbidity and mortality despite extensive surgery and targeted antibiotic treatment. Difficult-to-treat infections are of
Externí odkaz:
https://doaj.org/article/a3445359d53a4465884d6865a96d6df4
Autor:
Mattia M. Müller, Larina Caspar, Onur Sazpinar, Daniel A. Hofmaenner, Rolf Erlebach, Rea Andermatt, Christoph C. Ganter, Reto A. Schuepbach, Pedro D. Wendel-Garcia, Sascha David
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Background Clogging is characterized by a progressive impairment of transmembrane patency in renal replacement devices and occurs due to obstruction of pores by unknown molecules. If citrate-based anti-coagulation is used, clogging can manif
Externí odkaz:
https://doaj.org/article/cd470c3781da427d92470f313a8e54ea
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002736 (2012)
Group A Streptococcus (GAS) has developed a broad arsenal of virulence factors that serve to circumvent host defense mechanisms. The virulence factor DNase Sda1 of the hyperinvasive M1T1 GAS clone degrades DNA-based neutrophil extracellular traps all
Externí odkaz:
https://doaj.org/article/433386330b4345869ed94837c67562e9
Autor:
Maria Angeliki Komninou, Simon Egli, Aurelio Rossi, Jutta Ernst, Michael Krauthammer, Reto A. Schuepbach, Marcos Delgado, Jan Bartussek
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
ObjectiveTo examine the relationship between current and former smoking and the occurrence of delirium in surgical Intensive Care Unit (ICU) patients.MethodsWe conducted a single center, case-control study involving 244 delirious and 251 non-deliriou
Externí odkaz:
https://doaj.org/article/50a03ff26477402d9ac72b07112f5da0
Autor:
Laura Marquardt, Federica Andreoni, Mathilde Boumasmoud, Tiziano A. Schweizer, Dorothea M. Heuberger, Elena Parietti, Sanne Hertegonne, Jana Epprecht, Dario Mattle, Anna K. Raez, Ewerton Marques‐Maggio, Reto A. Schuepbach, Barbara Hasse, Srikanth Mairpady‐Shambat, Silvio D. Brugger, Annelies S. Zinkernagel
Publikováno v:
MicrobiologyOpen, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract Group A streptococcal (GAS; aka Streptococcus pyogenes) meningitis is a fulminant disease associated with high morbidity and mortality. To elucidate the mechanisms underlying the invasiveness of GAS in meningitis, we compared GAS isolates de
Externí odkaz:
https://doaj.org/article/f22407c14bca41b089746197c77dec28