Zobrazeno 1 - 10
of 695
pro vyhledávání: '"Reto, Brun"'
Autor:
Pascal Mäser, Sonja Bernhard, Reto Brun, Christian Burri, Sébastien Gagneux, Manuel W. Hetzel, Marcel Kaiser, Christian Lengeler, Gerd Pluschke, Elisabeth Reus, Matthias Rottmann, Jürg Utzinger, Louisa Warryn, Sergio Wittlin, Jennifer Keiser
Publikováno v:
CHIMIA, Vol 77, Iss 9 (2023)
Thanks to its expertise in clinical research, epidemiology, infectious diseases, microbiology, parasitology, public health, translational research and tropical medicine, coupled with deeply rooted partnerships with institutions in low- and middle-inc
Externí odkaz:
https://doaj.org/article/0810ed06255e4e4c8ea49405fe36758f
Autor:
Dieudonné Tshitenge Tshitenge, Doris Feineis, Virima Mudogo, Marcel Kaiser, Reto Brun, Gerhard Bringmann
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Three unusual heterodimeric naphthylisoquinoline alkaloids, named ealapasamines A-C (1–3), were isolated from the leaves of the tropical plant Ancistrocladus ealaensis J. Léonard. These ‘mixed’, constitutionally unsymmetric dimers are
Externí odkaz:
https://doaj.org/article/d4abafb133174dfe8457a23047975f5f
Autor:
Abdelbasset A. Farahat, Arvind Kumar, Tanja Wenzler, Reto Brun, Ananya Paul, Pu Guo, W. David Wilson, David W. Boykin
New analogs of the antiprotozoal agent Furamidine were prepared utilizing Stille coupling reactions and amidation of the bisnitrile intermediate using lithium bis-trimethylsilylamide. Both the phenyl groups and the furan moiety of furamidine were rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e49411482d3e0a0f86edc530532fd2a
Publikováno v:
Molecules, Vol 20, Iss 9, Pp 16154-16169 (2015)
As part of our ongoing efforts to identify natural products with activity against pathogens causing neglected tropical diseases, we are currently performing an extensive screening of natural product (NP) databases against a multitude of protozoan par
Externí odkaz:
https://doaj.org/article/1943361338c14258b4d205317a1b0730
Publikováno v:
Molecules, Vol 20, Iss 8, Pp 14118-14138 (2015)
Sleeping sickness, Chagas disease, Leishmaniasis, and Malaria are infectious diseases caused by unicellular eukaryotic parasites (“protozoans”). The three first mentioned are classified as Neglected Tropical Diseases (NTDs) by the World Health Or
Externí odkaz:
https://doaj.org/article/5c8ef36e64eb46c39c61c91a87cf4dff
Autor:
Nguyen Phuong Thao, Bui Thi Thuy Luyen, Reto Brun, Marcel Kaiser, Phan Van Kiem, Chau Van Minh, Thomas J. Schmidt, Jong Seong Kang, Young Ho Kim
Publikováno v:
Molecules, Vol 20, Iss 7, Pp 12459-12468 (2015)
Based on our previous finding that certain cembranoid diterpenes possess selective toxicity against protozoan pathogens of tropical diseases such as Trypanosoma and Plasmodium, we have subjected a series of 34 cembranes isolated from soft corals livi
Externí odkaz:
https://doaj.org/article/afb61e0b7e8346dda3e388b7f3c6b496
Publikováno v:
Molecules, Vol 20, Iss 6, Pp 10082-10094 (2015)
Naphthoquinones (NQs) occur naturally in a large variety of plants. Several NQs are highly active against protozoans, amongst them the causative pathogens of neglected tropical diseases such as human African trypanosomiasis (sleeping sickness), Chaga
Externí odkaz:
https://doaj.org/article/1ee8a45de5c74087af4ecddc2587779b
Autor:
Samir Aquino Carvalho, Marcel Kaiser, Reto Brun, Edson Ferreira da Silva, Carlos Alberto Manssour Fraga
Publikováno v:
Molecules, Vol 19, Iss 12, Pp 20374-20381 (2014)
A series of 14 (E)-cinnamic N-acylhydrazone derivatives, designed through molecular hybridization between the (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(4-bromophenyl)prop-2-en-1-one and (E)-3-hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)-7-methoxy-2-nap
Externí odkaz:
https://doaj.org/article/98623cbf9b4646eb85dc23c2536c50be
Autor:
Abraham Wube, Antje Hüfner, Werner Seebacher, Marcel Kaiser, Reto Brun, Rudolf Bauer, Franz Bucar
Publikováno v:
Molecules, Vol 19, Iss 9, Pp 14204-14220 (2014)
A diverse array of 4-(1H)-quinolone derivatives bearing substituents at positions 1 and 2 were synthesized and evaluated for antiprotozoal activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense, and cytotoxicity against L-6 cells
Externí odkaz:
https://doaj.org/article/4f2ebe4320db4dbbaca05d5c928926f0
Publikováno v:
Molecules, Vol 19, Iss 5, Pp 6428-6438 (2014)
In the course of our ongoing screening of plants of the family Asteraceae for antiprotozoal activity, a CH2Cl2-extract from the flowering aerial parts of Achillea ptarmica L. (sneezewort yarrow) was found to be active in vitro against Trypanosoma bru
Externí odkaz:
https://doaj.org/article/8d2a18b15b8d4468b6227dadf79b2e08