Zobrazeno 1 - 10
of 463
pro vyhledávání: '"Retinal binding"'
Autor:
Yujiro Nagasaka, Shoko Hososhima, Naoko Kubo, Takashi Nagata, Hideki Kandori, Keiichi Inoue, Hiromu Yawo
Publikováno v:
Biophysics and Physicobiology, Vol 17 (2020)
Microbial rhodopsin is a large family of membrane proteins having seven transmembrane helices (TM1-7) with an all-trans retinal (ATR) chromophore that is covalently bound to Lys in the TM7. The Trp residue in the middle of TM3, which is homologous to
Externí odkaz:
https://doaj.org/article/6a385a6003b948aab9f82d0074d54f37
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2005 Aug 01. 102(31), 10783-10787.
Externí odkaz:
https://www.jstor.org/stable/3376166
Publikováno v:
Survey of Ophthalmology
Vaccines such as bacille Calmette-Guérin (BCG) are known for their heterologous effects mediated through a number of mechanisms, including trained immunity constituted by monocyte-macrophage based innate immunity. Other events such as direct hematog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e00270dbd3ffc71ebe1fa964f6ccce0
https://doi.org/10.1016/j.survophthal.2021.07.005
https://doi.org/10.1016/j.survophthal.2021.07.005
Akademický článek
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Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 379:166-174
During drug development, potential safety issues can occur at any time. Understanding the cause of a toxicity can help with deciding on how to advance the drug development program. Chemoproteomics provides a way to help understand the cause of a toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba0195acff67bf19e6b680b01ab1b6ca
https://doi.org/10.1124/jpet.121.000614
https://doi.org/10.1124/jpet.121.000614
Publikováno v:
Nature communications, vol 13, iss 1
Microbial channelrhodopsins are light-gated ion channels widely used for optogenetic manipulation of neuronal activity. ChRmine is a bacteriorhodopsin-like cation channelrhodopsin (BCCR) more closely related to ion pump rhodopsins than other channelr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b423c4ab34306b4a0034256a1c4552
https://doi.org/10.1038/s41467-022-32441-7
https://doi.org/10.1038/s41467-022-32441-7
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 8, Iss, Pp 463-480 (2021)
Toxicology Reports, Vol 8, Iss, Pp 463-480 (2021)
Highlights • Injuries with embedded metal fragments are an increasing medical concern. • Metal pellets implanted in the leg muscles of rats solubilize and release metal. • The solubilized metals pass through the kidney and are excreted in the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1b4a8bf32d368b2f978017b1d9a286
http://europepmc.org/articles/PMC7933717
http://europepmc.org/articles/PMC7933717
Autor:
Erix W. Hernández-Rodríguez, Ana L. Montero-Alejo, Marc W. van der Kamp, Andrés M. Escorcia, Julio Caballero
Publikováno v:
Hernández-Rodríguez, E W, Escorcia Cabrera, A M, Van Der Kamp, M W, Montero-Alejo, A L & Caballero, J 2020, ' Multi-scale Simulation Reveals that an Amino Acid Substitution Increases Photosensitizing Reaction Inputs in Rhodopsins ', Journal of Computational Chemistry . https://doi.org/10.1002/jcc.26392
Evaluating the availability of molecular oxygen (O2) and energy of excited states in the retinalbinding site of rhodopsin is a crucial challenging first step to understand photosensitizing reactionsin wild-type (WT) and mutant rhodopsins by absorbing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0b999ef398a2db60bb77ccdb4f0e09
https://doi.org/10.1002/jcc.26392
https://doi.org/10.1002/jcc.26392
Publikováno v:
Biochemistry. 59:2602-2607
The visual pigments of humans contain 11-cis retinal as the chromophore of light perception, and its photoisomerization to the all-trans form initiates visual excitation in our eyes. It is well known that three isomeric states of retinal (11-cis, all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4392bd8689a04eb5ca9910cd91e4ec6
https://doi.org/10.1021/acs.biochem.0c00394
https://doi.org/10.1021/acs.biochem.0c00394
Autor:
Hiromu Yawo, Shoko Hososhima, Keiichi Inoue, Hideki Kandori, Naoko Kubo, Yujiro Nagasaka, Takashi Nagata
Publikováno v:
Biophysics and Physicobiology, Vol 17 (2020)
Biophysics and Physicobiology
Biophysics and Physicobiology
Microbial rhodopsin is a large family of membrane proteins having seven transmembrane helices (TM1-7) with an all-trans retinal (ATR) chromophore that is covalently bound to Lys in the TM7. The Trp residue in the middle of TM3, which is homologous to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab4cf23fcf1453e234fddcdb4207cdc
https://doi.org/10.2142/biophysico.bsj-2020007
https://doi.org/10.2142/biophysico.bsj-2020007