Zobrazeno 1 - 10
of 11 075
pro vyhledávání: '"Retinal Ganglion Cell"'
Autor:
Lin-Ping Xue, Hai-Song Feng
Publikováno v:
International Journal of Ophthalmology, Vol 18, Iss 1, Pp 39-50 (2025)
AIM: To explore the neuroprotective effects of high mobility group box 2 (HMGB2) knockdown on retinal ganglion cells (RGCs) in the retinal ischemia-reperfusion injury (RIRI). METHODS: Oxygen-glucose deprivation (OGD)-injured RGCs from postnatal three
Externí odkaz:
https://doaj.org/article/f2ac079e4187446b9636292a612916dc
Autor:
Maharani, Arief Sjamsulaksan Kartasasmita, Fifin Luthfia Rahmi, Arief Wildan, Hermawan Istiadi, Annisa Dentin Nugroho, Banundari Rachmawati
Publikováno v:
Journal of Advanced Pharmaceutical Technology & Research, Vol 15, Iss 4, Pp 304-308 (2024)
Chronic hyperglycemia activates pathological molecular pathways, causing high inflammatory mediators, oxidative stress, and growth factors. This process contributes to retinal ganglion cell (RGC) apoptosis through the expression of N-methyl-D-asparta
Externí odkaz:
https://doaj.org/article/4e37d39cb8a24607af12f08b6619338b
Autor:
Xinxin Hu, Juntao Zhang, Haixia Ma, Wei Lian, Wenqiu Song, Chao Du, Shengcan Chen, Dandan Wang, Jiaqi Wei, Qinkang Lu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Glaucoma is a leading cause of irreversible visual impairment worldwide, characterized by the progressive death of retinal ganglion cells (RGCs). Deubiquitinating enzyme (DUB) inhibitors have shown promise as pharmacological interventions fo
Externí odkaz:
https://doaj.org/article/544375f78e8145beb604ce304fe41fa8
Autor:
Alexander M. Warwick, Howard M. Bomze, Luyu Wang, Ying Hao, Sandra S. Stinnett, Sidney M. Gospe
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Continuous exposure to environmental hypoxia (11% O2) has been shown to markedly slow the progressive degeneration of retinal ganglion cells (RGCs) in a mouse model of mitochondrial optic neuropathy with RGC-specific deletion of the key mito
Externí odkaz:
https://doaj.org/article/ea283ac2ccef4825baad27145c386c9a
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-9 (2024)
Abstract Motor neuron loss is well recognized in amyotrophic lateral sclerosis (ALS), but research on retinal ganglion cells (RGCs) is limited. Ocular symptoms are generally not considered classic ALS symptoms, although RGCs and spinal motor neurons
Externí odkaz:
https://doaj.org/article/f1c112580f914795a52c0e0dda1d6389
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 9, Pp 1606-1613 (2024)
AIM: To determine whether etomidate (ET) has a protective effect on retinal ganglion cells (RGCs) injured with hydrogen peroxide (H2O2) and to explore the potential mechanism underlying the antioxidative stress effect of ET. METHODS: Cultured RGCs we
Externí odkaz:
https://doaj.org/article/0c4319b6e8cf46199b758e6fcbdd29ce
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-4 (2024)
Abstract Protocadherin 19 (Pcdh19) is a homophilic cell adhesion molecule and is involved in a variety of neuronal functions. Here, we tested whether Pcdh19 has a regulatory role in axon guidance using the developing Xenopus retinotectal system. We p
Externí odkaz:
https://doaj.org/article/1dacf83dd356457aac77ce0a4fae5477
Autor:
Dan Wang, Jiajia Yuan, Hong-Li Liu, Shi-lian Li, Nan Ma, Meng-lan Chen, Hua Yuan, Hong Jie, Bin Li, Tao Zhang
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background To investigate the peripapillary retinal nerve fibre layer (RNFL) thickness changes and analyse factors associated with visual recovery of G11778A Leber hereditary optic neuropathy (LHON) patients. Methods Patients diagnosed with
Externí odkaz:
https://doaj.org/article/203acd015728441e8c0b5e05c94d53c0
Autor:
Soheila Nazari
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36673- (2024)
Spiking networks, the third generation of neural networks, are presented as low-power consumption machines with higher cognitive ability, one of the main concerns in intelligence machines. In fact, neuromorphic systems are hardware implementations of
Externí odkaz:
https://doaj.org/article/f671d0bc3f9a4e988c770154d1df6f67