In vitro profiling of opioid ligands using the cAMP formation inhibition assay and the β-arrestin2 recruitment assay: No two ligands have the same profile.

Autor: Kuo A; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia., Magiera J; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia., Rethwan N; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia., Andersson Å; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia., Leen Lam A; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia., Wyse B; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia., Meutermans W; VAST Bioscience Pty Ltd, Toowong, Brisbane, QLD, Australia., Lewis R; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia., Smith M; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia. Electronic address: maree.smith@uq.edu.au.

Publikováno v: European journal of pharmacology [Eur J Pharmacol] 2020 Apr 05; Vol. 872, pp. 172947. Date of Electronic Publication: 2020 Jan 25.

Pharmacokinetics and Safety of Oliceridine Fumarate Injection in Chinese Patients with Chronic Non-Cancer Pain: A Phase I, Single-Ascending-Dose, Open-Label Clinical Trial.

Autor: Ni, Yuncheng, Huang, Ranglang, Yang, Shuang, Yang, Xiao Yan, Zeng, Shan, Yao, An, Huang, Jie, Yang, Guoping

Publikováno v: Drug Design, Development & Therapy; Jul2024, Vol. 18, p2729-2743, 15p

Activation of the μ‐opioid receptor by alicyclic fentanyls: Changes from high potency full agonists to low potency partial agonists with increasing alicyclic substructure.

Autor: Åstrand, Anna, Vikingsson, Svante, Jakobsen, Ingrid, Björn, Niclas, Kronstrand, Robert, Gréen, Henrik

Publikováno v: Drug Testing & Analysis; Jan2021, Vol. 13 Issue 1, p169-174, 6p