Zobrazeno 1 - 10
of 525
pro vyhledávání: '"Ret gene"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Papillary thyroid carcinoma (PTC) is generally considered a highly indolent endocrine malignancy, often accompanied by cervical lymph node metastasis and rarely involving distant metastases. We present a rare case of a 37-year-old woman with PTC, who
Externí odkaz:
https://doaj.org/article/5634b2e0489545daad9374d73c4b55d6
Autor:
Jia-Xuan Huai, Fang Wang, Wen-Hui Zhang, Yan Lou, Gao-Xiang Wang, Li-Ji Huang, Jing Sun, Xi-Qiao Zhou
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Medullary Thyroid Carcinoma (MTC), a neuroendocrine malignancy that arises from the calcitonin-secreting parafollicular C-cells of the thyroid, constitutes a minor yet impactful fraction of thyroid malignancies. Distinguished by its propensity for ag
Externí odkaz:
https://doaj.org/article/4e0296d1089946398d00110c7c11f0ee
Publikováno v:
Сибирский онкологический журнал, Vol 23, Iss 2, Pp 133-138 (2024)
Background. The use of the modern targeted drugs in patients with non-small-cell lung cancer (NSCLC) with certain somatic alterations (genetic alterations in EGFR, ALK, ROS1, BRAF, RET genes, etc.) provides a significant increase in overall and disea
Externí odkaz:
https://doaj.org/article/44c6ff27b6dd4ab285c7f9f699f1123c
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
RET fusions were discovered in non-small cell lung cancer (NSCLC), and the efficacy of RET-targeted treatment in these patients has been previously established. However, patients with required resistance to RET-TKIs have limited treatment options. He
Externí odkaz:
https://doaj.org/article/fe95af7ab29943a4b36ee8ca14a28fee
Autor:
Suzanne Murray, Vivek Subbiah, Steven I. Sherman, Sophie Péloquin, Anthony Sireci, Christian Grohé, Patrick Bubach, Patrice Lazure
Publikováno v:
Thyroid Research, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Background The discovery of driver oncogenes for thyroid carcinomas and the identification of genomically targeted therapies to inhibit those oncogenes have altered the treatment algorithm in thyroid cancer (TC), while germline testing for R
Externí odkaz:
https://doaj.org/article/207fa35c8be54dfb9c44c1c5719d9e41
Publikováno v:
Zhongguo quanke yixue, Vol 26, Iss 14, Pp 1794-1798 (2023)
Multiple endocrine adenomatosis type 2A (MEN2A) is a subtype of multiple endocrine adenomatosis type 2, which is clinically characterized by medulloid thyroid carcinoma (MTC) , pheochromocytoma (PHEO) , and hyperparathyroidism, and has been reported
Externí odkaz:
https://doaj.org/article/08bb6dab178945f1a25aeee576af0b4e
Publikováno v:
AIMS Neuroscience, Vol 9, Iss 1, Pp 128-149 (2022)
Enteric neurons and ganglia are derived from vagal and sacral neural crest cells, which undergo migration from the neural tube to the gut wall. In the gut wall, they first undergo rostrocaudal migration followed by migration from the superficial to d
Externí odkaz:
https://doaj.org/article/868ed2335f7542cbb8b9ed9e541790ba
Publikováno v:
Waike lilun yu shijian, Vol 26, Iss 06, Pp 522-527 (2021)
Objective To investigate the association between RET genotype and disease phenotype in the patients with hereditary medullary thyroid carcinoma (HMTC). Methods A total of 13 patients diagnosed as HMTC and undergoing surgical treatment for thyroid car
Externí odkaz:
https://doaj.org/article/b527564f6f284edea548e1a9001b6fe1
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Lung cancer has very high morbidity and mortality worldwide, and the prognosis is not optimistic. Previous treatments for non-small cell lung cancer (NSCLC) have limited efficacy, and targeted drugs for some gene mutations have been used in NSCLC wit
Externí odkaz:
https://doaj.org/article/1041f357871f4d36a95b9d7e99314c9b
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-8 (2021)
Abstract The recent approvals by the Food and Drug Administration several tumor-agnostic drugs have resulted in a paradigm shift in cancer treatment from an organ/histology-specific strategy to biomarker-guided approaches. RET gene fusions are oncoge
Externí odkaz:
https://doaj.org/article/67f46a88af534e2eaafca57707e604e2