Zobrazeno 1 - 10
of 597
pro vyhledávání: '"Restriction-modification systems"'
Publikováno v:
eLife, Vol 13 (2024)
A comprehensive census of McrBC systems, among the most common forms of prokaryotic Type IV restriction systems, followed by phylogenetic analysis, reveals their enormous abundance in diverse prokaryotes and a plethora of genomic associations. We foc
Externí odkaz:
https://doaj.org/article/b309354c91c44c478f2a7f709132435b
Autor:
Susu Jiang, Ke Chen, Yingying Wang, Yueying Zhang, Yaru Tang, Wanqiu Huang, Xiaolin Xiong, Shi Chen, Chao Chen, Lianrong Wang
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT DndABCDE-catalyzed DNA phosphorothioation (PT), in which the nonbridging oxygen is swapped with a sulfur atom, was first identified in the bacterial genome. Usually, this modification gene cluster is paired with a restriction module consisti
Externí odkaz:
https://doaj.org/article/e9da0fdf5cb54d5294d80b3d42b26a05
Autor:
Qun Gao, Shuwei Lu, Yuwei Wang, Longgui He, Mingshu Wang, Renyong Jia, Shun Chen, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Juan Huang, Sai Mao, Xumin Ou, Di Sun, Bin Tian, Anchun Cheng
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Epigenetics modulates expression levels of various important genes in both prokaryotes and eukaryotes. These epigenetic traits are heritable without any change in genetic DNA sequences. DNA methylation is a universal mechanism of epigenetic regulatio
Externí odkaz:
https://doaj.org/article/eaa175ddf10648edb2c51edb344ac763
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Restriction modification (RM) systems are known to provide a strong barrier to the exchange of DNA between and within bacterial species. Likewise, DNA methylation is known to have an important function in bacterial epigenetics regulating essential pa
Externí odkaz:
https://doaj.org/article/d416a7d147d84140b798f7fd6b574c89
Publikováno v:
Military Medical Research, Vol 9, Iss 1, Pp 1-11 (2022)
Abstract Bacteria can evolve rapidly by acquiring new traits such as virulence, metabolic properties, and most importantly, antimicrobial resistance, through horizontal gene transfer (HGT). Multidrug resistance in bacteria, especially in Gram-negativ
Externí odkaz:
https://doaj.org/article/d5134c4c31ad4284b79cb6dbaa5a1daf
Autor:
Luke V. Blakeway, Aimee Tan, Joseph A. Jurcisek, Lauren O. Bakaletz, John M. Atack, Ian R. Peak, Kate L. Seib
Publikováno v:
BMC Microbiology, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background Moraxella catarrhalis is a leading cause of otitis media (OM) and chronic obstructive pulmonary disease (COPD). M. catarrhalis contains a Type III DNA adenine methyltransferase (ModM) that is phase-variably expressed (i.e., its ex
Externí odkaz:
https://doaj.org/article/5ec23ad9abc04ad38a899e8299026829
Akademický článek
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Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Restriction-modification (R-M) systems protect bacteria and archaea from attacks by bacteriophages and archaeal viruses. An R-M system specifically recognizes short sites in foreign DNA and cleaves it, while such sites in the host
Externí odkaz:
https://doaj.org/article/b4295dda48674461aa2ca1d76a6dca37
Akademický článek
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Autor:
Florian R. Zbinden, Megan De Ste Croix, Denis Grandgirard, Richard D. Haigh, Irene Vacca, Roxana Zamudio, Emily C. A. Goodall, Roger Stephan, Marco R. Oggioni, Stephen L. Leib
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Background:L. monocytogenes meningoencephalitis has a mortality rate of up to 50% and neurofunctional sequelae are common. Type I restriction-modification systems (RMS) are capable of adding methyl groups to the host genome. Some contain multiple seq
Externí odkaz:
https://doaj.org/article/232b76a7ff134a6a874b1a3ea8474134