Predictions and experimental tests of a new biophysical model of the mammalian respiratory oscillator

Autor: Ryan S Phillips, Hidehiko Koizumi, Yaroslav I Molkov, Jonathan E Rubin, Jeffrey C Smith

Publikováno v: eLife, Vol 11 (2022)

Previously our computational modeling studies (Phillips et al., 2019) proposed that neuronal persistent sodium current (INaP) and calcium-activated non-selective cation current (ICAN) are key biophysical factors that, respectively, generate inspirato

Externí odkaz: https://doaj.org/article/dd1515b461b44c10a4cf3a5fd3aeda58

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Control of respiration in fish, amphibians and reptiles

Autor: E.W. Taylor, C.A.C. Leite, D.J. McKenzie, T. Wang

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 43, Iss 5, Pp 409-424 (2010)

Fish and amphibians utilise a suction/force pump to ventilate gills or lungs, with the respiratory muscles innervated by cranial nerves, while reptiles have a thoracic, aspiratory pump innervated by spinal nerves. However, fish can recruit a hypobran

Externí odkaz: https://doaj.org/article/44c3cb8e0f4d453e8ca3f1582f1566f9

Advancing respiratory-cardiovascular physiology with the working heart-brainstem preparation over 25 years

Autor: Julian F. R. Paton, Benedito H. Machado, Davi J. A. Moraes, Daniel B. Zoccal, Ana P. Abdala, Jeffrey C. Smith, Vagner R. Antunes, David Murphy, Mathias Dutschmann, Rishi R. Dhingra, Robin McAllen, Anthony E. Pickering, Richard J. A. Wilson, Trevor A. Day, Nicole O. Barioni, Andrew M. Allen, Clément Menuet, Joseph Donnelly, Igor Felippe, Walter M. St‐John

Publikováno v: et al. 2022, ' Advancing respiratory–cardiovascular physiology with the working heart–brainstem preparation over 25 years ', The Journal of Physiology, vol. 600, no. 9, pp. 2049-2075 . https://doi.org/10.1113/JP281953
The Journal of Physiology
The Journal of Physiology, 2022, 600 (9), pp.2049-2075. ⟨10.1113/JP281953⟩
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Twenty-five years ago, a new physiological preparation called the working heart–brainstem preparation (WHBP) was introduced with the claim it would provide a new platform allowing studies not possible before in cardiovascular, neuroendocrine, auton

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdefc7f849a5da0662135ec76208f3fc
https://pubmed.ncbi.nlm.nih.gov/35294064