Výsledky vyhledávání - "Respiratory Medicine/Respiratory Pediatrics"

Procalcitonin and C-Reactive Protein for invasive bacterial pneumonia diagnosis among children in Mozambique, a malaria-endemic area

Autor: Díez-Padrisa, Núria, Bassat Orellana, Quique, Machevo, Sonia, Quintó, Llorenç, Morais, Luis, Nhampossa, Tacilta, O'Callaghan Gordo, Cristina, Torres Martí, Antoni, Alonso, Pedro, Roca i Aparicio, Anna

Publikováno v: PLoS ONE
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE, Vol 5, Iss 10, p e13226 (2010)

Background: Pneumonia is the major cause of mortality and morbidity in children worldwide. Procalcitonin (PCT) and C-reactive protein (CRP) are used in developed countries to differentiate between viral and bacterial causes of pneumonia. Validity of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ad74127e89bb57699da87607df93880f
http://hdl.handle.net/2445/21444

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Detection of Mycoplasma pneumoniae in Simulated and True Clinical Throat Swab Specimens by Nanorod Array-Surface-Enhanced Raman Spectroscopy

Autor: Jeremy D. Driskell, Yiping Zhao, Ralph A. Tripp, Ken B. Waites, Suzanne L. Hennigan, Duncan C. Krause, Richard A. Dluhy

Publikováno v: PLoS ONE
PLoS ONE, Vol 5, Iss 10, p e13633 (2010)

The prokaryote Mycoplasma pneumoniae is a major cause of respiratory disease in humans, accounting for 20% of all community-acquired pneumonia and the leading cause of pneumonia in older children and young adults. The limitations of existing options

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12948b2084b51db24d448ce943847c69
http://europepmc.org/articles/PMC2964322

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Intracellular persisting Staphylococcus aureus is the major pathogen in recurrent tonsillitis

Autor: Hagen Frickmann, Claudia Maletzki, Bernd Kreikemeyer, Merit Krause, Gerhard Stropahl, Andreas E. Zautner, Andreas Podbielski, Silva Holtfreter, Hans Wilhelm Pau

Publikováno v: PLoS ONE, Vol 5, Iss 3, p e9452 (2010)
PLoS ONE

BackgroundThe two major indications for tonsillectomy are recurrent tonsillitis (RT) and peritonsillar abscess (PTA). Unlike PTAs, which are primarily treated surgically, RT is often cured by tonsillectomy only after a series of failed drug therapy a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e0077a0175e0657815987c8f83f028
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20209109/?tool=EBI

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Disordered microbial communities in asthmatic airways

Autor: Paul Cardenas, Conor Burke, William O.C.M. Cookson, Cara Bossley, Aaron Ervine, Miriam F. Moffatt, Len Poulter, Markus Hilty, Helder Pedro, Andrew Bush, Lior Pachter, Jane C. Davies

Publikováno v: e8578
PLoS ONE
PLoS ONE, Vol 5, Iss 1, p e8578 (2010)

Background: A rich microbial environment in infancy protects against asthma [1], [2] and infections precipitate asthma exacerbations [3]. We compared the airway microbiota at three levels in adult patients with asthma, the related condition of COPD,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9e6b2c5a56ebefadd25c59bbe9081f
http://hdl.handle.net/10044/1/4679

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Cytokine profiles in asthma families depend on age and phenotype

Autor: David Kutschke, Koustav Ganguly, Matthias Wjst, Katrin Pukelsheim, Tobias Stoeger

Publikováno v: PLoS ONE 5:e14299 (2010)
PLoS ONE
PLoS ONE, Vol 5, Iss 12, p e14299 (2010)

Circulating cytokine patterns may be relevant for the diagnosis of asthma, for the discrimination of certain phenotypes, and prognostic factors for exacerbation of disease. METHODOLOGY/PRINCIPAL FINDINGS: In this study we investigated serum samples f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018e3e7ae97769588fbc94c146c0a0d0
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=5028

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Critical structural and functional roles for the N-terminal insertion sequence in surfactant protein B analogs

Autor: Zhengdong Wang, Chun-Ling Jung, Robert H. Notter, Alan J. Waring, Frans J. Walther, Andrew P. Clark, Piotr Ruchala, Larry M. Gordon, Wesley M. Smith, José M. Hernández-Juviel, Shantanu Sharma

Publikováno v: PLoS ONE, Vol 5, Iss 1, p e8672 (2010)
PLoS ONE

Background Surfactant protein B (SP-B; 79 residues) belongs to the saposin protein superfamily, and plays functional roles in lung surfactant. The disulfide cross-linked, N- and C-terminal domains of SP-B have been theoretically predicted to fold as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb851ef920e6b6fa73d23eefb15d02a
http://europepmc.org/articles/PMC2805716?pdf=render

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The Synthetic Bacterial Lipopeptide Pam3CSK4 Modulates Respiratory Syncytial Virus Infection Independent of TLR Activation

Autor: Lot de Witte, Karl-Heinz Wiesmüller, Teunis B. H. Geijtenbeek, D. Tien Nguyen, Albert D. M. E. Osterhaus, Rik L. de Swart, Selma Yüksel, Martin Ludlow

Publikováno v: PLoS Pathogens (print), 6(8). Public Library of Science
PLoS Pathogens, Vol 6, Iss 8, p e1001049 (2010)
PLoS Pathogens, 6(8). Public Library of Science
PLoS Pathogens
PLoS pathogens, 6(8). Public Library of Science

Respiratory syncytial virus (RSV) is an important cause of acute respiratory disease in infants, immunocompromised subjects and the elderly. However, it is unclear why most primary RSV infections are associated with relatively mild symptoms, whereas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3c4fa1b25eb3c3f9020ae0f34f6905
https://pure.eur.nl/en/publications/f399c7df-6776-4fca-a765-aa4b5fdd8441

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Nutrient Availability as a Mechanism for Selection of Antibiotic Tolerant Pseudomonas aeruginosa within the CF Airway

Autor: Ferric C. Fang, Mikkel Klausen, Anthony R. Richardson, Samuel I. Miller, Daniel J. Hassett, David A. Stahl, Laura S. Houston, Lucas R. Hoffman, Hemantha D. Kulasekara, Willm Martens-Habbena, Jane L. Burns

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 6, Iss 1, p e1000712 (2010)

Microbes are subjected to selective pressures during chronic infections of host tissues. Pseudomonas aeruginosa isolates with inactivating mutations in the transcriptional regulator LasR are frequently selected within the airways of people with cysti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8ef0f000301649c313acefde31fef5
http://europepmc.org/articles/PMC2795201

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A model analysis of arterial oxygen desaturation during apnea in preterm infants

Autor: Scott A. Sands, Malcolm R. Davidson, Bradley A. Edwards, Philip J. Berger, Vanessa J. Kelly, Malcolm Howard Wilkinson

Publikováno v: PLoS Computational Biology, Vol 5, Iss 12, p e1000588 (2009)
PLoS Computational Biology

Rapid arterial O2 desaturation during apnea in the preterm infant has obvious clinical implications but to date no adequate explanation for why it exists. Understanding the factors influencing the rate of arterial O2 desaturation during apnea () is c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8461c31f3b865e188fe9ab3c3d8854
http://europepmc.org/articles/PMC2778953?pdf=render

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Engineered Common Cold Virus Helps Cultured Cystic Fibrosis Tissues Clear Mucus

Autor: Zhang, L, Button, B, Gabriel, SE, Burkett, S, Yan, Y, Skiadopoulos, MH, Dang, YL, Vogel, LN, McKay, T, Mengos, A, Boucher, RC, Collins, PL, Pickles, RJ, Philipson, L

Publikováno v: PLoS Biology
PLoS Biology, Vol 7, Iss 7, p e1000155 (2009)

Delivering CFTR to ciliated cells of cystic fibrosis (CF) patients fully restores ion and fluid transport to the lumenal surface of airway epithelium and returns mucus transport rates to those of non-CF airways.
Dysfunction of CFTR in cystic fib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96090e3ced287e66fcef05a792a9c02
https://e-space.mmu.ac.uk/615345/

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