Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Reshub Bahri"'
Autor:
Manish Kumar, David Molkentine, Jessica Molkentine, Kathleen Bridges, Tongxin Xie, Liangpeng Yang, Andrew Hefner, Meng Gao, Reshub Bahri, Annika Dhawan, Mitchell J. Frederick, Sahil Seth, Mohamed Abdelhakiem, Beth M. Beadle, Faye Johnson, Jing Wang, Li Shen, Timothy Heffernan, Aakash Sheth, Robert L. Ferris, Jeffrey N. Myers, Curtis R. Pickering, Heath D. Skinner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Mutations in histone acetyltransferases (HATs) CREBBP and EP300 are generally thought to lead to decreased function or absence of protein product. Here the authors describe a gain of function of several CREBBP mutations leading to baseline hyper-acet
Externí odkaz:
https://doaj.org/article/9e9b057abf944363949c648ff88a38f3
Autor:
Heath D. Skinner, Raymond E. Meyn, Curtis R. Pickering, Kathryn A. Mason, Howard D. Thames, Beth M. Beadle, Aakash Sheth, Vlad Sandulache, Phillip M. Pifer, Mohamed Abdelhakiem, Liangpeng Yang, Manish Kumar, Andrew J. Hefner, Reshub Bahri, Annika Dhawan, David R. Valdecanas, Kathleen A. Bridges, Jessica M. Molkentine, David P. Molkentine
Supplementary Data from p16 Represses DNA Damage Repair via a Novel Ubiquitin-Dependent Signaling Cascade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5a277048ff4f3713318e86b43be1de
https://doi.org/10.1158/0008-5472.22431283.v1
https://doi.org/10.1158/0008-5472.22431283.v1
Autor:
Heath D. Skinner, Raymond E. Meyn, Curtis R. Pickering, Kathryn A. Mason, Howard D. Thames, Beth M. Beadle, Aakash Sheth, Vlad Sandulache, Phillip M. Pifer, Mohamed Abdelhakiem, Liangpeng Yang, Manish Kumar, Andrew J. Hefner, Reshub Bahri, Annika Dhawan, David R. Valdecanas, Kathleen A. Bridges, Jessica M. Molkentine, David P. Molkentine
Squamous cell carcinoma driven by human papillomavirus (HPV) is more sensitive to DNA-damaging therapies than its HPV-negative counterpart. Here, we show that p16, the clinically used surrogate for HPV positivity, renders cells more sensitive to radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b9959bb71a691ecc3132dd0d64975f6
https://doi.org/10.1158/0008-5472.c.6513859.v1
https://doi.org/10.1158/0008-5472.c.6513859.v1
Autor:
David P. Molkentine, Jessica M. Molkentine, Kathleen A. Bridges, David R. Valdecanas, Annika Dhawan, Reshub Bahri, Andrew J. Hefner, Manish Kumar, Liangpeng Yang, Mohamed Abdelhakiem, Phillip M. Pifer, Vlad Sandulache, Aakash Sheth, Beth M. Beadle, Howard D. Thames, Kathryn A. Mason, Curtis R. Pickering, Raymond E. Meyn, Heath D. Skinner
Publikováno v:
Cancer Res
Squamous cell carcinoma driven by human papillomavirus (HPV) is more sensitive to DNA-damaging therapies than its HPV-negative counterpart. Here, we show that p16, the clinically used surrogate for HPV positivity, renders cells more sensitive to radi
Autor:
Reshub Bahri, Annika Dhawan, Liangpeng Yang, Li Shen, Jessica M. Molkentine, Andrew J. Hefner, Jing Wang, Robert L. Ferris, Beth M. Beadle, Meng Gao, Kathleen Bridges, Mohamed Abdelhakiem, Aakash Sheth, Manish Kumar, Sahil Seth, Heath D Skinner, Faye M. Johnson, Jeffrey N. Myers, Curtis R. Pickering, Timothy P. Heffernan, Tongxin Xie, David Molkentine, Mitchell J. Frederick
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Despite radiation forming the curative backbone of over 50% of malignancies, there are no genomically-driven radiosensitizers for clinical use. Herein we perform in vivo shRNA screening to identify targets generally associated with radiation response