Multifunctional Nanovaccine Sensitizes Breast Cancer to Immune Checkpoint Therapy.

Autor: Peres, Carina, Matos, Ana I., Carreira, Bárbara, Moura, Liane I. F., Kleiner, Ron, Vaskovich‐Koubi, Daniella, Reshef, Keren, Dulberg, Shai, Verdial, Mafalda, Conniot, João, Afonso, Marta B., Acúrcio, Rita C., Basto, Afonso P., Mensurado, Sofia, Silva‐Santos, Bruno, Santos, Susana Constantino Rosa, Viana, Ana S., Silva, Liana C., Rodrigues, Cecília M. P., Préat, Véronique

Publikováno v: Advanced Functional Materials; 8/14/2024, Vol. 34 Issue 33, p1-23, 23p

Crosslinking of Ly6a metabolically reprograms CD8 T cells for cancer immunotherapy.

Autor: Maliah A; Department of Human Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Santana-Magal N; Department of Pathology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Parikh S; The Ragon Institute of Mass General, MIT and Harvard 600/625 Main Street, Cambridge, MA, USA., Gordon S; Department of Human Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Reshef K; Department of Pathology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Sade Y; Department of Human Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Khateeb A; Department of Pathology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Richter A; Department of Pathology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Gutwillig A; Department of Pathology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Parikh R; Department of Human Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Golan T; Department of Human Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Krissi M; Department of Human Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Na M; Department of Pathology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Binshtok G; Department of Human Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Manich P; Department of Human Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Elkoshi N; Department of Human Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Grisaru-Tal S; Department of Clinical Microbiology and Immunology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Zemser-Werner V; Institute of Pathology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel., Brenner R; Institute of Oncology, E. Wolfson Medical Center, Holon, Israel., Vaknine H; Institute of Pathology, E. Wolfson Medical Center, Holon, Israel., Nizri E; Peritoneal Surface Malignancies and Melanoma Unit, Department of Surgery A, Tel-Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel., Moyal L; Felsenstein Medical Research Center, Tel-Aviv University and the Division of Dermatology, Rabin Medical Center, Petach Tikva, Israel., Amitay-Laish I; Felsenstein Medical Research Center, Tel-Aviv University and the Division of Dermatology, Rabin Medical Center, Petach Tikva, Israel., Rosemberg L; School of Zoology, Tel Aviv University, Tel Aviv-Yafo, Israel., Munitz A; Department of Clinical Microbiology and Immunology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Kronfeld-Schor N; School of Zoology, Tel Aviv University, Tel Aviv-Yafo, Israel., Shifrut E; Department of Pathology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Faculty of Life Sciences, School of Neurobiology, Biochemistry and Biophysics, Tel Aviv University, Tel Aviv, Israel.; Dotan Center for Advanced Therapies, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel., Kobiler O; Department of Clinical Microbiology and Immunology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Madi A; Department of Pathology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Geiger T; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel., Carmi Y; Department of Pathology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. yaroncarmi@tauex.tau.ac.il., Levy C; Department of Human Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. carmitlevy@tauex.tau.ac.il.

Publikováno v: Nature communications [Nat Commun] 2024 Sep 27; Vol. 15 (1), pp. 8354. Date of Electronic Publication: 2024 Sep 27.