Zobrazeno 1 - 10
of 1 994
pro vyhledávání: '"Research Highlight"'
Publikováno v:
Cell
Cell Res
Cell Res
Regulatable CAR platforms could circumvent toxicities associated with CAR-T therapy, but existing systems have shortcomings including leakiness and attenuated activity. Here, we present SNIP CARs, a protease-based platform for regulating CAR activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ce4052ade846a5ea6638b050cb8e1c
https://pubmed.ncbi.nlm.nih.gov/35483375
https://pubmed.ncbi.nlm.nih.gov/35483375
Publikováno v:
Genes Dis
Genes & diseases, vol 10, iss 1
Genes & diseases, vol 10, iss 1
Although extensively studied, it is unknown what is the major cellular energy driving tumor metastasis after anti-cancer radiotherapy. Metabolic reprogramming is one of the fundamental hallmarks in carcinogenesis and tumor progression featured with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7211e8680d34788093b0f9a7d9b68689
https://doi.org/10.1016/j.gendis.2022.07.019
https://doi.org/10.1016/j.gendis.2022.07.019
Autor:
Aurelien Tripp, George Poulogiannis
Publikováno v:
Cell Res
Metabolic reprogramming is a hallmark of cancer. However, systematic characterizations of metabolites in triple-negative breast cancer (TNBC) are still lacking. Our study profiled the polar metabolome and lipidome in 330 TNBC samples and 149 paired n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9665c414e23b210b9cecf390dfd4c05
https://pubmed.ncbi.nlm.nih.gov/35105939
https://pubmed.ncbi.nlm.nih.gov/35105939
Publikováno v:
Neurosci Bull
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b24fbe579e3cadf65f19d1eacb05e3
https://doi.org/10.1007/s12264-022-00854-5
https://doi.org/10.1007/s12264-022-00854-5
Autor:
Xiaoqing Lu, Liwei An, Guangjian Fan, Lijuan Zang, Weiyi Huang, Junjian Li, Jun Liu, Weiyu Ge, Yuwei Huang, Jingxuan Xu, Shaoqian Du, Yuan Cao, Tianhao Zhou, Huijing Yin, Li Yu, Shi Jiao, Hongxia Wang
Publikováno v:
Cell Res
TSPAN family of proteins are generally considered to assemble as multimeric complexes on the plasma membrane. Our previous work uncovered that TSPAN8 can translocate into the nucleus as a membrane-free form, a process that requires TSPAN8 palmitoylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a9d474e4ee2f75be81aaa31fa6bbc8
https://doi.org/10.1038/s41422-022-00628-8
https://doi.org/10.1038/s41422-022-00628-8
Publikováno v:
Neurosci Bull
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f4dbb6214e1ffce97eeaf5019ba994
https://doi.org/10.1007/s12264-022-00822-z
https://doi.org/10.1007/s12264-022-00822-z
Publikováno v:
Cell
Cell Res
Cell Res
NLRP6 is important in host defense by inducing functional outcomes including inflammasome activation and interferon production. Here we show that NLRP6 undergoes liquid-liquid phase separation (LLPS) upon interaction with dsRNA in vitro and in cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762057c24cec889b9d129b3628a3dc44
https://pubmed.ncbi.nlm.nih.gov/34678144
https://pubmed.ncbi.nlm.nih.gov/34678144
Autor:
Oliver Daumke, Gary R. Lewin
Publikováno v:
Cell Res
The lateral segregation of membrane constituents into functional microdomains, conceptually known as lipid raft, is a universal organization principle for cellular membranes in both prokaryotes and eukaryotes. The widespread Stomatin, Prohibitin, Flo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5319dd901d22a8bb11d56e14d4cf8598
https://pubmed.ncbi.nlm.nih.gov/34975153
https://pubmed.ncbi.nlm.nih.gov/34975153
Publikováno v:
Cancer Communications, Vol 42, Iss 1, Pp 56-59 (2022)
Cancer Communications
Cancer Communications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79377031dae78ab0bb33c6d8a6c7417
https://doi.org/10.1002/cac2.12248
https://doi.org/10.1002/cac2.12248
Autor:
Daxin Pang, Jinying Zhang, Mingzhou Li, Qianqian Zhu, Tianzhi Chen, Jingjing Huang, Chongyang Li, Ran Zhang, Minglei Zhi, Wei Xie, Dengfeng Gao, Hong-Jiang Wei, Yixuan Yao, Jianhui Tian, Qi Zhou, Shuai Gao, Qianzi Tang, Zicong Xie, Tang Hai, Deling Jiao, Keren Long, Xianya Huang, Caihong Zheng, Bofeng Liu, Dawei Yu, Yingjie Wang, Naixin Chen, Pengliang Liu, Xingxu Huang, Yu Lin, Jianxiong Guo, Xinze Chen, Jiaman Zhang, Mengxin Liu, Jie Gao, Guanglei Li, Suying Cao, Xiaogang Weng, Yan Liu, Qiuyan Li, Hongsheng Ouyang, Jingcang Yang, Jianyong Han, Yiliang Miao, Mengnan He, Zhonghua Liu, Zimo Zhao
Publikováno v:
Cell Res
Pig epiblast-derived pluripotent stem cells are considered to have great potential and broad prospects for human therapeutic model development and livestock breeding. Despite ongoing attempts since the 1990s, no stably defined pig epiblast-derived st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038b2d8a6a2e8e85b197e001711a847e
https://doi.org/10.1038/s41422-021-00592-9
https://doi.org/10.1038/s41422-021-00592-9