15-Hydroxyprostaglandin dehydrogenase is an in vivo suppressor of colon tumorigenesis

Autor: Lawrence, E., Newman, R. A., Dawson, D., Platzer, P., Guda, K., Luo, G., Lovgren, A. K., Myung, S.-J., Dannenberg, A. J., Willis, J., Rerko, R. M., Markowitz, S. D., Yan, M., Pretlow, T. P., Dotson, A.

15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is a prostaglandin-degrading enzyme that is highly expressed in normal colon mucosa but is ubiquitously lost in human colon cancers. Herein, we demonstrate that 15-PGDH is active in vivo as a highly pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe3ffebab0972588c7ad4e4d9003e1c2

Recombinant interleukin 12 cures mice infected with Leishmania major.

Autor: Heinzel, F P, Schoenhaut, D S, Rerko, R M, Rosser, L E, Gately, M K

Publikováno v: The Journal of Experimental Medicine; May 1993, Vol. 177 Issue: 5 p1505-1509, 5p

Cure of progressive murine leishmaniasis: interleukin 4 dominance is abolished by transient CD4(+) T cell depletion and T helper cell type 1-selective cytokine therapy.

Autor: Heinzel FP; Division of Geographic Medicine, Case Western Reserve University School of Medicine and the Research Service, Veteran's Affairs Medical Center, Cleveland, Ohio 44106-4983, USA. fxh10@po.cwru.edu, Rerko RM

Publikováno v: The Journal of experimental medicine [J Exp Med] 1999 Jun 21; Vol. 189 (12), pp. 1895-906.

In vivo production and function of IL-12 p40 homodimers.

Autor: Heinzel FP; Division of Geographic Medicine, Case Western Reserve University School of Medicine, and Veterans Affairs Medical Center, Cleveland, OH 44106, USA., Hujer AM, Ahmed FN, Rerko RM

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 1997 May 01; Vol. 158 (9), pp. 4381-8.

Immunoregulation of murine leishmaniasis by interleukin-12.

Autor: Heinzel FP; Division of Geographic Medicine, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Ahmed F, Hujer AM, Rerko RM

Publikováno v: Research in immunology [Res Immunol] 1995 Sep-Oct; Vol. 146 (7-8), pp. 575-81.