Zobrazeno 1 - 10
of 575
pro vyhledávání: '"Repurposed drugs"'
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 8, Pp 2059-2075 (2024)
Abstract Epidermolysis bullosa (EB) comprises rare genetic disorders characterized by skin and mucosal membrane blistering induced by mechanical trauma. Molecularly, pathogenic variants affect genes encoding proteins crucial for epidermal–dermal ad
Externí odkaz:
https://doaj.org/article/21d1918ad9fd49e2aa7b8dec0acb0d54
Autor:
Kusuma Sai Davuluri, Rajnandini Ghanghav, Gunwant Ahire, Mahadeo Kakade, Sarah Cherian, Kalichamy Alagarasu, Deepti Parashar
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Chikungunya virus (CHIKV) infection causes chikungunya, a viral disease that currently has no specific antiviral treatment. Several repurposed drug candidates have been investigated for the treatment of the disease. In order to improve the e
Externí odkaz:
https://doaj.org/article/7b3ce3dbdac240f2a2a9fcbd15c05534
Autor:
Popović Jovan K., Popović Dušica J., Popović Kosta J., Miljković Dejan, Lalošević Dušan, Dolićanin Zana, Čapo Ivan
Publikováno v:
Journal of the Serbian Chemical Society, Vol 89, Iss 5, Pp 643-656 (2024)
The aim was to detect and correlate anticancer effects of metformin in combinations with other repurposed drugs, already registered for other indications, which may be immediately applied and clinically investigated in oncology, reducing the time and
Externí odkaz:
https://doaj.org/article/54c2d2829fcf4e33bb3f5234ee15e197
Autor:
David Sánchez-Marín, Macrina Beatriz Silva-Cázares, Manuel González-Del Carmen, Alma D. Campos-Parra
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The diagnosis of thyroid cancer (TC) has increased dramatically in recent years. Papillary TC is the most frequent type and has shown a good prognosis. Conventional treatments for TC are surgery, hormonal therapy, radioactive iodine, chemotherapy, an
Externí odkaz:
https://doaj.org/article/be5a42e505a44fd28acebab5c848b8c7
Autor:
Lilibeth Arias, Kennedy Otwombe, Ziyaad Waja, Nestani Tukvadze, Tamta Korinteli, Tumelo Moloantoa, Kaori L Fonseca, Natasha Pillay, Thabiso Seiphetlo, Dan Ouchi-Vernet, Adrian Siles, Lidia Carabias, Carles Quiñones, Sergo Vashakidze, Neil Martinson, Cristina Vilaplana
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background The duration and regimen of tuberculosis (TB) treatment is currently based predominantly on whether the M. tuberculosis (Mtb) strain is drug-sensitive (DS) or multidrug-resistant (MDR) with doses adjusted by patients’ weight onl
Externí odkaz:
https://doaj.org/article/84f87ca4e04d4ec18d56201863085e5a
Autor:
Nattinee Lochaiyakun, Potjanee Srimanote, Onruedee Khantisitthiporn, Jeeraphong Thanongsaksrikul
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 785 (2024)
The open-source drug library, namely, MMV Pandemic Response Box, contains 153 antiviral agents, a chemically and pharmacologically diverse mixture of early-stage, emerging anti-infective scaffolds, and mature compounds currently undergoing clinical d
Externí odkaz:
https://doaj.org/article/bb756f47bf1b4f9495ff86f4b1daecfa
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
The COVID-19 pandemic was declared due to the spread of the novel coronavirus, SARS-CoV-2. Viral infection is caused by the interaction between the SARS-CoV-2 receptor binding domain (RBD) and the human ACE2 receptor (hACE2). Previous computational s
Externí odkaz:
https://doaj.org/article/7df89489dd91466b8fdbd9d69c2ec482
Autor:
Suraj Kapoor
Publikováno v:
Journal of Public Health and Primary Care, Vol 4, Iss 1, Pp 4-7 (2023)
Traditional drug development and discovery have not kept speed with warnings from emerging and re-emerging diseases such as Zika, Nipah, Ebola virus, MERS-CoV, and more newly the pandemic of COVID-19. The new drug discovery has a limitation of high a
Externí odkaz:
https://doaj.org/article/c2f4f1af94da4a0eaf20e4f11267fb77
Autor:
Denis Voronin, Nancy Tricoche, Ricardo Peguero, Anna Maria Kaminska, Elodie Ghedin, Judy A. Sakanari, Sara Lustigman
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 256 (2024)
Onchocerciasis and lymphatic filariasis are two neglected tropical diseases caused by filarial nematodes that utilize insect vectors for transmission to their human hosts. Current control strategies are based on annual or biannual mass drug administr
Externí odkaz:
https://doaj.org/article/53a95d5f5f1c4fd998ed4b21b7bca319
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.