The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism

Autor: Ganesan Senthil Kumar, Ezgi Gokhan, Sofie De Munter, Mathieu Bollen, Paola Vagnarelli, Wolfgang Peti, Rebecca Page

Publikováno v: eLife, Vol 5 (2016)

Ki-67 and RepoMan have key roles during mitotic exit. Previously, we showed that Ki-67 organizes the mitotic chromosome periphery and recruits protein phosphatase 1 (PP1) to chromatin at anaphase onset, in a similar manner as RepoMan (Booth et al., 2

Externí odkaz: https://doaj.org/article/70a7b979206b4203b719b7759ca631c2

A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions

Autor: Dan Wu, Veerle De Wever, Rita Derua, Aleyde Van Eynde, Mathieu Bollen, Monique Beullens, Claudia Winkler

Publikováno v: The Journal of biological chemistry. 293(39)

The protein Ser/Thr phosphatase PP1 catalyzes an important fraction of protein dephosphorylation events and forms highly specific holoenzymes through an association with regulatory interactors of protein phosphatase one (RIPPOs). The functional chara

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6f66d130603e34581cde9988169139
https://pubmed.ncbi.nlm.nih.gov/30115685

The Ki-67 and Repoman mitotic phosphatases assemble via an identical, yet novel mechanism

Autor: Sofie De Munter, Mathieu Bollen, Ezgi Gokhan, Ganesan Senthil Kumar, Rebecca Page, Paola Vagnarelli, Wolfgang Peti

Publikováno v: eLife, Vol 5 (2016)
eLife

Ki-67 and RepoMan have key roles during mitotic exit. Previously, we showed that Ki-67 organizes the mitotic chromosome periphery and recruits protein phosphatase 1 (PP1) to chromatin at anaphase onset, in a similar manner as RepoMan (Booth et al., 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1734ee014d2ff8ba47bde54d4888d282
http://bura.brunel.ac.uk/handle/2438/13086

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The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism.

Autor: Kumar GS; Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, United States., Gokhan E; College of Health and Life Science, Research Institute for Environment, Health and Society, Brunel University London, Uxbridge, United Kingdom., De Munter S; Laboratory of Biosignaling and Therapeutics, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Bollen M; Laboratory of Biosignaling and Therapeutics, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Vagnarelli P; College of Health and Life Science, Research Institute for Environment, Health and Society, Brunel University London, Uxbridge, United Kingdom., Peti W; Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, United States., Page R; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, United States.

Publikováno v: ELife [Elife] 2016 Aug 30; Vol. 5. Date of Electronic Publication: 2016 Aug 30.