Zobrazeno 1 - 10
of 263
pro vyhledávání: '"Replicative capacity"'
Autor:
Ling Yue, Rui Xu, Samantha Mclnally, Qianhong Qin, Jake W. Rhodes, Erick Muok, Gisele Umviligihozo, Kelsie Brooks, Jiayi Zhang, Zhaohui Qin, Jean Bizimana, Jonathan Hare, Matthew A. Price, Susan A. Allen, Etienne Karita, Eric Hunter
Publikováno v:
Viruses, Vol 16, Iss 11, p 1706 (2024)
HIV-1 subtypes have distinct geographical distributions, with subtypes A, C, and D and inter-subtype recombinants circulating in sub-Saharan Africa. Historically, individuals living with subtype A viruses exhibit slower CD4 decline and progression to
Externí odkaz:
https://doaj.org/article/e08124aee663449db461dbfda7e63337
Akademický článek
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Autor:
Claiborne, Daniel T., Prince, Jessica L., Scully, Eileen, Macharia, Gladys, Micci, Luca, Lawson, Benton, Kopycinski, Jakub, Deymier, Martin J., Vanderford, Thomas H., Nganou-Makamdop, Krystelle, Ende, Zachary, Brooks, Kelsie, Tang, Jianming, Yu, Tianwei, Lakhi, Shabir, Kilembe, William, Silvestri, Guido, Douek, Daniel, Goepfert, Paul A., Price, Matthew A., Allen, Susan A., Paiardini, Mirko, Altfeld, Marcus, Gilmour, Jill, Hunter, Eric
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Mar . 112(12), E1480-E1489.
Externí odkaz:
https://www.jstor.org/stable/26462178
Autor:
Miyako Okane, Steffen Wildum, Keiko Baba, Shinya Omoto, Akira Naito, Takao Shishido, Kae Inoue, Satoshi Hata, Takashi Hashimoto
Publikováno v:
Influenza and Other Respiratory Viruses
Background Baloxavir marboxil (BXM) is an approved drug that selectively targets cap‐dependent endonuclease on PA subunit in the RNA polymerase complex of influenza A and B viruses. Amino acid substitutions at position 38 in the PA subunit were ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6258c0569b1328f9a007782e0760ae
https://doi.org/10.1111/irv.12821
https://doi.org/10.1111/irv.12821
Publikováno v:
Biotechnic & Histochemistry. 95:490-498
We investigated the effect of prolonged rhBMP-2 treatment on telomerase activity, replicative capacity and senescence of nucleus pulposus cells (NPCs) during long term culture. We obtained intervertebral disc (IVD) tissues with grade III degeneration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f262638c4d52d40e272ac2f59f80c0c
https://doi.org/10.1080/10520295.2020.1721560
https://doi.org/10.1080/10520295.2020.1721560
Publikováno v:
Frontiers in Immunology, Vol 6 (2016)
Killing of HIV-infected cells by CD8+ T-cells imposes strong selection pressure on the virus towards escape. The HLA class I molecules that are successful in mediating some degree of control over the virus are those that tend to present epitopes in c
Externí odkaz:
https://doaj.org/article/f51f9225ca934f18a62ffbaebc8cf55f
Publikováno v:
Biomedical Papers, Vol 163, Iss 1, Pp 1-7 (2019)
Telomeres are repetitive DNA sequences protecting physical ends of linear chromosomes against degradation and end-to-end chromosomal fusion. Telomeres shorten with each cell division, which regulates the cellular lifespan in somatic cells and limits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e304d0b6feb37c6bfc81e534fc6d9b4c
https://doi.org/10.5507/bp.2018.084
https://doi.org/10.5507/bp.2018.084
Autor:
Dan Otelea, Robert Hohan, Ovidiu Vlaicu, Dragoş Florea, Corina Casangiu, Petre Milu, Oana Săndulescu, Marius Surleac, Anca Streinu-Cercel, Andreea Tudor, Simona Paraschiv, Leontina Banica
Publikováno v:
AIDS Research and Human Retroviruses
New SARS-CoV-2 variants are constantly emerging and putting a strain on public health systems by spreading faster and potentially evading immune protection through vaccination. One of these strains is the B.1.1.7 variant that has initially been descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6d3a846d42fbee37d32f99b2a2eefe
https://pubmed.ncbi.nlm.nih.gov/33544010
https://pubmed.ncbi.nlm.nih.gov/33544010
Publikováno v:
Antioxidants & Redox Signaling
Significance: Cell senescence was originally defined by an acute loss of replicative capacity and thus believed to be restricted to proliferation-competent cells. More recently, senescence has been recognized as a cellular stress and damage response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f90a51104a0e588f55ec8d0ecb0fe98
https://pubmed.ncbi.nlm.nih.gov/32164429
https://pubmed.ncbi.nlm.nih.gov/32164429
Autor:
William K. Reisen, Michèle Frey, Nisha K. Duggal, Aaron C. Brault, Andra A. Hutton, Gabriella Worwa
Publikováno v:
Virology. 514:170-181
To investigate the phenotypic evolution of West Nile virus (WNV) in California, we competed sixteen isolates made during 2007–08 against COAV997-5nt, a genetically marked clone from the founding 2003 California isolate COAV997-2003. Using in vivo f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e26aa03605f9d6c70c210317b184a41
https://doi.org/10.1016/j.virol.2017.11.017
https://doi.org/10.1016/j.virol.2017.11.017