Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Replication compartment"'
Publikováno v:
Viruses, Vol 16, Iss 6, p 845 (2024)
Viruses exploit the host cell machinery to enable infection and propagation. This review discusses the complex landscape of DNA virus–host interactions, focusing primarily on herpesviruses and adenoviruses, which replicate in the nucleus of infecte
Externí odkaz:
https://doaj.org/article/d9708d2488724d13b7605eebc2b61af6
Autor:
Kyle R. Smith, Somnath Paul, Qiwen Dong, Orchi Anannya, Darby G. Oldenburg, J. Craig Forrest, Kevin M. McBride, Laurie T. Krug
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT Herpesviruses are large double-stranded DNA viruses that encode core replication proteins and accessory factors involved in nucleotide metabolism and DNA repair. Mammalian uracil-DNA glycosylases (UNG) excise deleterious uracil residues from
Externí odkaz:
https://doaj.org/article/db2ec48fefc6463ba061614bbbfb2d73
Autor:
Hana Mahmutefendić Lučin, Silvija Lukanović Jurić, Marina Marcelić, Igor Štimac, Ivona Viduka, Gordana Blagojević Zagorac, Berislav Lisnić, Zsolt Ruzsics, Pero Lučin
Publikováno v:
Viruses, Vol 15, Iss 3, p 766 (2023)
Extensive reorganization of infected cells and the formation of large structures known as the nuclear replication compartment (RC) and cytoplasmic assembly compartment (AC) is a hallmark of beta-herpesvirus infection. These restructurings rely on ext
Externí odkaz:
https://doaj.org/article/6c91193966ea4c8e885948e4e961a4af
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110411- (2022)
Summary: Epstein-Barr virus (EBV) persistently infects people worldwide. Delivery of ∼170-kb EBV genomes to nuclei and use of nuclear membrane-less replication compartments (RCs) for their lytic cycle amplification necessitate evasion of intrinsic
Externí odkaz:
https://doaj.org/article/ef47e811be844bf3aa84bf5e5a6b5bb0
Autor:
Enrico Caragliano, Stefano Bonazza, Giada Frascaroli, Jiajia Tang, Timothy K. Soh, Kay Grünewald, Jens B. Bosse, Wolfram Brune
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110469- (2022)
Summary: Human cytomegalovirus (HCMV) replicates its DNA genome in specialized replication compartments (RCs) in the host cell nucleus. These membrane-less organelles originate as spherical structures and grow in size over time. However, the mechanis
Externí odkaz:
https://doaj.org/article/19f814b0feb24c2395020321e8b28f80
Akademický článek
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Publikováno v:
Viruses, Vol 14, Iss 5, p 960 (2022)
Recent progress has provided clear evidence that many RNA-viruses form cytoplasmic biomolecular condensates mediated by liquid–liquid phase separation to facilitate their replication. In contrast, seemingly contradictory data exist for herpesviruse
Externí odkaz:
https://doaj.org/article/9fe722d3707f499a8f4f684e68cb9441
Autor:
Atsuko Sugimoto
Publikováno v:
Microorganisms, Vol 10, Iss 5, p 896 (2022)
During Epstein–Barr virus (EBV) lytic replication, viral DNA synthesis is carried out in viral replication factories called replication compartments (RCs), which are located at discrete sites in the nucleus. Viral proteins constituting the viral re
Externí odkaz:
https://doaj.org/article/5bf8c1f929194c1dbcf7c8002b0f9917
Akademický článek
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Autor:
Matthew Charman, Matthew D. Weitzman
Publikováno v:
Viruses, Vol 12, Iss 2, p 151 (2020)
DNA viruses that replicate in the nucleus encompass a range of ubiquitous and clinically important viruses, from acute pathogens to persistent tumor viruses. These viruses must co-opt nuclear processes for the benefit of the virus, whilst evading hos
Externí odkaz:
https://doaj.org/article/c650ed84ca62427798b01c3c2e69f3ab