Evaluation of the stability of furosemide in tablet form during six-month storage in spaceflight and peculiarities of its pharmacokinetics and pharmacodynamics under conditions of anti-orthostatic hypokinesia.

Autor: Polyakov AV; Development of Means and Methods of Medical Care in Extreme Conditions and Telemedicine of the State Scientific Centre of the Russian Federation - Institute of Medical and Biological Problems of the Russian Academy of Sciences, Moscow, Russian Federation., Svistunov AA; Department of Clinical Pharmacology and Propaedeutics of Internal Diseases, Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russian Federation., Kondratenko SN; Department of Clinical Pharmacology and Propaedeutics of Internal Diseases, Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russian Federation., Kovachevich IV; Development of Means and Methods of Medical Care in Extreme Conditions and Telemedicine of the State Scientific Centre of the Russian Federation - Institute of Medical and Biological Problems of the Russian Academy of Sciences, Moscow, Russian Federation., Repenkovа LG; Development of Means and Methods of Medical Care in Extreme Conditions and Telemedicine of the State Scientific Centre of the Russian Federation - Institute of Medical and Biological Problems of the Russian Academy of Sciences, Moscow, Russian Federation., Savelyevа MI; Department of Clinical Pharmacology and Therapy, Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia, Moscow, Russian Federation., Shikh EV; Department of Clinical Pharmacology and Propaedeutics of Internal Diseases, Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russian Federation., Noskov VB; Development of Means and Methods of Medical Care in Extreme Conditions and Telemedicine of the State Scientific Centre of the Russian Federation - Institute of Medical and Biological Problems of the Russian Academy of Sciences, Moscow, Russian Federation.

Publikováno v: Drug metabolism and personalized therapy [Drug Metab Pers Ther] 2022 Feb 24; Vol. 37 (3), pp. 249-259. Date of Electronic Publication: 2022 Feb 24 (Print Publication: 2022).