Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Rep-Seq"'
Autor:
Qilong Wang, Huikun Zeng, Yan Zhu, Minhui Wang, Yanfang Zhang, Xiujia Yang, Haipei Tang, Hongliang Li, Yuan Chen, Cuiyu Ma, Chunhong Lan, Bin Liu, Wei Yang, Xueqing Yu, Zhenhai Zhang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Antibody repertoire sequencing (Rep-seq) has been widely used to reveal repertoire dynamics and to interrogate antibodies of interest at single nucleotide-level resolution. However, polymerase chain reaction (PCR) amplification introduces extensive a
Externí odkaz:
https://doaj.org/article/e714c179e41249f9ac2871baef2ce53f
Publikováno v:
MicrobiologyOpen, Vol 10, Iss 6, Pp n/a-n/a (2021)
Abstract Identification, source tracking, and surveillance of food pathogens are crucial factors for the food‐producing industry. Over the last decade, the techniques used for this have moved from conventional enrichment methods, through species‐
Externí odkaz:
https://doaj.org/article/be8fb991d0204333b000f59f54dbf427
Autor:
Yanfang Zhang, Tianjian Chen, Huikun Zeng, Xiujia Yang, Qingxian Xu, Yanxia Zhang, Yuan Chen, Minhui Wang, Yan Zhu, Chunhong Lan, Qilong Wang, Haipei Tang, Yan Zhang, Chengrui Wang, Wenxi Xie, Cuiyu Ma, Junjie Guan, Shixin Guo, Sen Chen, Wei Yang, Lai Wei, Jian Ren, Xueqing Yu, Zhenhai Zhang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The antibody repertoire is a critical component of the adaptive immune system and is believed to reflect an individual’s immune history and current immune status. Delineating the antibody repertoire has advanced our understanding of humoral immunit
Externí odkaz:
https://doaj.org/article/2dd953d35bac4f9d98db37979ca17da9
Autor:
Scott Christley, Ademar Aguiar, George Blanck, Felix Breden, Syed Ahmad Chan Bukhari, Christian E. Busse, Jerome Jaglale, Srilakshmy L. Harikrishnan, Uri Laserson, Bjoern Peters, Artur Rocha, Chaim A. Schramm, Sarah Taylor, Jason Anthony Vander Heiden, Bojan Zimonja, Corey T. Watson, Brian Corrie, Lindsay G. Cowell
Publikováno v:
Frontiers in Big Data, Vol 3 (2020)
The Adaptive Immune Receptor Repertoire (AIRR) Community is a research-driven group that is establishing a clear set of community-accepted data and metadata standards; standards-based reference implementation tools; and policies and practices for inf
Externí odkaz:
https://doaj.org/article/11a666e9b5fc4c998941829a06ba9514
Autor:
Scott Christley, Mikhail K. Levin, Inimary T. Toby, John M. Fonner, Nancy L. Monson, William H. Rounds, Florian Rubelt, Walter Scarborough, Richard H. Scheuermann, Lindsay G. Cowell
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-5 (2017)
Abstract Background Pre-processing of high-throughput sequencing data for immune repertoire profiling is essential to insure high quality input for downstream analysis. VDJPipe is a flexible, high-performance tool that can perform multiple pre-proces
Externí odkaz:
https://doaj.org/article/26c993d5cb694e45b75adc076995ae4a
sumrep: A Summary Statistic Framework for Immune Receptor Repertoire Comparison and Model Validation
Autor:
Branden J. Olson, Pejvak Moghimi, Chaim A. Schramm, Anna Obraztsova, Duncan Ralph, Jason A. Vander Heiden, Mikhail Shugay, Adrian J. Shepherd, William Lees, Frederick A. Matsen
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The adaptive immune system generates an incredible diversity of antigen receptors for B and T cells to keep dangerous pathogens at bay. The DNA sequences coding for these receptors arise by a complex recombination process followed by a series of prod
Externí odkaz:
https://doaj.org/article/22073bd60c67415fa63b32924d8b4d9e
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2016 Jul 01. 113(28), 7846-7851.
Externí odkaz:
https://www.jstor.org/stable/26470806
Autor:
Syed Ahmad Chan Bukhari, Martin J. O’Connor, Marcos Martínez-Romero, Attila L. Egyedi, Debra Willrett, John Graybeal, Mark A. Musen, Florian Rubelt, Kei-Hoi Cheung, Steven H. Kleinstein
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The adaptation of high-throughput sequencing to the B cell receptor and T cell receptor has made it possible to characterize the adaptive immune receptor repertoire (AIRR) at unprecedented depth. These AIRR sequencing (AIRR-seq) studies offer tremend
Externí odkaz:
https://doaj.org/article/e28f95a5137843d3a78e695d29ec81b2
Autor:
Evgeny S. Egorov, Sofya A. Kasatskaya, Vasiliy N. Zubov, Mark Izraelson, Tatiana O. Nakonechnaya, Dmitriy B. Staroverov, Andrea Angius, Francesco Cucca, Ilgar Z. Mamedov, Elisa Rosati, Andre Franke, Mikhail Shugay, Mikhail V. Pogorelyy, Dmitriy M. Chudakov, Olga V. Britanova
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Human aging is associated with a profound loss of thymus productivity, yet naïve T lymphocytes still maintain their numbers by division in the periphery for many years. The extent of such proliferation may depend on the cytokine environment, includi
Externí odkaz:
https://doaj.org/article/3353536f827240dd8de351aabf48629c
Autor:
Scott Christley, Walter Scarborough, Eddie Salinas, William H. Rounds, Inimary T. Toby, John M. Fonner, Mikhail K. Levin, Min Kim, Stephen A. Mock, Christopher Jordan, Jared Ostmeyer, Adam Buntzman, Florian Rubelt, Marco L. Davila, Nancy L. Monson, Richard H. Scheuermann, Lindsay G. Cowell
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
BackgroundRecent technological advances in immune repertoire sequencing have created tremendous potential for advancing our understanding of adaptive immune response dynamics in various states of health and disease. Immune repertoire sequencing produ
Externí odkaz:
https://doaj.org/article/ccf807b5dbf248eeac1ed7188f9e63bd