Výsledky vyhledávání - "Reo Fukushima"

Akademický článek

Generation of bone-specific lysyl hydroxylase 2 knockout mice and their phenotypes

Autor: Kenta Tsuneizumi, Atsushi Kasamatsu, Tomoaki Saito, Reo Fukushima, Yuki Taga, Kazunori Mizuno, Masataka Sunohara, Katsuhiro Uzawa, Mitsuo Yamauchi

Publikováno v: Biochemistry and Biophysics Reports, Vol 39, Iss , Pp 101790- (2024)

Lysyl hydroxylase 2 (LH2) catalyzes the hydroxylation of lysine residues in the telopeptides of type I collagen. This modification is critical for the formation of stable hydroxylysine-aldehyde derived collagen cross-links, thus, for the stability of

Externí odkaz: https://doaj.org/article/f00a881d2d0f4b26b3db9551a84cf625

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Akademický článek

A novel cell-based transplantation method using a Rho kinase inhibitor and a specific catheter device for the treatment of salivary gland damage after head and neck radiotherapy

Autor: Atsushi Kasamatsu, Reo Fukushima, Koki Nakamura, Kohei Kawasaki, Shusaku Yoshimura, Tomoyoshi Koyama, Chonji Fukumoto, Isao Miyamoto, Katsuhiro Uzawa

Publikováno v: Biochemistry and Biophysics Reports, Vol 32, Iss , Pp 101385- (2022)

Radiotherapy (RT) for head and neck cancer results in irreversible damage to salivary glands (SGs) and decreases saliva production, leading to a dry mouth. To date, there are no satisfactory therapies to solve this problem. We recently established a

Externí odkaz: https://doaj.org/article/7aee4dd039dc4b9aa542493a601f5446

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Tumor Suppressive Circular RNA-102450: Development of a Novel Diagnostic Procedure for Lymph Node Metastasis from Oral Cancer

Autor: Manabu Iyoda, Yosuke Endo-Sakamoto, Kohei Kawasaki, Dai Nakashima, Reo Fukushima, Kazuya Hiroshima, Toshiaki Ando, Atsushi Kasamatsu, Katsuhiro Uzawa

Publikováno v: Cancers, Vol 13, Iss 5708, p 5708 (2021)
Cancers
Volume 13
Issue 22

Simple Summary Circular RNAs (circRNAs) consist of covalently closed structures without a free 3′ poly(A) tail or 5′ cap. Due to their loop structures, circRNAs are largely stable and resistant to RNA degradation by endonucleases. Therefore, they

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a844b064447e3519f1f4a894b17e6425
https://www.mdpi.com/2072-6694/13/22/5708

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Contrasting functions of the epithelial‑stromal interaction 1 gene, in human oral and lung squamous cell cancers

Autor: Makoto Arai, Yuichi Takiguchi, Hideki Tanzawa, Naoya Kato, Tetsuhiro Chiba, Masashi Shiiba, Reo Fukushima, Katsuhiro Uzawa, Akinobu Tawada, Mengmeng Fan

Publikováno v: Oncology Reports

The epithelial‑stromal interaction 1 gene (EPSTI1) is known to play multiple roles in the malignant progression of breast cancer and also in some aspects of the immune responses to the tumor. However, the relevance of the gene in the onset/progress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827cdd9e3fc82b8840758ffa4f6d5bad
https://pubmed.ncbi.nlm.nih.gov/34738627

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Overexpression of Translocation Associated Membrane Protein 2 Leading to Cancer-Associated Matrix Metalloproteinase Activation as a Putative Metastatic Factor for Human Oral Cancer

Autor: Katsuhiro Uzawa, Kazuaki Fushimi, Hideki Tanzawa, Morihiro Higo, Yosuke Endo-Sakamoto, Hiroki Kasama, Dai Nakashima, Masashi Shiiba, Atsushi Kasamatsu, Reo Fukushima

Publikováno v: Journal of Cancer. 9:3326-3333

Translocation associated membrane protein 2 (TRAM2) has been characterized as a component of the translocon that is a gated channel at the endoplasmic reticulum (ER) membrane. TRAM2 is expressed in a wide variety of human organs. To date, no informat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54484a02d6acdba57021c2565f6172e
https://doi.org/10.7150/jca.25666

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Tspan15 plays a crucial role in metastasis in oral squamous cell carcinoma

Autor: Masashi Shiiba, Reo Fukushima, Manabu Iyoda, Dai Nakashima, Kazuya Hiroshima, Kazuyuki Koike, Sho Ishida, Hideki Tanzawa, Katsuhiro Uzawa, Fumihiko Hayashi, Noritoshi Oka

Publikováno v: Experimental cell research. 384(2)

Tetraspanin 15 (Tspan15) is a member of the tetraspanin family, which is associated with various biological events and several diseases, however, its role in human oral squamous cell carcinoma (OSCC) remains unknown. The current study aimed to clarif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27152bb7f1b11bb1df659b8303b91dec
https://pubmed.ncbi.nlm.nih.gov/31518558

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Abstract 2580: Contrasting functions of EPSTI1 in human oral and lung squamous cell cancer cell lines - its tumor promoting roles in oral and tumor suppressing roles in lung squamous cell carcinomas

Autor: Meng Meng Fan, Katsuhiro Uzawa, Tetsuhiro Chiba, Makoto Arai, Hideki Tanzawa, Naoya Kato, Reo Fukushima, Yuichi Takiguchi, Masashi Shiiba, Akinobu Tawada

Publikováno v: Cancer Research. 80:2580-2580

Introduction: Epithelial-stromal interaction 1 (EPSTI1) is a gene mapped to human chromosome 13q13.3. Recent studies have shown that EPSTI1 regulates many malignant features of cancers. However, the relevance of EPSTI1 to oral squamous cell carcinoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b5d5c581b7a3415e0f14a36fbb52308
https://doi.org/10.1158/1538-7445.am2020-2580

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